Featured Research

from universities, journals, and other organizations

Genetic mutation linked to asbestos exposure, mouse study suggests

Date:
June 20, 2011
Source:
University of Haifa
Summary:
Mice inhabiting an area known for its high concentration of asbestos-contaminated dust, have a higher level of genetic somatic mutations, compared with other regions where asbestos pollution levels are lower.

Mice inhabiting a northern town of Israel known for its high concentration of asbestos-contaminated dust, have a higher level of genetic somatic mutations, compared with other regions where asbestos pollution levels are lower. This has been shown in a new study carried out by Dr. Rachel Ben-Shlomo and Dr. Uri Shanas of the University of Haifa's Department of Biology in Oranim. "This study clearly indicates that there is a link between the higher levels of asbestos in the environment and the frequency of genetic somatic mutations in the mammals," the scientists said.

Earlier studies of asbestos have already shown that the thin fibers, which penetrate the body by inhalation or through consumption of food contaminated with the material, not only cause certain cancers but also genetic mutations in DNA structures. It is also known that asbestos is a material that decomposes slowly, over many years. Data from the Israeli Ministry of Health indicate a rise in the number of cancer patients from exposure to asbestos in the Western Galilee region of northern Israel, and therefore the scientists set out to examine whether genetic mutations are found in the mouse population living in its northern town of Nahariya. They chose to probe mutations in mice because their generations are renewed every three months, so it could be assumed for the study that dozens of generations of this sample population in Nahariya had already been exposed to the fibers.

Wild mice from two locations were sampled -- one group living close to a factory that manufactured asbestos-based products in Nahariya during 1952-1997, and a second group from a town located 50 kilometers, or 31 miles, from Nahariya and where no known asbestos pollutants are found. Samples were taken from both groups and six sites in the DNA were examined for genetic differences between the groups.

The results indicated differences between the groups' DNA and that the Nahariya-based mice had higher levels of genetic somatic mutations.

"These findings teach us that the pollutive, mutagenic asbestos increases somatic mutational frequency, which can in turn heighten the chances of developing cancerous growths," the researchers concluded.


Story Source:

The above story is based on materials provided by University of Haifa. Note: Materials may be edited for content and length.


Journal Reference:

  1. Rachel Ben-Shlomo, Uri Shanas. Genetic ecotoxicology of asbestos pollution in the house mouse Mus musculus domesticus. Environmental Science and Pollution Research, 2011; DOI: 10.1007/s11356-011-0481-9

Cite This Page:

University of Haifa. "Genetic mutation linked to asbestos exposure, mouse study suggests." ScienceDaily. ScienceDaily, 20 June 2011. <www.sciencedaily.com/releases/2011/06/110615094518.htm>.
University of Haifa. (2011, June 20). Genetic mutation linked to asbestos exposure, mouse study suggests. ScienceDaily. Retrieved July 28, 2014 from www.sciencedaily.com/releases/2011/06/110615094518.htm
University of Haifa. "Genetic mutation linked to asbestos exposure, mouse study suggests." ScienceDaily. www.sciencedaily.com/releases/2011/06/110615094518.htm (accessed July 28, 2014).

Share This




More Health & Medicine News

Monday, July 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

$15B Deal on Vets' Health Care Reached

$15B Deal on Vets' Health Care Reached

AP (July 28, 2014) A bipartisan deal to improve veterans health care would authorize at least $15 billion in emergency spending to fix a veterans program scandalized by long patient wait times and falsified records. (July 28) Video provided by AP
Powered by NewsLook.com
Traditional African Dishes Teach Healthy Eating

Traditional African Dishes Teach Healthy Eating

AP (July 28, 2014) Classes are being offered nationwide to encourage African Americans to learn about cooking fresh foods based on traditional African cuisine. The program is trying to combat obesity, heart disease and other ailments often linked to diet. (July 28) Video provided by AP
Powered by NewsLook.com
West Africa Gripped by Deadly Ebola Outbreak

West Africa Gripped by Deadly Ebola Outbreak

AFP (July 28, 2014) The worst-ever outbreak of the deadly Ebola epidemic grips west Africa, killing hundreds. Duration: 00:48 Video provided by AFP
Powered by NewsLook.com
Trees Could Save More Than 850 Lives Each Year

Trees Could Save More Than 850 Lives Each Year

Newsy (July 27, 2014) A national study conducted by the USDA Forest Service found that trees collectively save more than 850 lives on an annual basis. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins