Featured Research

from universities, journals, and other organizations

CT scans unleash a breakthrough in catching early stage lung cancer

Date:
June 30, 2011
Source:
Northwestern Memorial Hospital
Summary:
The National Lung Screening Trial (NLST) is the first scientific study that provides clear evidence that CT screening significantly reduces the death rate due to lung cancer. NLST data shows 20 percent fewer lung cancer deaths among trial participants who had the CT scan compared with the chest X-ray. Until now, no screening test for lung cancer has proven effective in detecting tumors at an early, more treatable stage.

The National Lung Screening Trial (NLST) is the first scientific study that provides clear evidence that CT screening significantly reduces the death rate due to lung cancer. NLST data shows 20 percent fewer lung cancer deaths among trial participants who had the CT scan compared with the chest x-ray. Until now, no screening test for lung cancer has proven effective in detecting tumors at an early, more treatable stage.

Northwestern Memorial Hospital is the only NLST site in Chicago. During the study period, more than 400 individuals enrolled in the trial locally. "We are extremely grateful to the participants in both the chest X-ray and the CT scan arms who volunteered for this lengthy and challenging trial," said Eric M. Hart, MD, a radiologist and the NLST Site Principal Investigator at Northwestern Memorial Hospital. "Their continued involvement is the basis for this ray of hope for other heavy smokers."

The trial was conducted at 33 sites throughout the country and included more than 53,000 current or former "heavy smokers" between the ages of 55 and 74. Each participant was either a former heavy smoker within the last 15 years or a current smoker with at least a 30 pack year history of smoking (calculated by the number of packs per day times the number of years smoking). Between 2002 and 2004, the participants were randomly assigned to receive either a chest x-ray or a CT scan annually for three years. Then, they were monitored for the following five years.

Lung Cancer is one of the most common and lethal forms of cancer in the U.S. Lung cancer usually grows silently for years before symptoms arise that lead to diagnosis and treatment. By then, the cancer has typically reached an advanced stage where treatment is difficult and cure rates are low.

"We will continue to promote smoking cessation as the primary strategy for lung cancer prevention," Malcolm DeCamp, MD, chief of division of thoracic surgery at Northwestern Memorial, states. "But now, we have an effective screening technique that we must promote throughout the entire community to detect lung cancer in its earliest stage."

The NLST is sponsored by the National Cancer Institute (NCI) and conducted by the American College of Radiology Imaging Network (ACRIN) and the Lung Cancer Study Group.


Story Source:

The above story is based on materials provided by Northwestern Memorial Hospital. Note: Materials may be edited for content and length.


Journal Reference:

  1. The National Lung Screening Trial Research Team. Reduced Lung-Cancer Mortality with Low-Dose Computed Tomographic Screening. New England Journal of Medicine, 2011; DOI: 10.1056/NEJMoa1102873

Cite This Page:

Northwestern Memorial Hospital. "CT scans unleash a breakthrough in catching early stage lung cancer." ScienceDaily. ScienceDaily, 30 June 2011. <www.sciencedaily.com/releases/2011/06/110630091823.htm>.
Northwestern Memorial Hospital. (2011, June 30). CT scans unleash a breakthrough in catching early stage lung cancer. ScienceDaily. Retrieved September 30, 2014 from www.sciencedaily.com/releases/2011/06/110630091823.htm
Northwestern Memorial Hospital. "CT scans unleash a breakthrough in catching early stage lung cancer." ScienceDaily. www.sciencedaily.com/releases/2011/06/110630091823.htm (accessed September 30, 2014).

Share This



More Health & Medicine News

Tuesday, September 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

How 'Yes Means Yes' Defines Sexual Assault

How 'Yes Means Yes' Defines Sexual Assault

Newsy (Sep. 29, 2014) Aimed at reducing sexual assaults on college campuses, California has adopted a new law changing the standard of consent for sexual activity. Video provided by Newsy
Powered by NewsLook.com
Scientists May Have Found An Early Sign Of Pancreatic Cancer

Scientists May Have Found An Early Sign Of Pancreatic Cancer

Newsy (Sep. 29, 2014) Researchers looked at 1,500 blood samples and determined people who developed pancreatic cancer had more branched chain amino acids. Video provided by Newsy
Powered by NewsLook.com
Colo. Doctors See Cluster of Enterovirus Cases

Colo. Doctors See Cluster of Enterovirus Cases

AP (Sep. 29, 2014) Doctors at the Children's Hospital of Colorado say they have treated over 4,000 children with serious respiratory illnesses since August. Nine of the patients have shown distinct neurological symptoms, including limb weakness. (Sept. 29) Video provided by AP
Powered by NewsLook.com
Dr.'s Unsure of Cause of Fast-Spreading Virus

Dr.'s Unsure of Cause of Fast-Spreading Virus

AP (Sep. 29, 2014) Doctors at the Children's Hospital of Colorado say they have treated over 4,000 children with serious respiratory illnesses since August. Nine of the patients have shown distinct neurological symptoms, including limb weakness. (Sept. 29) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins