Featured Research

from universities, journals, and other organizations

For the first time, the European IVF Monitoring Group reports on cycles using frozen eggs

Date:
July 6, 2011
Source:
European Society of Human Reproduction and Embryology
Summary:
With 3,284 cycles using frozen eggs, Italy is the leader in Europe, researchers say. Other important data the European IVF Monitoring group (EIM) on 2008 cycles and the International Committee Monitoring Assisted Reproductive Technologies (ICMART) on 2007 cycles highlighted were Sweden's low rate of multiple births -- the lowest in the world -- and Spain's 30 % share of egg donations in Europe.

With 3,284 cycles using frozen eggs, Italy is the leader in Europe, the 27th Annual Meeting of the European Society of Human Reproduction and Embryology heard July 6 2011. Other important data the European IVF Monitoring group (EIM) on 2008 cycles and the International Committee Monitoring Assisted Reproductive Technologies (ICMART) on 2007 cycles highlighted were Sweden's low rate of multiple births -- the lowest in the world -- and Spain's 30 % share of egg donations in Europe.

The EIM collected data on frozen oocyte retrieval (FOR) cycles for the first time. Until today, egg freezing is still not offered on a wide scale but can be an option for women who wish to postpone motherhood or are facing cancer therapy to save their lives. Recently, vitrification techniques have offered oocyte survival rates in excess of 90 % and implantation rates per transfer that are comparable with fresh eggs. Scientists still face problems such as poor oocyte survival post-thaw, low fertilisation rates, cytoskeletal damage during vitrification and poor reproducibility of results.

"Of the 19 countries reporting on FOR in 2008, Italy is by far the country with the most cycles using this technology," said Dr. Jacques de Mouzon, chair of the EIM. With 3,284 cycles, Italy is far ahead of Finland (325 cycles), Russia (220) and Spain (199). The reason for Italy's dominance in this area lies in its legislative framework. A law passed in 2004 and overruled in 2009, set a limit of three oocytes to be inseminated per cycle, of which all resulting embryos had to be transferred. Embryo freezing and research on the embryo was outlawed, but not egg freezing. Hence, Italian clinics gained considerable expertise in this area over the last years.

The group also reported that with 4,068 cycles, 30 % of all egg donations (ED) occur in Spain, followed by the Czech Republic (15 %) and Russia (12 %). "Three countries make up almost 60 % of all egg donations in Europe," said Dr. De Mouzon. "Certain clinics in Spain offer wide-ranging egg donation programmes, which may also be the reason why Spain scores so high in terms of frozen oocyte cycles." This fact is mostly due to restrictive laws on ED in many countries, leading to many couples to cross borders to countries with less restrictive laws, which has raised an ethical and public health problem.

During the same scientific session, Dr. Karl Nygren, chair of ICMART, presented global ART data for 2007. "We are particularly pleased to present our data in Stockholm this year, since we can show that Sweden, a pioneer in enforcing single embryo transfer, has the world's lowest multiple birth rate with only 7 % twins and 0.1% of triplets being born after IVF and ICSI." Only Finland and Australia show comparably low rates with 9.3 % and 8.4% of twins, respectively, and almost no triplets. Many countries are still above 20 % for twin deliveries following IVF or ICSI such as for example Spain (23.8 %), Italy (21.2 %) and Germany (21.1 %) as are many Eastern European countries. "We would like to see more countries follow suit to decrease long-term complications for mother and child." The average rate in Europe was 20.6 % for twins and 1.1% for triplets in Europe.

According to data presented by the European IVF Monitoring Group (EIM), 525,640 treatment cycles were reported in 36 European countries. Four more countries reported in 2008 compared to 2007. This compares globally with 148,055 cycles from the US and 61,929 cycles from Australia and New Zealand. "We observed a 9.7 % increase in the number of cycles in Europe from 2007 to 2008, with only 21 more clinics reporting to our database," said Dr. Jacques de Mouzon, chairman of ESHRE's EIM. The delivery rate (DR) per aspiration was 22.1% for IVF and 21.1% for ICSI. DR per transfer was 14.5% for FET and 28.5% for ED. All these rates were relatively stable compared to the previous year, as was the multiple deliveries proportion.

In 30 countries where clinics reported deliveries, 80,284 babies were born. "We believe this to be an underestimate since data on deliveries for Turkey, Poland and some other countries were still missing." There were 124,749 IVF treatments, 280,977 intracytoplasmic sperm injection (ICSI) cycles, 98,288 frozen embryo transfer cycles (FER), 13,609 egg donor cycles (ED), 4,080 FOR, 2,875 preimplantation genetic diagnosis/screening cycles (PGD/PGS) and 1,062 in vitro maturation cycles (IVM).

In terms of ART availability, the largest economies in Europe such as France (5,464 cycles per million women of reproductive age), Italy (4,015), Spain (3,845), the Netherlands (6,382), Germany (4,810) and the UK (4,066) still show much lower availabilities of ART compared to their Nordic neighbours such as Sweden (9,228), Norway (9,287), Denmark (12,712) and Finland (9,291). This is also mirrored in the number of infants born after ART with only 1.7 % in Spain, 2.4 % in the Netherlands, 1.4 % in Germany and 1.9 % in the UK compared to 3.3 % in Sweden, 2.4 % in Norway and 3.0 % in Finland. For Denmark figures were not available yet. Also, 25 countries reported 146,741 IUI-H (with husband's sperm) and 24, 895 IUI-D (donor sperm), with a multiple pregnancy rate (11.1% twin and 0.8 triplet for women aged less than 40 years) not higher than in IVF and ICSI.


Story Source:

The above story is based on materials provided by European Society of Human Reproduction and Embryology. Note: Materials may be edited for content and length.


Cite This Page:

European Society of Human Reproduction and Embryology. "For the first time, the European IVF Monitoring Group reports on cycles using frozen eggs." ScienceDaily. ScienceDaily, 6 July 2011. <www.sciencedaily.com/releases/2011/07/110706093713.htm>.
European Society of Human Reproduction and Embryology. (2011, July 6). For the first time, the European IVF Monitoring Group reports on cycles using frozen eggs. ScienceDaily. Retrieved September 19, 2014 from www.sciencedaily.com/releases/2011/07/110706093713.htm
European Society of Human Reproduction and Embryology. "For the first time, the European IVF Monitoring Group reports on cycles using frozen eggs." ScienceDaily. www.sciencedaily.com/releases/2011/07/110706093713.htm (accessed September 19, 2014).

Share This



More Health & Medicine News

Friday, September 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Cost of Ebola

The Cost of Ebola

Reuters - Business Video Online (Sep. 18, 2014) As Sierra Leone prepares for a three-day "lockdown" in its latest bid to stem the spread of Ebola, Ciara Lee looks at the financial implications of fighting the largest ever outbreak of the disease. Video provided by Reuters
Powered by NewsLook.com
What HealthKit Bug Means For Your iOS Fitness Apps

What HealthKit Bug Means For Your iOS Fitness Apps

Newsy (Sep. 18, 2014) Apple has delayed the launch of the HealthKit app platform, citing a bug. Video provided by Newsy
Powered by NewsLook.com
U.S. Food Makers Surpass Calorie-Cutting Pledge

U.S. Food Makers Surpass Calorie-Cutting Pledge

Newsy (Sep. 18, 2014) Sixteen large food and beverage companies in the United States that committed to cut calories in their products far surpassed their target. Video provided by Newsy
Powered by NewsLook.com
Residents Vaccinated as Haiti Fights Cholera Epidemic

Residents Vaccinated as Haiti Fights Cholera Epidemic

AFP (Sep. 18, 2014) Haitians receive the second dose of the vaccine against cholera as part of the UN's vaccination campaign. Duration: 00:34 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins