Featured Research

from universities, journals, and other organizations

HPV infection highly prevalent among organ transplant recipients, study reveals

Date:
July 12, 2011
Source:
Wiley-Blackwell
Summary:
A new study reveals an association between the human papillomavirus (betaPV) infection and cutaneous squamous cell carcinoma (SCC) in organ transplant recipients.

A new study published in the American Journal of Transplantation reveals an association between the human papillomavirus (betaPV) infection and cutaneous squamous cell carcinoma (SCC) in organ transplant recipients.

Related Articles


HPV is known to cause cervical cancer and SCC in the anogenital area and also plays a role in some forms of head and neck cancer. SCC skin cancer is increasing in incidence worldwide and the risk is particularly high in immunosuppressed individuals such as organ transplant recipients in whom rates are 100 times those of the general population.

Researchers led by Jan Nico Bouwes Bavinck and Mariet Feltkamp of Leiden University Medical Center, studied a total of 210 organ transplant recipients with previous SCC and 394 controls without skin cancer. They used cutting-edge technologies to assess the presence of 25 betaPV types in plucked eyebrow hairs with simultaneous detection of antibodies to these viruses in blood.

Results show that BetaPV infection is highly prevalent in organ transplant recipients; 94% of patients without skin cancers carried DNA in eyebrow hairs and 97% in those with a history of skin cancer. Furthermore, concordant presence of DNA and antibodies to the same beta HPV type is associated with increased risk for SCC skin cancer.

"Carriage of beta HPV types (a particular skin group of HPV viruses) is extremely common in immunosuppressed individuals," Feltkamp notes. "Our research findings help to provide a clearer picture of the specific HPV types that may play a part in causing SCC which ultimately may lead to novel preventative or therapeutic interventions."


Story Source:

The above story is based on materials provided by Wiley-Blackwell. Note: Materials may be edited for content and length.


Journal Reference:

  1. C. M. Proby, C. A. Harwood, R. E. Neale, A. C. Green, S. Euvrard, L. Naldi, G. Tessari, M. C. W. Feltkamp, M. N. C. de Koning, W. G. V. Quint, T. Waterboer, M. Pawlita, S. Weissenborn, U. Wieland, H. Pfister, E. Stockfleth, I. Nindl, D. Abeni, J. ter Schegget, J. N. Bouwes Bavinck. A Case-Control Study of Betapapillomavirus Infection and Cutaneous Squamous Cell Carcinoma in Organ Transplant Recipients. American Journal of Transplantation, 2011; 11 (7): 1498 DOI: 10.1111/j.1600-6143.2011.03589.x

Cite This Page:

Wiley-Blackwell. "HPV infection highly prevalent among organ transplant recipients, study reveals." ScienceDaily. ScienceDaily, 12 July 2011. <www.sciencedaily.com/releases/2011/07/110712102320.htm>.
Wiley-Blackwell. (2011, July 12). HPV infection highly prevalent among organ transplant recipients, study reveals. ScienceDaily. Retrieved March 31, 2015 from www.sciencedaily.com/releases/2011/07/110712102320.htm
Wiley-Blackwell. "HPV infection highly prevalent among organ transplant recipients, study reveals." ScienceDaily. www.sciencedaily.com/releases/2011/07/110712102320.htm (accessed March 31, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Tuesday, March 31, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

7-Year-Old Girl Gets 3-D Printed 'robohand'

7-Year-Old Girl Gets 3-D Printed 'robohand'

AP (Mar. 31, 2015) — Although she never had much interest in prosthetic limbs before, Faith Lennox couldn&apos;t wait to slip on her new robohand. The 7-year-old, who lost part of her left arm when she was a baby, grabbed it as soon as it came off a 3-D printer. (March 31) Video provided by AP
Powered by NewsLook.com
Solitair Device Aims to Takes Guesswork out of Sun Safety

Solitair Device Aims to Takes Guesswork out of Sun Safety

Reuters - Innovations Video Online (Mar. 31, 2015) — The Solitair device aims to take the confusion out of how much sunlight we should expose our skin to. Small enough to be worn as a tie or hair clip, it monitors the user&apos;s sun exposure by taking into account their skin pigment, location and schedule. Matthew Stock reports. Video provided by Reuters
Powered by NewsLook.com
Soda, Salt and Sugar: The Next Generation of Taxes

Soda, Salt and Sugar: The Next Generation of Taxes

Washington Post (Mar. 30, 2015) — Denisa Livingston, a health advocate for the Dinι Community Advocacy Alliance, and the Post&apos;s Abby Phillip discuss efforts around the country to make unhealthy food choices hurt your wallet as much as your waistline. Video provided by Washington Post
Powered by NewsLook.com
UnitedHealth Buys Catamaran

UnitedHealth Buys Catamaran

Reuters - Business Video Online (Mar. 30, 2015) — The $12.8 billion merger will combine the U.S.&apos; third and fourth largest pharmacy benefit managers. Analysts say smaller PBMs could also merge. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins