Featured Research

from universities, journals, and other organizations

No strong evidence to support aspirin use for IVF

Date:
August 10, 2011
Source:
Wiley-Blackwell
Summary:
A systematic review did not find compelling evidence to support the routine use of aspirin in women being treated for IVF. The researchers reported that taking aspirin during an IVF cycle did not seem to increase a woman's chances of becoming pregnant.

A systematic review published in The Cochrane Library did not find compelling evidence to support the routine use of aspirin in women being treated for IVF. The researchers reported that taking aspirin during an IVF cycle did not seem to increase a woman's chances of becoming pregnant.

The use of aspirin during IVF treatment is controversial. Part of the thinking behind any potential benefit is that aspirin may improve the blood flow to the womb and ovaries. However, there are also concerns that taking aspirin may cause miscarriage or complications in pregnancy.

The latest review is an update of a Cochrane Systematic Review published in 2007. The researchers added evidence from new trials giving a total of 13 that together involved 2,653 women. All women were undergoing IVF and in most cases, aspirin was taken as a 100 mg dose once a day. Although one large study suggested some benefit associated with taking aspirin, the overall conclusion was that there was no evidence that aspirin would improve a woman's chances of conceiving compared to placebo. Large trials showing beneficial effects would now be needed to change these conclusions, according to the researchers.

"Couples undergoing IVF often feel so desperate that they are prepared to try anything that may improve their chances of conceiving," said lead researcher Charalambos Siristatidis of the Assisted Reproduction Unit at the University of Athens in Greece. "But given the current evidence, there is still no basis to recommend that women take aspirin to help them become pregnant."

The researchers had looked primarily for trials that used live births as a measure of effectiveness, but only three reported this information. Instead, most studies reported pregnancies and the number of women who became pregnant in the group given aspirin was about the same as in group given placebos. Five studies reported miscarriage rate and found no difference between those taking aspirin and those taking placebos.

"It was disappointing to see that so few of the studies reported live birth rate as this is ultimately the outcome all couples undergoing IVF are interested in," said Siristatidis. "The lack of information on miscarriage rate is also concerning given previous studies that have linked higher doses of aspirin to miscarriage."


Story Source:

The above story is based on materials provided by Wiley-Blackwell. Note: Materials may be edited for content and length.


Cite This Page:

Wiley-Blackwell. "No strong evidence to support aspirin use for IVF." ScienceDaily. ScienceDaily, 10 August 2011. <www.sciencedaily.com/releases/2011/08/110809212427.htm>.
Wiley-Blackwell. (2011, August 10). No strong evidence to support aspirin use for IVF. ScienceDaily. Retrieved August 29, 2014 from www.sciencedaily.com/releases/2011/08/110809212427.htm
Wiley-Blackwell. "No strong evidence to support aspirin use for IVF." ScienceDaily. www.sciencedaily.com/releases/2011/08/110809212427.htm (accessed August 29, 2014).

Share This




More Health & Medicine News

Friday, August 29, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Killer Amoeba Found in Louisiana Water System

Killer Amoeba Found in Louisiana Water System

AP (Aug. 28, 2014) — State health officials say testing has confirmed the presence of a killer amoeba in a water system serving three St. John the Baptist Parish towns. (Aug. 28) Video provided by AP
Powered by NewsLook.com
Who Could Be Burnt by WHO's E-Cigs Move?

Who Could Be Burnt by WHO's E-Cigs Move?

Reuters - Business Video Online (Aug. 28, 2014) — The World Health Organisation has called for the regulation of electronic cigarettes as both tobacco and medical products. Ciara Lee looks at the impact of the move on the tobacco industry. Video provided by Reuters
Powered by NewsLook.com
CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

Newsy (Aug. 28, 2014) — CDC director Tom Frieden says the Ebola outbreak is even worse than he feared. But he also said there's still hope to contain it. Video provided by Newsy
Powered by NewsLook.com
How A 'Rule Of Thumb' Could Slow Down Drinking

How A 'Rule Of Thumb' Could Slow Down Drinking

Newsy (Aug. 28, 2014) — A study suggests people who follow a "rule of thumb" when pouring wine dispense less than those who don't have a particular amount in mind. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins