Featured Research

from universities, journals, and other organizations

No strong evidence to support aspirin use for IVF

Date:
August 10, 2011
Source:
Wiley-Blackwell
Summary:
A systematic review did not find compelling evidence to support the routine use of aspirin in women being treated for IVF. The researchers reported that taking aspirin during an IVF cycle did not seem to increase a woman's chances of becoming pregnant.

A systematic review published in The Cochrane Library did not find compelling evidence to support the routine use of aspirin in women being treated for IVF. The researchers reported that taking aspirin during an IVF cycle did not seem to increase a woman's chances of becoming pregnant.

Related Articles


The use of aspirin during IVF treatment is controversial. Part of the thinking behind any potential benefit is that aspirin may improve the blood flow to the womb and ovaries. However, there are also concerns that taking aspirin may cause miscarriage or complications in pregnancy.

The latest review is an update of a Cochrane Systematic Review published in 2007. The researchers added evidence from new trials giving a total of 13 that together involved 2,653 women. All women were undergoing IVF and in most cases, aspirin was taken as a 100 mg dose once a day. Although one large study suggested some benefit associated with taking aspirin, the overall conclusion was that there was no evidence that aspirin would improve a woman's chances of conceiving compared to placebo. Large trials showing beneficial effects would now be needed to change these conclusions, according to the researchers.

"Couples undergoing IVF often feel so desperate that they are prepared to try anything that may improve their chances of conceiving," said lead researcher Charalambos Siristatidis of the Assisted Reproduction Unit at the University of Athens in Greece. "But given the current evidence, there is still no basis to recommend that women take aspirin to help them become pregnant."

The researchers had looked primarily for trials that used live births as a measure of effectiveness, but only three reported this information. Instead, most studies reported pregnancies and the number of women who became pregnant in the group given aspirin was about the same as in group given placebos. Five studies reported miscarriage rate and found no difference between those taking aspirin and those taking placebos.

"It was disappointing to see that so few of the studies reported live birth rate as this is ultimately the outcome all couples undergoing IVF are interested in," said Siristatidis. "The lack of information on miscarriage rate is also concerning given previous studies that have linked higher doses of aspirin to miscarriage."


Story Source:

The above story is based on materials provided by Wiley-Blackwell. Note: Materials may be edited for content and length.


Cite This Page:

Wiley-Blackwell. "No strong evidence to support aspirin use for IVF." ScienceDaily. ScienceDaily, 10 August 2011. <www.sciencedaily.com/releases/2011/08/110809212427.htm>.
Wiley-Blackwell. (2011, August 10). No strong evidence to support aspirin use for IVF. ScienceDaily. Retrieved October 24, 2014 from www.sciencedaily.com/releases/2011/08/110809212427.htm
Wiley-Blackwell. "No strong evidence to support aspirin use for IVF." ScienceDaily. www.sciencedaily.com/releases/2011/08/110809212427.htm (accessed October 24, 2014).

Share This



More Health & Medicine News

Friday, October 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) — IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) — A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com
WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) — The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com
Doctor in NYC Quarantined With Ebola

Doctor in NYC Quarantined With Ebola

AP (Oct. 24, 2014) — An emergency room doctor who recently returned to the city after treating Ebola patients in West Africa has tested positive for the virus. He's quarantined in a hospital. (Oct. 24) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins