Featured Research

from universities, journals, and other organizations

Researchers find increase in infection rates in patients with cardiac electrophysiological devices

Date:
August 22, 2011
Source:
Thomas Jefferson University
Summary:
New research shows that patients in the United States who receive cardiac electrophysiological devices (CIEDs), including permanent pacemakers and implantable cardioverter-defibrillators (ICDs) are now at greater risk of contracting an infection over the life span of the device.

New research from the Jefferson Heart Institute shows that patients in the United States who receive cardiac electrophysiological devices (CIEDs), including permanent pacemakers and implantable cardioverter-defibrillators (ICDs) are now at greater risk of contracting an infection over the life span of the device.

Related Articles


Jefferson, in collaboration with researchers from Drexel University School of Biomedical Engineering and engineering and consulting firm Exponent, analyzed data from the Nationwide Inpatient Sample -- a national database of hospital discharge records -- from 1993-2008 and found a significant increase in CIED-related infections. Their findings are published in the August 30 issue of the Journal of the American College of Cardiology.

Their analysis found that the annual incidence of CIED-related infection increased by 210 percent over the 16-year period studied.

Further analysis showed a jump in infections after 2004, directly correlating with an increase in four major comorbidities: renal failure, respiratory failure, heart failure and diabetes.

"We believe the growing number of clinical comorbidities in this patient population plays a large role in the increase in infections associated with CIEDs," said Arnold J. Greenspon, M.D., professor of medicine at Jefferson Medical College of Thomas Jefferson University, director of Cardiac Electrophysiology at Thomas Jefferson University Hospital, and lead author of the study. "The patients are sicker, which may place them at higher risk for infection." The highest infection rates occurred in white males over 65.

Pacemakers and ICDs are important in regulating the electrical signaling to the heart. Pacemakers help to speed up a slow heart rhythm (bradycardia) whereas ICDs help to slow down rapid heart rhythm (tachycardia), a potentially life-threatening condition.

The study showed a 96 percent increase in CIED implantation, mostly due to a marked increase in the use of ICDs. "The expanding indications for ICD implantation may have contributed to the rise in infections since many of these patients have multiple medical co-morbidities," added Dr. Greenspon.

"The number of Americans receiving pacemakers and defibrillators has dramatically increased. This analysis shows that the infection risk associated with these devices has, unfortunately, increased as well," said Greenspon. A better understanding of the risk factors for infection will improve patient care and, hopefully, reduce the prolonged hospital stays that often result.

Rising CIED infection rates also have economic implications for hospitals, as these patients require prolonged hospital stays which are associated with increased costs.

Further investigation into the risk factors that predict CIED infection or therapies to mitigate this issue is warranted.

Other authors include Daniel R. Frisch, MD, assistant professor of Medicine and director of Jefferson's Atrial Fibrillation program; Reginald T. Ho, MD, clinical assistant professor of Cardiology; and Behzad B. Pavri, MD, associate professor of Cardiology.


Story Source:

The above story is based on materials provided by Thomas Jefferson University. Note: Materials may be edited for content and length.


Journal Reference:

  1. Greenspon, Arnold J., Patel, Jasmine D., Lau, Edmund, Ochoa, Jorge A., Frisch, Daniel R., Ho, Reginald T., Pavri, Behzad B., Kurtz, Steven M. 16-Year Trends in the Infection Burden for Pacemakers and Implantable Cardioverter-Defibrillators in the United States: 1993 to 2008. J Am Coll Cardiol, 2011 58: 1001-1006 DOI: 10.1016/j.jacc.2011.04.033

Cite This Page:

Thomas Jefferson University. "Researchers find increase in infection rates in patients with cardiac electrophysiological devices." ScienceDaily. ScienceDaily, 22 August 2011. <www.sciencedaily.com/releases/2011/08/110822161340.htm>.
Thomas Jefferson University. (2011, August 22). Researchers find increase in infection rates in patients with cardiac electrophysiological devices. ScienceDaily. Retrieved December 22, 2014 from www.sciencedaily.com/releases/2011/08/110822161340.htm
Thomas Jefferson University. "Researchers find increase in infection rates in patients with cardiac electrophysiological devices." ScienceDaily. www.sciencedaily.com/releases/2011/08/110822161340.htm (accessed December 22, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, December 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Touch-Free Smart Phone Empowers Mobility-Impaired

Touch-Free Smart Phone Empowers Mobility-Impaired

Reuters - Innovations Video Online (Dec. 21, 2014) A touch-free phone developed in Israel enables the mobility-impaired to operate smart phones with just a movement of the head. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Earthworms Provide Cancer-Fighting Bacteria

Earthworms Provide Cancer-Fighting Bacteria

Reuters - Innovations Video Online (Dec. 21, 2014) Polish scientists isolate bacteria from earthworm intestines which they say may be used in antibiotics and cancer treatments. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Existing Chemical Compounds Could Revive Failing Antibiotics, Says Danish Scientist

Existing Chemical Compounds Could Revive Failing Antibiotics, Says Danish Scientist

Reuters - Innovations Video Online (Dec. 21, 2014) A team of scientists led by Danish chemist Jorn Christensen says they have isolated two chemical compounds within an existing antipsychotic medication that could be used to help a range of failing antibiotics work against killer bacterial infections, such as Tuberculosis. Jim Drury went to meet him. Video provided by Reuters
Powered by NewsLook.com
Hugging It Out Could Help You Ward Off A Cold

Hugging It Out Could Help You Ward Off A Cold

Newsy (Dec. 21, 2014) Carnegie Mellon researchers found frequent hugs can help people avoid stress-related illnesses. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins