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Misunderstanding surrounds HIV vaccine trials: Study shows better communication needed with at-risk communities

Date:
September 6, 2011
Source:
University of Toronto
Summary:
Better communication is needed around HIV vaccine trials to ensure those in at-risk communities understand the process and continue to participate, according to a new study.

Better communication is needed around HIV vaccine trials to ensure those in at-risk communities understand the process and continue to participate, according to a new University of Toronto study.

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The study -- published in the September edition of the American Journal of Public Health -- centred around a major international HIV vaccine trial that was called off before completion in 2009. Researchers wanted to know what individuals in high-risk communities understood about the trial and its termination, and how that impacted their willingness to participate in and support future research.

"In order to find a vaccine for HIV, it's essential to have the participation of those in at-risk communities for vaccine trials," says lead author Peter A. Newman, Professor at U of T's Factor-Inwentash Faculty of Social Work. "Our study showed that we're not doing enough to adequately communicate the processes and outcomes of HIV vaccine trials to most-at-risk populations. There is still a lot of misinformation, distrust and misunderstanding out there, which could ultimately lead to people in high-risk communities refusing to participate in trials."

In Toronto and Ottawa, researchers interviewed nine focus groups made up of people from "high-risk" communities. They asked participants about their knowledge of vaccines and vaccine trials -- including the cancelled international trial -- and probed their understanding of why that trial was called off. Researchers also questioned participants about their willingness to participate in future trials.

A few key themes emerged, according to Newman, who holds the Canada Research Chair in Health and Social Justice at U of T:

  • Many people still believe that vaccine trials involve injecting a small amount of HIV into participants, a falsehood that could affect their willingness to participate in vaccine trials.
  • There is a distrust of doctors and medical researchers. The international vaccine trial was called off when researchers discovered a small subset of participants were placed at a higher risk of contracting HIV, but many people didn't believe this was an unforeseen consequence. Some participants believed the doctors/researchers must have been able to predict this consequence, and this reinforced their distrust in the medical system.
  • There is some confusion surrounding why HIV vaccine trials target people in high-risk communities. Some study participants saw this as unfair, from a social justice perspective.

"We found that there is a general altruism towards HIV vaccine trials in these communities, and a feeling that people should participate 'for the greater good,'" says Newman. "But there is also a lot of overriding confusion and misunderstanding, which illustrates a clear need for medical researchers and health professionals to do a better job of communicating with at-risk communities before, during and after trials."

Newman will present related findings at this year's annual AIDS Vaccine Conference in Bangkok between September 12 to 15.


Story Source:

The above story is based on materials provided by University of Toronto. The original article was written by April Kemick. Note: Materials may be edited for content and length.


Journal Reference:

  1. P. A. Newman, C. Logie, L. James, T. Charles, J. Maxwell, K. Salam, M. Woodford. 'Speaking the Dialect': Understanding Public Discourse in the Aftermath of an HIV Vaccine Trial Shutdown. American Journal of Public Health, 2011; 101 (9): 1749 DOI: 10.2105/AJPH.2011.300208

Cite This Page:

University of Toronto. "Misunderstanding surrounds HIV vaccine trials: Study shows better communication needed with at-risk communities." ScienceDaily. ScienceDaily, 6 September 2011. <www.sciencedaily.com/releases/2011/09/110906134005.htm>.
University of Toronto. (2011, September 6). Misunderstanding surrounds HIV vaccine trials: Study shows better communication needed with at-risk communities. ScienceDaily. Retrieved March 29, 2015 from www.sciencedaily.com/releases/2011/09/110906134005.htm
University of Toronto. "Misunderstanding surrounds HIV vaccine trials: Study shows better communication needed with at-risk communities." ScienceDaily. www.sciencedaily.com/releases/2011/09/110906134005.htm (accessed March 29, 2015).

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