Featured Research

from universities, journals, and other organizations

Evaluation of pediatric psoriasis outpatient health care delivery finds some treatment variability

Date:
September 19, 2011
Source:
JAMA and Archives Journals
Summary:
Most outpatient visits for pediatric psoriasis in the United States are made by white children ages 8 years and older and are made to dermatologists and pediatricians, but the treatment approach may differ by physician specialty and patient age, according to a new study.

Most outpatient visits for pediatric psoriasis in the United States are made by white children ages 8 years and older and are made to dermatologists and pediatricians, but the treatment approach may differ by physician specialty and patient age, according to a report published Online First by Archives of Dermatology, one of the JAMA/Archives journals.

According to background information in the article, approximately 2.5 percent of the U.S. population is affected by psoriasis, including 1 percent of children from birth to 18 years. In one-third of patients, the first signs and symptoms appear by the age of 20 years. Clinicians consider disease severity, presentation and distribution of lesions, patient age and the presence of concurrent conditions in determining treatment. For mild, localized cases in the pediatric population, topical medications are generally used, with phototherapy and systemic medication usually utilized for more complex cases. "Management of psoriasis in children can be challenging," write the authors, "owing to a paucity of data and lack of standardized guidelines specific to the pediatric population."

Sinae A. Vogel, B.S., from the University of California, San Francisco School of Medicine, and colleagues conducted a retrospective, cross-sectional investigation of data from the National Ambulatory Medical Care Survey. The authors examined outpatient-visit data from dermatologists and nondermatologists from 1979 to 2007 (except the periods 1982-1984 and 1987-1988, when data were not collected) for pediatric visits (children ages 0 to 18 years) with a diagnosis of psoriasis. The researchers tabulated the frequency of medications in the database and assigned them to three categories: topical corticosteroid, topical noncorticosteroid and systemic. Corticosteroids were further assigned a relative potency value from one (super potent) to seven (very weak).

In total, an estimated 3.8 million pediatric psoriasis visits occurred during the 28-year interval, with a median (midpoint) of 123,420 visits per year. Nearly two-thirds of patients visited dermatologists for the condition (63 percent); 17 percent of psoriasis visits were made to pediatricians and 14 percent were made to internists. Equal numbers of visits were made by male and female patients, 93 percent of whom were white. Patients ages 13 to 18 years made 47 percent of the visits, children ages 8 to 12 years made 35 percent of the visits and those ages 0 to 7 years made 18 percent of the visits.

The most commonly prescribed medications were topical corticosteroids, and the potency levels of these medications appeared equal in younger and older children. Overall, and in both younger and older age groups, the most commonly prescribed medication was the topical corticosteroid betamethasone. Dermatologists and internists most commonly prescribed high-potency steroids, and pediatricians most commonly prescribed the topical immunosuppressant tacrolimus. The top 20 most-prescribed medications by dermatologists did not include topical calcineurin inhibitors (medications that prevent inflammation), and the top 20 most-prescribed medications in any age group did not include systemic antipsoriatic agents.

"This study confirms that pediatric psoriasis visits are frequent and represent a substantial burden of disease in the United States, validating the social, economic, and medical impact of this disease," write the authors. They note the age differences in office visits for the condition as well as the trends in medication usage, and are particularly concerned about the frequency of strong corticosteroid use in patients younger than 8 years. "In our experience, the highest potency topical corticosteroids are not commonly needed for psoriasis in young children," the researchers state.

Such trends appear to point to a need for treatment guidelines that address the condition in children. "The current state-of-the-art care for pediatric psoriasis is based primarily on experience and expert consensus," and some clinicians may not be anticipated to change even if standardized treatment guidelines existed, write the authors. "As such, education of our dermatology and nondermatology colleagues about unique clinical and treatment aspects of pediatric psoriasis, rather than guidelines alone, may decrease the treatment gap by creating more comfortable, safe, and effective use of topical and systemic regimens for children with psoriasis."


Story Source:

The above story is based on materials provided by JAMA and Archives Journals. Note: Materials may be edited for content and length.


Journal Reference:

  1. Sinae A. Vogel; Brad Yentzer; Scott A. Davis; Steven R. Feldman; Kelly M. Cordoro. Trends in Pediatric Psoriasis Outpatient Health Care Delivery in the United States. Archives of Dermatology, 2011; DOI: 10.1001/archdermatol.2011.263

Cite This Page:

JAMA and Archives Journals. "Evaluation of pediatric psoriasis outpatient health care delivery finds some treatment variability." ScienceDaily. ScienceDaily, 19 September 2011. <www.sciencedaily.com/releases/2011/09/110919164006.htm>.
JAMA and Archives Journals. (2011, September 19). Evaluation of pediatric psoriasis outpatient health care delivery finds some treatment variability. ScienceDaily. Retrieved July 23, 2014 from www.sciencedaily.com/releases/2011/09/110919164006.htm
JAMA and Archives Journals. "Evaluation of pediatric psoriasis outpatient health care delivery finds some treatment variability." ScienceDaily. www.sciencedaily.com/releases/2011/09/110919164006.htm (accessed July 23, 2014).

Share This




More Health & Medicine News

Wednesday, July 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com
Why Do People Believe We Only Use 10 Percent Of Our Brains?

Why Do People Believe We Only Use 10 Percent Of Our Brains?

Newsy (July 22, 2014) The new sci-fi thriller "Lucy" is making people question whether we really use all our brainpower. But, as scientists have insisted for years, we do. Video provided by Newsy
Powered by NewsLook.com
Scientists Find New Way To Make Human Platelets

Scientists Find New Way To Make Human Platelets

Newsy (July 22, 2014) Boston scientists have discovered a new way to create fully functioning human platelets using a bioreactor and human stem cells. Video provided by Newsy
Powered by NewsLook.com
Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins