Featured Research

from universities, journals, and other organizations

Polymeric material has potential for noninvasive procedures

Date:
October 3, 2011
Source:
University of California - San Diego
Summary:
Scientists have developed what they believe to be the first polymeric material that is sensitive to biologically benign levels of near infrared irradiation, enabling the material to disassemble in a highly controlled fashion. The study represents a significant milestone in the area of light-sensitive material for non-invasive medical and biological applications.

Scientists at the University of California, San Diego have developed what they believe to be the first polymeric material that is sensitive to biologically benign levels of near infrared (NRI) irradiation, enabling the material to disassemble in a highly controlled fashion. The study represents a significant milestone in the area of light-sensitive material for non-invasive medical and biological applications.

Their work is published online this week in the journal Macromolecules.

"To the best of our knowledge, this is the only polymeric material specifically designed to break down in to small fragments in response to very low levels of NIR irradiation," said Adah Almutairi, PhD, assistant professor at the UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences and director of the Laboratory of Bioresponsive Materials at UC San Diego. "The material was also shown to be well-tolerated in cells before and after irradiation. We think there is great potential for use in human patients, allowing previously inaccessible targets sites to be reached for both treatment and diagnosis."

The properties of so-called "smart" polymeric materials -- either synthetic or natural -- respond readily to small changes in their environment. They are, therefore, the focus of widespread research to develop tools for such uses as tissue engineering, implants, wound-healing, drug delivery and biosensors.

NIR light can penetrate up to 10 cm into tissue with less damage, absorption and scattering than visible light, and can be remotely applied with high spatial and temporal precision. Most other light-degradable materials that have been developed to date can be difficult to clear from the body, and only a handful of organic materials respond to high-power NIR light. Until now, none were able to respond to low-level, thus safer, NIR light -- which causes less photodamage to tissue and cells.

The UC San Diego researchers stated that further studies are warranted to improve the sensitivity of these smart polymeric materials to NIR, and they are currently pursuing several synthetic and engineering strategies to improve design of such biomaterials.

Additional researchers include Nadezda Fomina, Cathryn L. McFearin, Marleen Sermsakdi, and José M. Morachis, Skaggs School of Pharmacy, Department of NanoEngineering at the Jacobs School of Engineering, Materials Science and Engineering and Biomedical Sciences Programs, UC San Diego.

Funding was provided by an NIH Directors New Innovator Award and King Abdul Aziz City of Science and Technology support.


Story Source:

The above story is based on materials provided by University of California - San Diego. The original article was written by Debra Kain. Note: Materials may be edited for content and length.


Journal Reference:

  1. Nadezda Fomina, Cathryn L. McFearin, Marleen Sermsakdi, José M. Morachis, Adah Almutairi. Low Power, Biologically Benign NIR Light Triggers Polymer Disassembly. Macromolecules, 2011; 110930161124006 DOI: 10.1021/ma201850q

Cite This Page:

University of California - San Diego. "Polymeric material has potential for noninvasive procedures." ScienceDaily. ScienceDaily, 3 October 2011. <www.sciencedaily.com/releases/2011/10/111003132445.htm>.
University of California - San Diego. (2011, October 3). Polymeric material has potential for noninvasive procedures. ScienceDaily. Retrieved July 22, 2014 from www.sciencedaily.com/releases/2011/10/111003132445.htm
University of California - San Diego. "Polymeric material has potential for noninvasive procedures." ScienceDaily. www.sciencedaily.com/releases/2011/10/111003132445.htm (accessed July 22, 2014).

Share This




More Matter & Energy News

Tuesday, July 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Government Approves East Coast Oil Exploration

Government Approves East Coast Oil Exploration

AP (July 18, 2014) — The Obama administration approved the use of sonic cannons to discover deposits under the ocean floor by shooting sound waves 100 times louder than a jet engine through waters shared by endangered whales and turtles. (July 18) Video provided by AP
Powered by NewsLook.com
Sunken German U-Boat Clearly Visible For First Time

Sunken German U-Boat Clearly Visible For First Time

Newsy (July 18, 2014) — The wreckage of the German submarine U-166 has become clearly visible for the first time since it was discovered in 2001. Video provided by Newsy
Powered by NewsLook.com
Obama: U.S. Must Have "smartest Airports, Best Power Grid"

Obama: U.S. Must Have "smartest Airports, Best Power Grid"

Reuters - US Online Video (July 17, 2014) — President Barak Obama stopped by at a lunch counter in Delaware before making remarks about boosting the nation's infrastructure. Mana Rabiee reports. Video provided by Reuters
Powered by NewsLook.com
Crude Oil Prices Bounce Back After Falling Below $100 a Barrel

Crude Oil Prices Bounce Back After Falling Below $100 a Barrel

TheStreet (July 16, 2014) — Oil Futures are bouncing back after tumbling below $100 a barrel for the first time since May yesterday. Jeff Grossman is the president of BRG Brokerage and trades at the NYMEX. Grossman tells TheStreet the Middle East is always a concern for oil traders. Oil prices were pushed down in recent weeks on Libya increasing its production. Supply disruptions in Iraq fading also contributed to prices falling. News from China's economic front showing a growth for the second quarter also calmed fears on its slowdown. Jeff Grossman talks to TheStreet's Susannah Lee on this and more on the Energy Department's Energy Information Administration (EIA) report. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins