Featured Research

from universities, journals, and other organizations

Spinal cord injuries associated with increased risk of heart disease, study finds

Date:
October 24, 2011
Source:
Heart and Stroke Foundation of Canada
Summary:
New research may help explain why people with spinal cord injury (SCI) have a higher risk of developing heart disease.

New research from the Heart and Stroke Foundation and the Christopher and Dana Reeve Foundation may help explain why people with spinal cord injury (SCI) have a higher risk of developing heart disease.

Damage to the autonomic nervous system is a key predictor of cardiovascular risk, researcher Rianne Ravensbergen told the Canadian Cardiovascular Congress 2011, co-hosted by the Heart and Stroke Foundation and the Canadian Cardiovascular Society.

Heart disease after a SCI is the leading cause of morbidity and mortality in this population. It is well known that regular exercise is beneficial for cardiovascular health. However, for people with SCI, says Ravensbergen, a PhD candidate supervised by Dr. Victoria Claydon in the cardiovascular physiology laboratory at Simon Fraser University, exercise is only part of the story. "In this specific group we should also be looking at whether they have autonomic dysfunction, because this causes a higher risk for heart disease."

The autonomic system controls functions of the body that are automatic, or involuntary -- such as activities of the bladder, bowel, gastrointestinal tract, liver, heart, and blood vessels. After SCI the autonomic nerves in the spinal cord can be damaged, leading to widespread abnormalities in autonomic function, and, of particular relevance to Ravensbergen's work, abnormal control of the heart and blood vessels.

Cardiovascular disease accounts for 30 percent of all deaths in Canada. For those with spinal cord injury -- almost 85,000 Canadians -- heart disease tends to develop earlier in life, even in those with a healthy lifestyle. "In people with autonomic dysfunction due to SCI, they may remain at high risk of cardiovascular disease, even if they maintain a healthy lifestyle and exercise regularly," says Ravensbergen, adding that her findings may help explain this disconnect.

In her study, Ravensbergen assessed 20 people with spinal cord injury and 14 able-bodied controls to determine their risk for cardiovascular disease, including measurements for glucose tolerance, body mass index (BMI), body fat and abdominal fat. Those with SCI had decreased glucose tolerance and increased total and abdominal fat.

Ravensbergen then divided the SCI group into two subgroups: people with autonomic dysfunction and those without. While both groups had high cholesterol, she was surprised to find that those with autonomic dysfunction had problems with blood sugar. "These people are in a pre-diabetic state, which elevates their risk for heart disease," she says.

This study indicates that after the recovery period, there is value in screening the autonomic system to evaluate the cardiovascular system of spinal cord patients. Whether an increased risk of heart disease is truly due to the spinal cord injury or related to patient characteristics after such injury remains to be sorted out.

"This made-in-Canada research will aid people with spinal cord injury both in this country and across the globe," says Heart and Stroke Foundation spokesperson Dr. Beth Abramson. "It will be exciting to pursue this entirely new avenue, which will hopefully allow clinicians to streamline efforts to prevent heart disease in this group of patients."

People with spinal cord injury are normally tested for motor and sensory damage, but not for damage to the autonomic pathways, which run along the spinal cord, says Ravensbergen. "SCI in humans is never clear-cut. We never exactly know which pathways are affected. We don't really take into consideration how control of the cardiovascular system is affected," she explains.

Further studies are necessary to investigate the role that autonomic nerves play, how to better measure and improve autonomic function and, ultimately, the best ways to prevent heart disease, she adds.

Ravensbergen says this research could further help inform other autonomic dysfunction disorders and their relationship to heart health.


Story Source:

The above story is based on materials provided by Heart and Stroke Foundation of Canada. Note: Materials may be edited for content and length.


Cite This Page:

Heart and Stroke Foundation of Canada. "Spinal cord injuries associated with increased risk of heart disease, study finds." ScienceDaily. ScienceDaily, 24 October 2011. <www.sciencedaily.com/releases/2011/10/111024084628.htm>.
Heart and Stroke Foundation of Canada. (2011, October 24). Spinal cord injuries associated with increased risk of heart disease, study finds. ScienceDaily. Retrieved August 30, 2014 from www.sciencedaily.com/releases/2011/10/111024084628.htm
Heart and Stroke Foundation of Canada. "Spinal cord injuries associated with increased risk of heart disease, study finds." ScienceDaily. www.sciencedaily.com/releases/2011/10/111024084628.htm (accessed August 30, 2014).

Share This




More Health & Medicine News

Saturday, August 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

3 Things To Know About The Ebola Outbreak's Progression

3 Things To Know About The Ebola Outbreak's Progression

Newsy (Aug. 29, 2014) Here are three things you need to know about the deadly Ebola outbreak's progression this week. Video provided by Newsy
Powered by NewsLook.com
Killer Amoeba Found in Louisiana Water System

Killer Amoeba Found in Louisiana Water System

AP (Aug. 28, 2014) State health officials say testing has confirmed the presence of a killer amoeba in a water system serving three St. John the Baptist Parish towns. (Aug. 28) Video provided by AP
Powered by NewsLook.com
Who Could Be Burnt by WHO's E-Cigs Move?

Who Could Be Burnt by WHO's E-Cigs Move?

Reuters - Business Video Online (Aug. 28, 2014) The World Health Organisation has called for the regulation of electronic cigarettes as both tobacco and medical products. Ciara Lee looks at the impact of the move on the tobacco industry. Video provided by Reuters
Powered by NewsLook.com
CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

Newsy (Aug. 28, 2014) CDC director Tom Frieden says the Ebola outbreak is even worse than he feared. But he also said there's still hope to contain it. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins