Featured Research

from universities, journals, and other organizations

Older men with higher testosterone levels lose less muscle mass as they age

Date:
November 1, 2011
Source:
The Endocrine Society
Summary:
A recent study found that higher levels of testosterone were associated with reduced loss of lean muscle mass in older men, especially in those who were losing weight. In these men, higher testosterone levels were also associated with less loss of lower body strength.

A recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM) found that higher levels of testosterone were associated with reduced loss of lean muscle mass in older men, especially in those who were losing weight. In these men, higher testosterone levels were also associated with less loss of lower body strength.

Related Articles


Loss of muscle mass and strength contribute to frailty and are associated with falls, mobility limitations and fractures. Men lose more muscle mass and strength than women as they age, suggesting that sex steroids, and testosterone in particular, may contribute to body composition and physical function changes. This study sought to better understand the relationship between testosterone levels and healthy aging in older men and found that higher testosterone levels may help older men preserve muscle mass and delay frailty as they age.

"Our study finds that men, aged 65 years and older, with higher testosterone levels lost less muscle mass, especially in their arms and legs, than men this age who had lower testosterone levels," said Erin LeBlanc, MD, of Kaiser Permanente Northwest in Portland, OR and lead author of the study. "Men who had higher testosterone levels before they lost weight also lost less leg function and could stand up more easily from a chair than men who had lower testosterone levels before they lost weight."

In this study, researchers used data from 1,183 men aged 65 years or older and tested the hypothesis that higher baseline measures of sex steroids are associated with lesser declines in lean mass and maintenance of physical performance over an average follow-up of 4.5 years. Body composition was measured using dual energy x-ray absorptiometry (DXA) scans and physical performance was measured through a series of exercises that assessed grip strength, lower extremity power, walking speed and the ability to rise from a chair without the use of arms.

"The amount of testosterone men have in their bodies may contribute to how much muscle and strength they lose as they get older," said LeBlanc. "Our study adds evidence to the growing body of literature that suggest higher levels of endogenous testosterone may be favorably associated with some key components of healthy aging in men."

Other researchers working on the study include: Patty Wang, Christine Lee, Lynn Marshall and Eric Orwoll of Oregon Health & Science University in Portland; Elizabeth Barrett-Connor and Gail Laughlin of the University of California, San Diego in La Jolla, CA; Jane Cauley of the University of Pittsburgh in PA; and Andrew Hoffman of Stanford University in CA.


Story Source:

The above story is based on materials provided by The Endocrine Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. E. S. LeBlanc, P. Y. Wang, C. G. Lee, E. Barrett-Connor, J. A. Cauley, A. R. Hoffman, G. A. Laughlin, L. M. Marshall, E. S. Orwoll. Higher Testosterone Levels Are Associated with Less Loss of Lean Body Mass in Older Men. Journal of Clinical Endocrinology & Metabolism, 2011; DOI: 10.1210/jc.2011-0312

Cite This Page:

The Endocrine Society. "Older men with higher testosterone levels lose less muscle mass as they age." ScienceDaily. ScienceDaily, 1 November 2011. <www.sciencedaily.com/releases/2011/10/111027083043.htm>.
The Endocrine Society. (2011, November 1). Older men with higher testosterone levels lose less muscle mass as they age. ScienceDaily. Retrieved March 27, 2015 from www.sciencedaily.com/releases/2011/10/111027083043.htm
The Endocrine Society. "Older men with higher testosterone levels lose less muscle mass as they age." ScienceDaily. www.sciencedaily.com/releases/2011/10/111027083043.htm (accessed March 27, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, March 27, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

House Ready to Pass Medicare Doc Bill

House Ready to Pass Medicare Doc Bill

AP (Mar. 26, 2015) In rare bipartisan harmony, congressional leaders pushed a $214 billion bill permanently blocking physician Medicare cuts toward House passage Thursday, moving lawmakers closer to resolving a problem that has plagued them for years. (March 26) Video provided by AP
Powered by NewsLook.com
HIV Outbreak Prompts Public Health Emergency In Indiana

HIV Outbreak Prompts Public Health Emergency In Indiana

Newsy (Mar. 26, 2015) Indiana Gov. Mike Pence says he will bring additional state resources to help stop the epidemic. Video provided by Newsy
Powered by NewsLook.com
Indiana Permits Needle Exchange as HIV Cases Skyrocket

Indiana Permits Needle Exchange as HIV Cases Skyrocket

Reuters - US Online Video (Mar. 26, 2015) Governor Mike Pence declares the recent HIV outbreak in rural Indiana a "public health emergency" and authorizes a short-term needle-exchange program. Rough Cut (no reporter narration) Video provided by Reuters
Powered by NewsLook.com
AAA: Distracted Driving a Serious Teen Problem

AAA: Distracted Driving a Serious Teen Problem

AP (Mar. 25, 2015) While distracted driving is not a new problem for teens, new research from the AAA Foundation for Traffic Safety says it&apos;s much more serious than previously thought. (March 25) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins