Featured Research

from universities, journals, and other organizations

Microneedle sensors may allow real-time monitoring of body chemistry

Date:
December 14, 2011
Source:
North Carolina State University
Summary:
Researchers have developed new technology that uses microneedles to allow doctors to detect real-time chemical changes in the body -- and to continuously do so for an extended period of time.

Scanning electron micrograph of a hollow microneedle. In this study, hollow microneedles were integrated with sensors for detection of glucose, lactate, and pH levels.
Credit: Image courtesy of North Carolina State University

Researchers from North Carolina State University, Sandia National Laboratories, and the University of California, San Diego have developed new technology that uses microneedles to allow doctors to detect real-time chemical changes in the body -- and to continuously do so for an extended period of time.

"We've loaded the hollow channels within microneedles with electrochemical sensors that can be used to detect specific molecules or pH levels," says Dr. Roger Narayan, co-author of a paper describing the research, and a professor in the joint biomedical engineering department of NC State's College of Engineering and the University of North Carolina at Chapel Hill.

Existing technology relies on taking samples and testing them, whereas this approach allows continuous monitoring, Narayan explains. "For example, it could monitor glucose levels in a diabetic patient," Narayan says. Microneedles are very small needles in which at least one dimension -- such as length -- is less than one millimeter.

"The idea is that customized microneedle sensor arrays could be developed and incorporated into wearable devices, such as something like a wristwatch, to help answer specific medical or research questions," Narayan says. "It's also worth pointing out that microneedles are not painful."

In addition to its clinical applications, the new technology may also create opportunities for new research endeavors. For example, the microneedle sensor arrays could be used to track changes in lactate levels while people are exercising -- rather than measuring those levels only before and after exercise.

The researchers developed a proof-of-concept sensor array incorporating three types of sensors, which could measure pH, glucose and lactate. However, Narayan says the array could be modified to monitor a wide variety of chemicals.


Story Source:

The above story is based on materials provided by North Carolina State University. Note: Materials may be edited for content and length.


Journal Reference:

  1. Philip R. Miller, Shelby A. Skoog, Thayne L. Edwards, Deanna M. Lopez, David R. Wheeler, Dulce C. Arango, Xiaoyin Xiao, Susan M. Brozik, Joseph Wang, Ronen Polsky, Roger J. Narayan. Multiplexed microneedle-based biosensor array for characterization of metabolic acidosis. Talanta, 2011; DOI: 10.1016/j.talanta.2011.11.046

Cite This Page:

North Carolina State University. "Microneedle sensors may allow real-time monitoring of body chemistry." ScienceDaily. ScienceDaily, 14 December 2011. <www.sciencedaily.com/releases/2011/12/111213110243.htm>.
North Carolina State University. (2011, December 14). Microneedle sensors may allow real-time monitoring of body chemistry. ScienceDaily. Retrieved September 16, 2014 from www.sciencedaily.com/releases/2011/12/111213110243.htm
North Carolina State University. "Microneedle sensors may allow real-time monitoring of body chemistry." ScienceDaily. www.sciencedaily.com/releases/2011/12/111213110243.htm (accessed September 16, 2014).

Share This



More Matter & Energy News

Tuesday, September 16, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Manufacturer Prints 3-D Car In Record Time

Manufacturer Prints 3-D Car In Record Time

Newsy (Sep. 15, 2014) — Automobile manufacturer Local Motors created a drivable electric car using a 3-D printer. Printing the body only took 44 hours. Video provided by Newsy
Powered by NewsLook.com
Refurbished New York Subway Tunnel Unveiled After Sandy Damage

Refurbished New York Subway Tunnel Unveiled After Sandy Damage

Reuters - US Online Video (Sep. 15, 2014) — New York officials unveil subway tunnels that were refurbished after Superstorm Sandy. Nathan Frandino reports. Video provided by Reuters
Powered by NewsLook.com
Frustration As Drone Industry Outpaces Regulation In U.S.

Frustration As Drone Industry Outpaces Regulation In U.S.

Newsy (Sep. 14, 2014) — U.S. firms worry they’re falling behind in the marketplace as the FAA considers how to regulate commercial drones. Video provided by Newsy
Powered by NewsLook.com
Smart Gun Innovators Fear Backlash From Gun Rights Advocates

Smart Gun Innovators Fear Backlash From Gun Rights Advocates

Newsy (Sep. 14, 2014) — Winners of a contest for smart gun design are asking not to be named after others in the industry received threats for marketing similar products. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins