Featured Research

from universities, journals, and other organizations

Vitamin therapy can still reduce stroke, researchers contend

Date:
January 12, 2012
Source:
University of Western Ontario
Summary:
Medical researchers argue that vitamin therapy still has a role to play in reducing stroke.

A commentary by University of Western Ontario's David Spence and Harvard School of Public Health's Dr. Meir Stampfer in this week's Journal of the American Medical Association argues vitamin therapy still has a role to play in reducing stroke.

Related Articles


Vitamin B therapy was once widely used to lower homocysteine levels and too much of this amino acid in the bloodstream was linked to increased risk of stroke and heart attack. But several randomized trials found lowering homocysteine levels with B vitamins did not result in a cardiovascular benefit.

A study by Spence, a scientist with the Robarts Research Institute at Western's Schulich School of Medicine & Dentistry, found Vitamin B therapy actually increased cardiovascular risk in patients with diabetic nephropathy.

He says this commentary provides insights that overturn the widespread belief that homocysteine is dead. He says two key issues have been overlooked in the interpretation of several clinical trials: the key role of vitamin B12, and the newly recognized role of renal failure.

"It is now clear that the large trials showing no benefit of vitamin therapy obscured the benefit of vitamin therapy because they lumped together patients with renal failure and those with good renal function, says Spence, the author of How to Prevent Your Stroke. "The vitamins are harmful in renal failure, and beneficial in patients with good renal function, and they cancel each other out."

The commentary also contends most of the trials did not use a high enough dose of vitamin B12.


Story Source:

The above story is based on materials provided by University of Western Ontario. Note: Materials may be edited for content and length.


Journal Reference:

  1. J. D. Spence, M. J. Stampfer. Understanding the Complexity of Homocysteine Lowering With Vitamins: The Potential Role of Subgroup Analyses. JAMA: The Journal of the American Medical Association, 2011; 306 (23): 2610 DOI: 10.1001/jama.2011.1834

Cite This Page:

University of Western Ontario. "Vitamin therapy can still reduce stroke, researchers contend." ScienceDaily. ScienceDaily, 12 January 2012. <www.sciencedaily.com/releases/2011/12/111221140716.htm>.
University of Western Ontario. (2012, January 12). Vitamin therapy can still reduce stroke, researchers contend. ScienceDaily. Retrieved March 30, 2015 from www.sciencedaily.com/releases/2011/12/111221140716.htm
University of Western Ontario. "Vitamin therapy can still reduce stroke, researchers contend." ScienceDaily. www.sciencedaily.com/releases/2011/12/111221140716.htm (accessed March 30, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, March 30, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Soda, Salt and Sugar: The Next Generation of Taxes

Soda, Salt and Sugar: The Next Generation of Taxes

Washington Post (Mar. 30, 2015) — Denisa Livingston, a health advocate for the Dinι Community Advocacy Alliance, and the Post&apos;s Abby Phillip discuss efforts around the country to make unhealthy food choices hurt your wallet as much as your waistline. Video provided by Washington Post
Powered by NewsLook.com
UnitedHealth Buys Catamaran

UnitedHealth Buys Catamaran

Reuters - Business Video Online (Mar. 30, 2015) — The $12.8 billion merger will combine the U.S.&apos; third and fourth largest pharmacy benefit managers. Analysts say smaller PBMs could also merge. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
S. Leone in New Anti-Ebola Lockdown

S. Leone in New Anti-Ebola Lockdown

AFP (Mar. 28, 2015) — Sierra Leone imposed a three-day nationwide lockdown Friday for the second time in six months in a bid to prevent a resurgence of the deadly Ebola virus. Duration: 01:17 Video provided by AFP
Powered by NewsLook.com
These Popular Antibiotics Can Cause Permanent Nerve Damage

These Popular Antibiotics Can Cause Permanent Nerve Damage

Newsy (Mar. 27, 2015) — A popular class of antibiotic can leave patients in severe pain and even result in permanent nerve damage. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins