Featured Research

from universities, journals, and other organizations

Demographic and clinical factors appear associated with survival in patients with Parkinson disease

Date:
January 2, 2012
Source:
JAMA and Archives Journals
Summary:
Demographics and clinical factors appear to be associated with survival in patients with Parkinson disease (PD), and the presence of dementia is associated with a significant increase in mortality, according to a new report.

Demographics and clinical factors appear to be associated with survival in patients with Parkinson disease (PD), and the presence of dementia is associated with a significant increase in mortality, according to a report in the January issue of Archives of Neurology, one of the JAMA/Archives journals.

Although Parkinson disease is a common neurodegenerative disease among the elderly, there are conflicting data on the survival rates of patients with this disease, according to background information in the article.

Allison W. Willis, M.D., from Washington University School of Medicine, St. Louis, and colleagues conducted a nationwide retrospective cohort study of 138,000 Medicare beneficiaries with incident Parkinson disease who were identified in 2002 and followed up through 2008.

Sex and race "significantly predicted" survival, the researchers note. Patients who were women, Hispanic or Asian had a lower adjusted risk of death than white men. During the six-year study, 64 percent of patients with Parkinson disease died, with black patients having the highest crude death rate (66.4 percent), followed by white patients (64.6 percent), Hispanics (55.4 percent) and Asian patients (50.8 percent).

Dementia was diagnosed in 69.6 percent of the study population by the end of the study period and the highest frequency was found in black patients (78.2 percent) followed by Hispanics (73.1 percent). White and Asian patients with PD had lower, similar rates of dementia at 69 percent and 66.8 percent, respectively.

Patients with Parkinson disease and dementia had a greater likelihood of death than those without dementia. The researchers also note that patients with terminal Parkinson disease were hospitalized frequently for cardiovascular disease and infection but rarely for Parkinson disease. They also suggest Parkinson patients living in urban high industrial metal emission areas had a slightly higher adjusted risk of death, but researchers suggest more work is needed to understand if environmental exposures can influence the course of Parkinson disease or survival.

"We demonstrate that dementia occurs commonly in patients with incident PD 65 years and older; this had the strongest effect on age-adjusted survival among the variables that we studied," the authors conclude. "Our data highlight the need for prevention of or treatment for dementia in patients with PD because of its effect on survival," the authors conclude.


Story Source:

The above story is based on materials provided by JAMA and Archives Journals. Note: Materials may be edited for content and length.


Journal Reference:

  1. A. W. Willis, M. Schootman, N. Kung, B. A. Evanoff, J. S. Perlmutter, B. A. Racette. Predictors of Survival in Patients With Parkinson Disease. Archives of Neurology, 2012; DOI: 10.1001/archneurol.2011.2370

Cite This Page:

JAMA and Archives Journals. "Demographic and clinical factors appear associated with survival in patients with Parkinson disease." ScienceDaily. ScienceDaily, 2 January 2012. <www.sciencedaily.com/releases/2012/01/120102180848.htm>.
JAMA and Archives Journals. (2012, January 2). Demographic and clinical factors appear associated with survival in patients with Parkinson disease. ScienceDaily. Retrieved September 3, 2014 from www.sciencedaily.com/releases/2012/01/120102180848.htm
JAMA and Archives Journals. "Demographic and clinical factors appear associated with survival in patients with Parkinson disease." ScienceDaily. www.sciencedaily.com/releases/2012/01/120102180848.htm (accessed September 3, 2014).

Share This



More Health & Medicine News

Wednesday, September 3, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Snack Attack: Study Says Action Movies Make You Snack More

Snack Attack: Study Says Action Movies Make You Snack More

Newsy (Sep. 2, 2014) You're more likely to gain weight while watching action flicks than you are watching other types of programming, says a new study published in JAMA. Video provided by Newsy
Powered by NewsLook.com
U.N. Says Ebola Travel Restrictions Will Cause Food Shortage

U.N. Says Ebola Travel Restrictions Will Cause Food Shortage

Newsy (Sep. 2, 2014) The U.N. says the problem is two-fold — quarantine zones and travel restrictions are limiting the movement of both people and food. Video provided by Newsy
Powered by NewsLook.com
Doctors Fear They're Losing Battle Against Ebola

Doctors Fear They're Losing Battle Against Ebola

AP (Sep. 2, 2014) As a third American missionary is confirmed to have contracted Ebola in Liberia, doctors on the ground in West Africa fear they're losing the battle against the outbreak. (Sept. 2) Video provided by AP
Powered by NewsLook.com
Tech Giants Bet on 3D Headsets for Gaming, Healthcare

Tech Giants Bet on 3D Headsets for Gaming, Healthcare

AFP (Sep. 2, 2014) When Facebook acquired the virtual reality hardware developer Oculus VR in March for $2 billion, CEO Mark Zuckerberg hailed the firm's technology as "a new communication platform." Duration: 02:24 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins