Featured Research

from universities, journals, and other organizations

Two common sweeteners have different effects on the body, study suggests

Date:
January 23, 2012
Source:
University of Colorado Denver
Summary:
With growing concern that excessive levels of fructose may pose a great health risk -- causing high blood pressure, kidney disease and diabetes -- researchers set out to see if two common sweeteners in western diets differ in their effects on the body in the first few hours after ingestion. The study took a closer look at high-fructose corn syrup (HFCS) and table sugar (sucrose).

With growing concern that excessive levels of fructose may pose a great health risk -- causing high blood pressure, kidney disease and diabetes -- researchers at the University of Colorado School of Medicine, along with their colleagues at the University of Florida, set out to see if two common sweeteners in Western diets differ in their effects on the body in the first few hours after ingestion. The study, recently published in the journal Metabolism, took a closer look at high-fructose corn syrup (HFCS) and table sugar (sucrose) and was led by Dr. MyPhuong Le (now a postdoctoral fellow at the University of Colorado) and Dr. Julie Johnson, a professor of pharmacogenomics at the University of Florida.

Related Articles


Both HFCS and sucrose have historically been considered to have nearly identical effects on the body. But this study finds that indeed there is a difference between the two. They found that the makeup of the sugars resulted in differences in how much fructose was absorbed into the circulation, and which could have a potential impact on one's health. Sucrose is 50 percent fructose and 50 percent glucose that is bonded together as a disaccharide (complex carbohydrate), while HFCS is a mixture of free fructose (55 percent) and free glucose (45 percent). It's the difference in fructose amount that appears to create the ill health effects on the body.

Their study was conducted at the University of Florida, where they evaluated 40 men and women who were given 24 ounces of HFCS -- or sugar-sweetened soft drinks. Careful measurements showed that the HFCS-sweetened soft drinks resulted in significantly higher fructose levels than the sugar-sweetened drinks. Fructose is also known to increase uric acid levels that have been implicated in blood pressure, and the HFCS-sweetened drinks resulted in a higher uric acid level and a 3 mm Hg greater rise in systolic blood pressure.

Dr. Richard Johnson, a co-author in the study and chief of the Division of Renal Diseases and Hypertension at the University of Colorado, commented, "Although both sweeteners are often considered the same in terms of their biological effects, this study demonstrates that there are subtle differences. Soft drinks containing HFCS result in slightly higher blood levels of fructose than sucrose-sweetened drinks."

He added, "The next step is for new studies to address whether the long-term effects of these two sweeteners are different."


Story Source:

The above story is based on materials provided by University of Colorado Denver. Note: Materials may be edited for content and length.


Journal Reference:

  1. MyPhuong T. Le, Reginald F. Frye, Christopher J. Rivard, Jing Cheng, Kim K. McFann, Mark S. Segal, Richard J. Johnson, Julie A. Johnson. Effects of high-fructose corn syrup and sucrose on the pharmacokinetics of fructose and acute metabolic and hemodynamic responses in healthy subjects. Metabolism, 2011; DOI: 10.1016/j.metabol.2011.09.013

Cite This Page:

University of Colorado Denver. "Two common sweeteners have different effects on the body, study suggests." ScienceDaily. ScienceDaily, 23 January 2012. <www.sciencedaily.com/releases/2012/01/120123175707.htm>.
University of Colorado Denver. (2012, January 23). Two common sweeteners have different effects on the body, study suggests. ScienceDaily. Retrieved October 24, 2014 from www.sciencedaily.com/releases/2012/01/120123175707.htm
University of Colorado Denver. "Two common sweeteners have different effects on the body, study suggests." ScienceDaily. www.sciencedaily.com/releases/2012/01/120123175707.htm (accessed October 24, 2014).

Share This



More Plants & Animals News

Friday, October 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deep Sea 'mushroom' Could Be Early Branch on Tree of Life

Deep Sea 'mushroom' Could Be Early Branch on Tree of Life

Reuters - Innovations Video Online (Oct. 24, 2014) Miniature deep sea animals discovered off the Australian coast almost three decades ago are puzzling scientists, who say the organisms have proved impossible to categorise. Academics at the Natural History of Denmark have appealed to the world scientific community for help, saying that further information on Dendrogramma enigmatica and Dendrogramma discoides could answer key evolutionary questions. Jim Drury has more. Video provided by Reuters
Powered by NewsLook.com
Black Bear Cub Goes Sunday Shopping

Black Bear Cub Goes Sunday Shopping

Reuters - Light News Video Online (Oct. 23, 2014) Price check on honey? Bear cub startles Oregon drugstore shoppers. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Dances With Wolves in China's Wild West

Dances With Wolves in China's Wild West

AFP (Oct. 23, 2014) One man is on a mission to boost the population of wolves in China's violence-wracked far west. The animal - symbol of the Uighur minority there - is under threat with a massive human resettlement program in the region. Duration: 00:41 Video provided by AFP
Powered by NewsLook.com
Breakfast Debate: To Eat Or Not To Eat?

Breakfast Debate: To Eat Or Not To Eat?

Newsy (Oct. 23, 2014) Conflicting studies published in the same week re-ignited the debate over whether we should be eating breakfast. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins