Featured Research

from universities, journals, and other organizations

New catalyst promises cheaper, greener drugs

Date:
March 27, 2012
Source:
University of Toronto
Summary:
A chemistry team has discovered environmentally-friendly iron-based nanoparticle catalysts that work as well as the expensive, toxic, metal-based catalysts that are currently in wide use by the drug, fragrance and food industry.

A chemistry team at the University of Toronto has discovered environmentally-friendly iron-based nanoparticle catalysts that work as well as the expensive, toxic, metal-based catalysts that are currently in wide use by the drug, fragrance and food industry.

"It is always important to strive to make industrial syntheses more green, and using iron catalysts is not only much less toxic, but it is also much more cost effective," said Jessica Sonnenberg, a PhD student and lead author of a paper published this week in the Journal of the American Chemical Society.

The research, which was directed by Robert Morris, chair of the Department of Chemistry, involved several steps. Suspecting the existence of nanoparticles, the team first set out to identify the iron catalysts. They then conducted investigations using an electron microscope to confirm that the iron nanoparticles were actually being formed during catalysis. The next step was to ensure that the iron nanoparticles were the active catalytic agents. This was done with polymer and poisoning experiments which showed that only the iron atoms on the surface of a nanoparticle were active.

But a further challenge remained. "Catalysts, even cheap iron ones developed for these types of reaction, still suffer one major downfall," explained Sonnenberg. "They require a one-to-one ratio of very expensive organic ligands -- the molecule that binds to the central metal atom of a chemical compound -- to yield catalytic activity. Our discovery of functional surface nanoparticles opens the door to using much smaller ratios of these expensive compounds relative to the metal centres. This drastically reduces the overall cost of the transformations."

The research team included Neil Coombs at U of T's Centre for Nanostructure Imaging and Imagetek Analytical Imaging Inc., and Paul Dube of the Brockhouse Institute for Materials Research at McMaster University in Hamilton, Ontario. Funding was provided by the Natural Sciences and Engineering Research Council of Canada as a Discovery grant to Morris and as an Alexander Graham Bell Canada Graduate Scholarship and Vanier Scholarship to Sonnenberg.


Story Source:

The above story is based on materials provided by University of Toronto. Note: Materials may be edited for content and length.


Journal Reference:

  1. Jessica F. Sonnenberg, Neil Coombs, Paul A. Dube, Robert H. Morris. Iron Nanoparticles Catalyzing the Asymmetric Transfer Hydrogenation of Ketones. Journal of the American Chemical Society, 2012; 120326165122000 DOI: 10.1021/ja211658t

Cite This Page:

University of Toronto. "New catalyst promises cheaper, greener drugs." ScienceDaily. ScienceDaily, 27 March 2012. <www.sciencedaily.com/releases/2012/03/120327124350.htm>.
University of Toronto. (2012, March 27). New catalyst promises cheaper, greener drugs. ScienceDaily. Retrieved April 18, 2014 from www.sciencedaily.com/releases/2012/03/120327124350.htm
University of Toronto. "New catalyst promises cheaper, greener drugs." ScienceDaily. www.sciencedaily.com/releases/2012/03/120327124350.htm (accessed April 18, 2014).

Share This



More Matter & Energy News

Friday, April 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Small Reactors Could Be Future of Nuclear Energy

Small Reactors Could Be Future of Nuclear Energy

AP (Apr. 17, 2014) After the Fukushima nuclear disaster, the industry fell under intense scrutiny. Now, small underground nuclear power plants are being considered as the possible future of the nuclear energy. (April 17) Video provided by AP
Powered by NewsLook.com
Honda's New ASIMO Robot, More Human-Like Than Ever

Honda's New ASIMO Robot, More Human-Like Than Ever

AFP (Apr. 17, 2014) It walks and runs, even up and down stairs. It can open a bottle and serve a drink, and politely tries to shake hands with a stranger. Meet the latest ASIMO, Honda's humanoid robot. Duration: 00:54 Video provided by AFP
Powered by NewsLook.com
German Researchers Crack Samsung's Fingerprint Scanner

German Researchers Crack Samsung's Fingerprint Scanner

Newsy (Apr. 16, 2014) German researchers have used a fake fingerprint made from glue to bypass the fingerprint security system on Samsung's new Galaxy S5 smartphone. Video provided by Newsy
Powered by NewsLook.com
Porsche CEO Says Supercar Is Not Dead: Cue the Spyder 918

Porsche CEO Says Supercar Is Not Dead: Cue the Spyder 918

TheStreet (Apr. 16, 2014) The Porsche Spyder 918 proves that, in an automotive world obsessed with fuel efficiency, the supercar is not dead. Porsche North America CEO Detlev von Platen attributes the brand's consistent sales growth -- 21% in 2013 -- with an investment in new technology and expanded performance dynamics. The hybrid Spyder 918 has 887 horsepower and 944 lb-ft of torque, but it can run 18 miles on just an electric charge. The $845,000 vehicle is not a consumer-targeted vehicle but a brand statement. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins