Featured Research

from universities, journals, and other organizations

Dog-associated house dust protects against respiratory infection linked to asthma

Date:
June 19, 2012
Source:
American Society for Microbiology
Summary:
House dust from homes with dogs appears to protect against infection with a common respiratory virus that is associated with the development of asthma in children.

Boy and his dog. House dust from homes with dogs appears to protect against infection with a common respiratory virus that is associated with the development of asthma in children.
Credit: sonya etchison / Fotolia

House dust from homes with dogs appears to protect against infection with a common respiratory virus that is associated with the development of asthma in children.

Researchers from the University of California, San Francisco, recenlty presented their findings at the 2012 General Meeting of the American Society for Microbiology.

"In this study we found that feeding mice house dust from homes that have dogs present protected them against a childhood airway infectious agent, respiratory syncytial virus (RSV). RSV infection is common in infants and can manifest as mild to severe respiratory symptoms. Severe infection in infancy is associated with a higher risk of developing childhood asthma," says Kei Fujimura, a researcher on the study.

In the study Fujimura and her colleagues compared three groups of animals: Mice fed house dust from homes with dogs before being infected with RSV, mice infected with RSV without exposure to dust and a control group of mice not infected with RSV.

"Mice fed dust did not exhibit symptoms associated with RSV-mediated airway infection, such as inflammation and mucus production. They also possessed a distinct gastrointestinal bacterial composition compared to animals not fed dust," says Fujimura.

Pet ownership, in particular dogs, has previously been associated with protection against childhood asthma development, says Fujimura. Recently she and her colleagues demonstrated that the collection of bacterial communities (the microbiome) in house dust from homes that possess a cat or dog is compositionally distinct from house dust from homes with no pets.

"This led us to speculate that microbes within dog-associated house dust may colonize the gastrointestinal tract, modulate immune responses and protect the host against the asthmagenic pathogen RSV," says Fujimura. "This study represents the first step towards determining the identity of the microbial species which confer protection against this respiratory pathogen."

Identification of the specific species and mechanisms underlying this protective effect represents a crucial step towards understanding the critical role of microbes in defining allergic disease outcomes and could lead to development of microbial-based therapies to protect against RSV and ultimately reduce the risk of childhood asthma development, says Fujimura.


Story Source:

The above story is based on materials provided by American Society for Microbiology. Note: Materials may be edited for content and length.


Cite This Page:

American Society for Microbiology. "Dog-associated house dust protects against respiratory infection linked to asthma." ScienceDaily. ScienceDaily, 19 June 2012. <www.sciencedaily.com/releases/2012/06/120619225717.htm>.
American Society for Microbiology. (2012, June 19). Dog-associated house dust protects against respiratory infection linked to asthma. ScienceDaily. Retrieved September 20, 2014 from www.sciencedaily.com/releases/2012/06/120619225717.htm
American Society for Microbiology. "Dog-associated house dust protects against respiratory infection linked to asthma." ScienceDaily. www.sciencedaily.com/releases/2012/06/120619225717.htm (accessed September 20, 2014).

Share This



More Health & Medicine News

Saturday, September 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Sierra Leone's Nationwide Ebola Curfew Underway

Sierra Leone's Nationwide Ebola Curfew Underway

Newsy (Sep. 20, 2014) Sierra Leone is locked down as aid workers and volunteers look for new cases of Ebola. Video provided by Newsy
Powered by NewsLook.com
Changes Found In Brain After One Dose Of Antidepressants

Changes Found In Brain After One Dose Of Antidepressants

Newsy (Sep. 19, 2014) A study suggest antidepressants can kick in much sooner than previously thought. Video provided by Newsy
Powered by NewsLook.com
Could Grief Affect The Immune Systems Of Senior Citizens?

Could Grief Affect The Immune Systems Of Senior Citizens?

Newsy (Sep. 19, 2014) The study found elderly people are much more likely to become susceptible to infection than younger adults going though a similar situation. Video provided by Newsy
Powered by NewsLook.com
Jury Delivers Verdict in Salmonella Trial

Jury Delivers Verdict in Salmonella Trial

AP (Sep. 19, 2014) A federal jury has convicted three people in connection with an outbreak of salmonella poisoning five years ago that sickened hundreds of people and was linked to a number of deaths. (Sept. 19) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins