Featured Research

from universities, journals, and other organizations

Diet, exercise or both? What obese older adults need to do to reduce cardiometabolic risk

Date:
June 25, 2012
Source:
Endocrine Society
Summary:
Obese older adults can reduce their chance of developing the metabolic syndrome by losing weight through dieting alone, but adding exercise to a weight loss program has even more benefit, a new study finds. The results show that a combination of diet-induced weight loss and frequent exercise almost doubled the improvement in insulin sensitivity compared with dieting alone.

Obese older adults can reduce their chance of developing the metabolic syndrome by losing weight through dieting alone, but adding exercise to a weight loss program has even more benefit, a new study finds. The results, presented June 25 at The Endocrine Society's 94th Annual Meeting in Houston, show that a combination of diet-induced weight loss and frequent exercise almost doubled the improvement in insulin sensitivity compared with dieting alone.

Related Articles


The metabolic syndrome is a cluster of metabolic problems that raise the risk of Type 2 diabetes and heart disease: abdominal obesity as shown by a large waist circumference, disturbed lipids (low HDL or "good" cholesterol and high triglycerides), high blood pressure and high blood glucose (blood sugar). Although it is known that weight loss can reduce these risk factors, the most appropriate lifestyle treatment for obesity in older adults has been controversial, said the presenting author, Matthew Bouchonville, MD.

"It was not clear from prior studies in obese elderly adults whether the beneficial effects of diet and exercise are distinct from each other or have additive effects," said Bouchonville, an assistant professor at the University of Mexico Health Sciences Center and the New Mexico Veterans Affairs (VA) Health Care System in Albuquerque.

The researchers investigated the independent and combined effects of diet-induced weight loss and regular exercise in a one-year randomized controlled clinical trial, funded by the National Institute on Aging. They randomly assigned 107 obese adults ages 65 and older to one of four groups: weight management using a calorie-restricted diet, exercise (three times a week for 90 minutes each) without dieting, combined dieting with exercise, and controls (no diet or exercise).

The primary outcome analyzed was the degree of change in the insulin sensitivity index. Insulin sensitivity is the body's ability to successfully clear glucose from the bloodstream and is often impaired in obese people. This index was measured from the oral glucose tolerance test, a blood test for diabetes after the patient drinks a sugary drink.

Other measures obtained included those for the components of the metabolic syndrome as well as C-reactive protein, a measure of inflammation. Research has linked chronic inflammation to diabetes and heart disease.

Ninety-three participants completed the study. In the intention-to-treat analysis of all 107 subjects, the insulin sensitivity index did not improve in the exercise-alone group or the controls. This index did improve on average by 40 percent in the diet group and by 70 percent in the combined diet-exercise group after controlling for relevant covariates, Bouchonville reported.

"This suggests a distinct complementary effect of exercise on diet-induced weight loss," he said.

Weight loss by diet alone also led to improvements in blood pressure and C-reactive protein. Without weight loss, exercise did not result in improvement in these risk factors, Bouchonville said. Other measures that did not improve in the exercise-only group or the controls but did improve in the other two groups included glucose and insulin response to the oral glucose tolerance test (levels of insulin and glucose trended over several time points after the sugar intake), waist circumference, abdominal visceral (deep belly) fat, triglycerides and adiponectin. Adiponectin is a protein produced in fat cells that improves insulin sensitivity.


Story Source:

The above story is based on materials provided by Endocrine Society. Note: Materials may be edited for content and length.


Cite This Page:

Endocrine Society. "Diet, exercise or both? What obese older adults need to do to reduce cardiometabolic risk." ScienceDaily. ScienceDaily, 25 June 2012. <www.sciencedaily.com/releases/2012/06/120625100909.htm>.
Endocrine Society. (2012, June 25). Diet, exercise or both? What obese older adults need to do to reduce cardiometabolic risk. ScienceDaily. Retrieved November 23, 2014 from www.sciencedaily.com/releases/2012/06/120625100909.htm
Endocrine Society. "Diet, exercise or both? What obese older adults need to do to reduce cardiometabolic risk." ScienceDaily. www.sciencedaily.com/releases/2012/06/120625100909.htm (accessed November 23, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, November 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

WFP: Ebola Risks Heightened Among Women Throughout Africa

WFP: Ebola Risks Heightened Among Women Throughout Africa

AFP (Nov. 21, 2014) Having children has always been a frightening prospect in Sierra Leone, the world's most dangerous place to give birth, but Ebola has presented an alarming new threat for expectant mothers. Duration: 00:37 Video provided by AFP
Powered by NewsLook.com
Could Your Genes Be The Reason You're Single?

Could Your Genes Be The Reason You're Single?

Newsy (Nov. 21, 2014) Researchers in Beijing discovered a gene called 5-HTA1, and carriers are reportedly 20 percent more likely to be single. Video provided by Newsy
Powered by NewsLook.com
Raw: Paralyzed Marine Walks With Robotic Braces

Raw: Paralyzed Marine Walks With Robotic Braces

AP (Nov. 21, 2014) Marine Corps officials say a special operations officer left paralyzed by a sniper's bullet in Afghanistan walked using robotic leg braces in a ceremony to award him a Bronze Star. (Nov. 21) Video provided by AP
Powered by NewsLook.com
Milestone Birthdays Can Bring Existential Crisis, Study Says

Milestone Birthdays Can Bring Existential Crisis, Study Says

Newsy (Nov. 21, 2014) Researchers find that as people approach new decades in their lives they make bigger life decisions. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins