Featured Research

from universities, journals, and other organizations

How heat helps to treat cancer

Date:
August 8, 2012
Source:
Bangor University
Summary:
Researchers have identified a switch in cells that may help to kill tumors with heat. Prostate cancer and other localized tumors can be effectively treated by a combination of heat and an anti-cancer drug that damages the genes.

Research at Bangor University has identified a switch in cells that may help to kill tumors with heat. Prostate cancer and other localized tumors can be effectively treated by a combination of heat and an anti-cancer drug that damages the genes. Behind this novel therapy is the enigmatic ability of heat to switch off essential survival mechanisms in human cells. Although thermotherapy is now more widely used, the underlying principles are still unclear.

In a recent publication in the Journal of Cell Science researchers based in the School of Biological Sciences report now that heat modulates these survival systems by promoting the production of a novel protein. Intriguingly, this protein is only produced when elevated temperatures activate a gene that hides inside another gene.

The leader of the Genome Biology group, Dr Thomas Caspari says: “The discovery is reminiscent of a Russian doll were a set of smaller wooden figures is placed inside a larger doll. The existence of such hidden genes may explain why the human genome has a much smaller number of genes than initially expected. Our work may also help to improve heat-treatment of cancer for the benefit of patients. This research success was a real team effort made possible by the generous funding from Cancer Research Wales and the European Leonardo DaVinci Program.”


Story Source:

The above story is based on materials provided by Bangor University. Note: Materials may be edited for content and length.


Journal Reference:

  1. Simon Janes, Ulrike Schmidt, Karim Ashour Garrido, Nadja Ney, Susanna Concilio, Mohamed Zekri and Thomas Caspari. Heat induction of a novel Rad9 variant from a cryptic translation initiation site reduces mitotic commitment. Journal of Cell Science, 2012 DOI: 10.1242/%u200Bjcs.104075

Cite This Page:

Bangor University. "How heat helps to treat cancer." ScienceDaily. ScienceDaily, 8 August 2012. <www.sciencedaily.com/releases/2012/08/120808121810.htm>.
Bangor University. (2012, August 8). How heat helps to treat cancer. ScienceDaily. Retrieved August 27, 2014 from www.sciencedaily.com/releases/2012/08/120808121810.htm
Bangor University. "How heat helps to treat cancer." ScienceDaily. www.sciencedaily.com/releases/2012/08/120808121810.htm (accessed August 27, 2014).

Share This




More Health & Medicine News

Wednesday, August 27, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Predicting Heart Transplant Rejection With a Blood Test

Predicting Heart Transplant Rejection With a Blood Test

Ivanhoe (Aug. 27, 2014) Now a new approach to rejection of donor organs could change the way doctors predict transplant rejection…without expensive, invasive procedures. Video provided by Ivanhoe
Powered by NewsLook.com
Better Braces That Vibrate

Better Braces That Vibrate

Ivanhoe (Aug. 27, 2014) The length of time you have to keep your braces on could be cut in half thanks to a new device that speeds up the process. Video provided by Ivanhoe
Powered by NewsLook.com
Smartphone App Tracks Your Heart Rate

Smartphone App Tracks Your Heart Rate

Ivanhoe (Aug. 27, 2014) A new app that can track your heart rate 24/7 is available for download in your app store and its convenience could save your life. Video provided by Ivanhoe
Powered by NewsLook.com
Stroke in Young Adults

Stroke in Young Adults

Ivanhoe (Aug. 27, 2014) A stroke can happen at any time and affect anyone regardless of age. This mother chose to give her son independence and continue to live a normal life after he had a stroke at 18 years old. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins