Featured Research

from universities, journals, and other organizations

More pregnant women taking high blood pressure drugs, yet safety unclear

Date:
September 10, 2012
Source:
American Heart Association
Summary:
Nearly 5 percent of pregnant women are prescribed drugs to treat high blood pressure, including some drugs that aren’t considered safe for mothers or their babies, according to new research.

Nearly 5 percent of pregnant women are prescribed drugs to treat high blood pressure , including some drugs that aren't considered safe for mothers or their babies, according to new research in the American Heart Association's journal Hypertension.

Use of high blood pressure drugs during pregnancy is becoming increasingly common, said Brian T. Bateman, M.D., lead author and Assistant Professor of anesthesia at Harvard Medical School in Boston, Mass.

"While we know high blood pressure, or hypertension, occurs in about 6 percent to 8 percent of all pregnancies, we know little about how women and their doctors treat the condition," he said.

Researchers studied a database of more than 1 million Medicaid patients, of whom 48,453 (4.4 percent) filled prescriptions for high blood pressure drugs during their pregnancies.

They found:

  • Antihypertensive drug use increased from 3.5 percent to 4.9 percent between 2000 and 2006.
  • Antihypertensive drug users were older than non-users, more likely to have diabetes or kidney disease, and more likely to be Caucasian or African-American than Hispanic or Asian.
  • Nearly 2 percent of pregnant women filled prescriptions for these drugs during the first trimester; 1.7 percent during the second trimester; and 3.2 percent during the third trimester.
  • The drugs prescribed included ACE inhibitors and angiotensin receptor blockers -- both of which have been shown in studies to have harmful side effects during pregnancy.

Limited information is available about which antihypertensive drugs are safest and most effective for treating high blood pressure during pregnancy, Bateman said. In general, methyldopa and labetalol are the recommended antihypertensives for use during pregnancy. More research on which antihypertensives to prescribe during pregnancy and how to use them safely is urgently needed, he said.

"We know from reports that a number of harmful effects can occur from using ACE inhibitors or angiotensin receptor blockers, especially during the second and third trimester," Bateman said. "These drugs can cause poor growth, kidney problems and even death of the newborn. If women are taking one of these blood pressure medications and they become pregnant or plan to do so, they and their doctors should discuss treatment choices during pregnancy."

Co-authors are Sonia Hernandez-Diaz, M.D., Dr.P.H.; Krista F. Huybrechts, M.S., Ph.D.; Kristin Palmsten, M.S.; Helen Mogun, M.S.; Jeffrey L. Ecker, M.D. and Michael A. Fischer, M.D., M.S. Author disclosures are on the manuscript.


Story Source:

The above story is based on materials provided by American Heart Association. Note: Materials may be edited for content and length.


Journal Reference:

  1. Brian T. Bateman, Sonia Hernandez-Diaz, Krista F. Huybrechts, Kristin Palmsten, Helen Mogun, Jeffrey L. Ecker, and Michael A. Fischer. Patterns of Outpatient Antihypertensive Medication Use During Pregnancy in a Medicaid Population. Hypertension, 2012; DOI: 10.1161/HYPERTENSIONAHA.112.197095

Cite This Page:

American Heart Association. "More pregnant women taking high blood pressure drugs, yet safety unclear." ScienceDaily. ScienceDaily, 10 September 2012. <www.sciencedaily.com/releases/2012/09/120910161405.htm>.
American Heart Association. (2012, September 10). More pregnant women taking high blood pressure drugs, yet safety unclear. ScienceDaily. Retrieved September 2, 2014 from www.sciencedaily.com/releases/2012/09/120910161405.htm
American Heart Association. "More pregnant women taking high blood pressure drugs, yet safety unclear." ScienceDaily. www.sciencedaily.com/releases/2012/09/120910161405.htm (accessed September 2, 2014).

Share This




More Health & Medicine News

Tuesday, September 2, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Snack Attack: Study Says Action Movies Make You Snack More

Snack Attack: Study Says Action Movies Make You Snack More

Newsy (Sep. 2, 2014) You're more likely to gain weight while watching action flicks than you are watching other types of programming, says a new study published in JAMA. Video provided by Newsy
Powered by NewsLook.com
U.N. Says Ebola Travel Restrictions Will Cause Food Shortage

U.N. Says Ebola Travel Restrictions Will Cause Food Shortage

Newsy (Sep. 2, 2014) The U.N. says the problem is two-fold — quarantine zones and travel restrictions are limiting the movement of both people and food. Video provided by Newsy
Powered by NewsLook.com
Doctors Fear They're Losing Battle Against Ebola

Doctors Fear They're Losing Battle Against Ebola

AP (Sep. 2, 2014) As a third American missionary is confirmed to have contracted Ebola in Liberia, doctors on the ground in West Africa fear they're losing the battle against the outbreak. (Sept. 2) Video provided by AP
Powered by NewsLook.com
Tech Giants Bet on 3D Headsets for Gaming, Healthcare

Tech Giants Bet on 3D Headsets for Gaming, Healthcare

AFP (Sep. 2, 2014) When Facebook acquired the virtual reality hardware developer Oculus VR in March for $2 billion, CEO Mark Zuckerberg hailed the firm's technology as "a new communication platform." Duration: 02:24 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins