Featured Research

from universities, journals, and other organizations

Scientists bid to develop anthrax vaccine to counteract world bioterrorism threat

Date:
September 17, 2012
Source:
Cardiff University
Summary:
A team of scientists is leading new research to develop a vaccine against anthrax to help counteract the threat of bioterrorism.

A team of Cardiff University scientists is leading new research to develop a vaccine against anthrax to help counteract the threat of bioterrorism.

Working with scientists from the Republic of Georgia, Turkey and the USA, Professor Les Baillie from Cardiff University's School of Pharmacy and Pharmaceutical Sciences is leading a NATO project to tackle the potential misuse of anthrax.

"Currently the majority of the world's population is susceptible to infection with Bacillus anthracis the bacterium which causes anthrax," according to Professor Baillie, who leads the multi-national research collaboration.

"The US postal attacks in 2001 highlighted the vulnerability of civilian populations and brought home the need to develop effective, rapid, robust medical countermeasures to combat the threat posed by terrorist use of this organism," he added.

It is the growing concern over the threat posed by bioterrorism that has prompted world authorities like NATO through its Science for Peace and Security Programme to support efforts to develop more effective vaccines and medical countermeasures.

Efforts have so far been hampered by the fact that cases of naturally acquired human infection are rare in NATO countries. As a consequence, researchers have been forced to employ animal models to develop new vaccines.

The problem with this approach is the immune responses of animals and humans differ and as a consequence human clinical trials represent an essential element in confirming the efficacy of any new vaccine.

Such trials require access to several thousand volunteers at risk of infection and as such would be almost impossible to perform in Western Europe or the US.

In contrast anthrax represents a significant disease of animals and humans in the Cacuses and Central Asia. For this reason researchers from the UK and US have joined with colleagues from Turkey and the former Soviet republic of Georgia to tackle the problem.

Professor Baillie added: "These unique resources, combined with the expertise of NATO researchers offers us an unparalleled opportunity."

The outputs of this study are expected to underpin the development of future vaccines capable of conferring broad-spectrum, robust protection following minimal dosing.

Such vaccines would impact on two levels, locally they would directly improve the life of workers at risk of contracting anthrax such as farmers, and globally they would contribute to the protection of citizens from the use of anthrax as an agent of bio-terrorism.

An additional benefit of this work will be the establishment of a research centre in Georgia which will support infectious disease research and ultimately improve the lives of all of the people in the region.


Story Source:

The above story is based on materials provided by Cardiff University. Note: Materials may be edited for content and length.


Cite This Page:

Cardiff University. "Scientists bid to develop anthrax vaccine to counteract world bioterrorism threat." ScienceDaily. ScienceDaily, 17 September 2012. <www.sciencedaily.com/releases/2012/09/120917123420.htm>.
Cardiff University. (2012, September 17). Scientists bid to develop anthrax vaccine to counteract world bioterrorism threat. ScienceDaily. Retrieved July 29, 2014 from www.sciencedaily.com/releases/2012/09/120917123420.htm
Cardiff University. "Scientists bid to develop anthrax vaccine to counteract world bioterrorism threat." ScienceDaily. www.sciencedaily.com/releases/2012/09/120917123420.htm (accessed July 29, 2014).

Share This




More Health & Medicine News

Tuesday, July 29, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deadly Ebola Virus Threatens West Africa

Deadly Ebola Virus Threatens West Africa

AP (July 28, 2014) West African nations and international health organizations are working to contain the largest Ebola outbreak in history. It's one of the deadliest diseases known to man, but the CDC says it's unlikely to spread in the U.S. (July 28) Video provided by AP
Powered by NewsLook.com
$15B Deal on Vets' Health Care Reached

$15B Deal on Vets' Health Care Reached

AP (July 28, 2014) A bipartisan deal to improve veterans health care would authorize at least $15 billion in emergency spending to fix a veterans program scandalized by long patient wait times and falsified records. (July 28) Video provided by AP
Powered by NewsLook.com
Two Americans Contract Ebola in Liberia

Two Americans Contract Ebola in Liberia

Reuters - US Online Video (July 28, 2014) Two American aid workers in Liberia test positive for Ebola while working to combat the deadliest outbreak of the virus ever. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Traditional African Dishes Teach Healthy Eating

Traditional African Dishes Teach Healthy Eating

AP (July 28, 2014) Classes are being offered nationwide to encourage African Americans to learn about cooking fresh foods based on traditional African cuisine. The program is trying to combat obesity, heart disease and other ailments often linked to diet. (July 28) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins