Featured Research

from universities, journals, and other organizations

Children, young adults treated with radioactive iodine at elevated risk of developing secondary primary cancer

Date:
September 20, 2012
Source:
American Thyroid Association
Summary:
Children and young adult thyroid cancer patients who are treated with radioactive iodine have an elevated risk of developing a second primary malignancy, according to new data.

Children and young adult thyroid cancer patients who are treated with radioactive iodine have an elevated risk of developing a second primary malignancy, according to new data presented at the 82nd Annual Meeting of the American Thyroid Association in Québec City, Québec, Canada.

Related Articles


"The expected survival time for young patients with differentiated thyroid cancer is long. However, as new data elucidates, a need exists to judiciously weigh the benefits of radioactive iodine against the small, but real, increase in the risk of developing secondary primary malignancies," said Elizabeth Pearce, MD, of Boston Medical Center, and Program Co-Chair of the ATA Annual Meeting.

Though increasingly used as a treatment for differentiated thyroid cancer, long-term implication of radioactive iodine in children and young adults are not well defined. Existing data are limited to case series with limited follow-up that, in particular, may underestimate the risk of these patients developing secondary primary malignancies. To date, epidemiologic analyses of secondary primary malignancies risk have only been performed in the adult population.

A team of researchers led by Jennifer Marti, MD, of Beth Israel Medical Center in New York, thus sought to characterize of secondary primary malignancies among children. They analyzed 3,850 children and young adult patients (< 25 years old) with differentiated thyroid cancer who were followed in the NCI SEER cancer registry from 1973 to 2008. Among patients who were treated with radioactive iodine, researchers observed 26 cases of secondary primary malignancies, outnumbering the 18.3 cases researchers had expected. Researchers found that patients who were treated with radioactive iodine (40%) had a significantly elevated relative risk (SIR 1.42, p = .05) of developing a secondary primary malignancy at all sites; their risk of developing a salivary malignancy was especially elevated (SIR = 34.12, p < 0.001). Researchers also estimated that over a decade, ~1 in 227 children and young adults will develop a secondary primary malignancy attributed to radioactive iodine treatment and ~1 in 588 will develop a salivary cancer attributable to radioactive iodine treatment. Patients who were not treated with radioactive iodine did not have an elevated risk of developing a secondary primary malignancy.


Story Source:

The above story is based on materials provided by American Thyroid Association. Note: Materials may be edited for content and length.


Cite This Page:

American Thyroid Association. "Children, young adults treated with radioactive iodine at elevated risk of developing secondary primary cancer." ScienceDaily. ScienceDaily, 20 September 2012. <www.sciencedaily.com/releases/2012/09/120920153117.htm>.
American Thyroid Association. (2012, September 20). Children, young adults treated with radioactive iodine at elevated risk of developing secondary primary cancer. ScienceDaily. Retrieved October 31, 2014 from www.sciencedaily.com/releases/2012/09/120920153117.htm
American Thyroid Association. "Children, young adults treated with radioactive iodine at elevated risk of developing secondary primary cancer." ScienceDaily. www.sciencedaily.com/releases/2012/09/120920153117.htm (accessed October 31, 2014).

Share This



More Health & Medicine News

Friday, October 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

U.S. Ebola Response Measures Demonstrated

U.S. Ebola Response Measures Demonstrated

AP (Oct. 31, 2014) — Officials in the Washington area showed off Ebola response measures being taken at Dulles International Airport and the National Institutes of Health. (Oct. 31) Video provided by AP
Powered by NewsLook.com
Fauci Says Ebola Risk in US "essentially Zero"

Fauci Says Ebola Risk in US "essentially Zero"

AP (Oct. 30, 2014) — NIAID Director Anthony Fauci said the risk of Ebola becoming an epidemic in the U.S. is essentially zero Thursday at the Washington Ideas Forum. He also said an Ebola vaccine will be tested in West Africa in the next few months. (Oct. 30) Video provided by AP
Powered by NewsLook.com
Nurse Defies Ebola Quarantine With Bike Ride

Nurse Defies Ebola Quarantine With Bike Ride

AP (Oct. 30, 2014) — A nurse who vowed to defy Maine's voluntary quarantine for health care workers who treated Ebola patients followed through on her promise Thursday, leaving her home for an hour-long bike ride. (Oct. 30) Video provided by AP
Powered by NewsLook.com
Pot-Infused Edibles Raise Concerns in Colorado

Pot-Infused Edibles Raise Concerns in Colorado

AFP (Oct. 30, 2014) — Colorado may have legalized marijuana for recreational use, but the debate around the decision still continues, with a recent - failed - attempt to ban cannabis-infused edibles. Duration: 01:53 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins