Featured Research

from universities, journals, and other organizations

Ensuring high-quality dietary supplements with 'quality-by-design'

Date:
October 3, 2012
Source:
American Chemical Society
Summary:
If applied to the $5-billion-per-year dietary supplement industry, "quality by design" -- a mindset that helped revolutionize the manufacture of cars and hundreds of other products -- could ease concerns about the safety and integrity of the herbal products used by 80 percent of the world's population.

If applied to the $5-billion-per-year dietary supplement industry, "quality by design" (QbD) -- a mindset that helped revolutionize the manufacture of cars and hundreds of other products -- could ease concerns about the safety and integrity of the herbal products used by 80 percent of the world's population.

That's the conclusion of an article in ACS' Journal of Natural Products.

Ikhlas Khan and Troy Smillie explain that the U.S. Food and Drug Administration (FDA) regulates dietary supplements as a category of foods, rather than drugs. Manufacturers are responsible for the safety of their products. However, they need not obtain FDA approval to market supplements that contain ingredients generally regarded as safe. While manufacturers, packagers and distributors are required to follow good manufacturing practices, variations in growing, processing and even naming the plants used to make supplements opens the door to problems and introduces challenges with reproducibility. As a result, "the consumer must take it on faith that the supplement they are ingesting is an accurate representation of what is listed on the label, and that it contains the purportedly 'active' constituents they seek," Khan and Smillie note. The authors looked for solutions in a review of more than 100 studies on the topic.

They concluded that a QbD approach -- ensuring the quality of a product from its very inception -- is the best strategy. One key step in applying QbD to dietary supplements, for instance, would involve verifying the identities of the raw materials -- the plants -- used to make supplements. "It is clear that only a systematic designed approach can provide the required solution for complete botanical characterization, authentication and safety evaluation," they say.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Ikhlas A. Khan, Troy Smillie. Implementing a “Quality by Design” Approach to Assure the Safety and Integrity of Botanical Dietary Supplements. Journal of Natural Products, 2012; 75 (9): 1665 DOI: 10.1021/np300434j

Cite This Page:

American Chemical Society. "Ensuring high-quality dietary supplements with 'quality-by-design'." ScienceDaily. ScienceDaily, 3 October 2012. <www.sciencedaily.com/releases/2012/10/121003150904.htm>.
American Chemical Society. (2012, October 3). Ensuring high-quality dietary supplements with 'quality-by-design'. ScienceDaily. Retrieved October 20, 2014 from www.sciencedaily.com/releases/2012/10/121003150904.htm
American Chemical Society. "Ensuring high-quality dietary supplements with 'quality-by-design'." ScienceDaily. www.sciencedaily.com/releases/2012/10/121003150904.htm (accessed October 20, 2014).

Share This



More Health & Medicine News

Monday, October 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

How Nigeria Beat Its Ebola Outbreak

How Nigeria Beat Its Ebola Outbreak

Newsy (Oct. 20, 2014) The World Health Organization has declared Nigeria free of Ebola. Health experts credit a bit of luck and the government's initial response. Video provided by Newsy
Powered by NewsLook.com
Another Study Suggests Viagra Is Good For The Heart

Another Study Suggests Viagra Is Good For The Heart

Newsy (Oct. 20, 2014) An ingredient in erectile-dysfunction medications such as Viagra could improve heart function. Perhaps not surprising, given Viagra's history. Video provided by Newsy
Powered by NewsLook.com
Ebola Worries End for Dozens on U.S. Watch Lists

Ebola Worries End for Dozens on U.S. Watch Lists

Reuters - US Online Video (Oct. 20, 2014) Forty-three people who had contact with Thomas Eric Duncan, the first person diagnosed with Ebola in the U.S., were cleared overnight of twice-daily monitoring after 21 days of showing no symptoms. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Fauci: Ebola Protocols to Focus on Training

Fauci: Ebola Protocols to Focus on Training

AP (Oct. 20, 2014) Dr. Anthony Fauci, head of the National Institute of Allergy and Infectious Diseases, says he expects revised CDC protocols on Ebola to focus on training, observation and ensuring health care workers are more protected. (Oct. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins