Featured Research

from universities, journals, and other organizations

DNA findings hold potential for cancer treatment

Date:
October 8, 2012
Source:
Boise State University
Summary:
Six years ago, Boise State University biology professor Greg Hampikian and computer science colleague Tim Andersen announced that they had identified tiny DNA and protein sequences that were absent in nature. The researchers proposed that these sequences could have properties that were incompatible with life, and might serve as drugs to kill pathogens and even cancer. New research findings suggest this may be true.

Six years ago, Boise State University biology professor Greg Hampikian and computer science colleague Tim Andersen announced that they had identified tiny DNA and protein sequences that were absent in nature. Hampikian termed these sequences ‘nullomers’ and a headline in the New Scientist magazine proclaimed the sequences as “DNA Too Dangerous to Exist.”

The researchers proposed that these sequences could have properties that were incompatible with life, and might serve as drugs to kill pathogens and even cancer. New research findings suggest this may be true.

The October issue of the online journal Peptides will publish the first results of nullomer-based drugs. They show that these compounds kill breast and prostate cancer cells in the laboratory. More significantly, while their lethal effects on cancer cells increase over time, nullomer effects on normal cells decrease over time.

“We have a long way to go, but we finally have proof that nullomers have biological effects that can benefit human health,” Hampikian said.

Hampikian is known internationally for his work in DNA forensics, and he played a key role in the exoneration of Amanda Knox, the American college student convicted of the 2007 murder of her roommate in Perugia, Italy. In his Boise State lab, Hampikian and student and faculty collaborators work on diverse DNA projects, including developing new cancer drugs, discovering new species of single-celled organisms in Idaho, studying Basque sex chromosomes and inventing micro devices.


Story Source:

The above story is based on materials provided by Boise State University. Note: Materials may be edited for content and length.


Journal Reference:

  1. Abdelkrim Alileche, Jayita Goswami, William Bourland, Mike Davis, Greg Hampikian. Nullomer derived anticancer peptides (NulloPs): Differential lethal effects on normal and cancer cells in vitro. Peptides, 2012; DOI: 10.1016/j.peptides.2012.09.015

Cite This Page:

Boise State University. "DNA findings hold potential for cancer treatment." ScienceDaily. ScienceDaily, 8 October 2012. <www.sciencedaily.com/releases/2012/10/121008173331.htm>.
Boise State University. (2012, October 8). DNA findings hold potential for cancer treatment. ScienceDaily. Retrieved October 1, 2014 from www.sciencedaily.com/releases/2012/10/121008173331.htm
Boise State University. "DNA findings hold potential for cancer treatment." ScienceDaily. www.sciencedaily.com/releases/2012/10/121008173331.htm (accessed October 1, 2014).

Share This



More Health & Medicine News

Wednesday, October 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Pregnancy Spacing Could Have Big Impact On Autism Risks

Pregnancy Spacing Could Have Big Impact On Autism Risks

Newsy (Oct. 1, 2014) A new study says children born less than one year and more than five years after a sibling can have an increased risk for autism. Video provided by Newsy
Powered by NewsLook.com
Robotic Hair Restoration

Robotic Hair Restoration

Ivanhoe (Oct. 1, 2014) A new robotic procedure is changing the way we transplant hair. The ARTAS robot leaves no linear scarring and provides more natural results. Video provided by Ivanhoe
Powered by NewsLook.com
Insertable Cardiac Monitor

Insertable Cardiac Monitor

Ivanhoe (Oct. 1, 2014) A heart monitor the size of a paperclip that can save your life. The “Reveal Linq” allows a doctor to monitor patients with A-Fib on a continuous basis for up to 3 years! Video provided by Ivanhoe
Powered by NewsLook.com
Attacking Superbugs

Attacking Superbugs

Ivanhoe (Oct. 1, 2014) Two weapons hospitals can use to attack superbugs. Scientists in Ireland created a new gel resistant to superbugs, and a robot that can disinfect a room in minutes. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins