Featured Research

from universities, journals, and other organizations

Realizing the potential of stem cell therapy: Studies report progress in developing treatments for diseases and injuries

Date:
October 15, 2012
Source:
Society for Neuroscience (SfN)
Summary:
New animal studies provide additional support for investigating stem cell treatments for Parkinson's disease, head trauma, and dangerous heart problems that accompany spinal cord injury, according to research findings.

New animal studies provide additional support for investigating stem cell treatments for Parkinson's disease, head trauma, and dangerous heart problems that accompany spinal cord injury, according to research findings released today.

Related Articles


The work, presented at Neuroscience 2012, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health, shows scientists making progress toward using stem cell therapies to repair neurological damage.

The studies focused on using stem cells to produce neurons -- essential, message-carrying cells in the brain and spinal cord. The loss of neurons and the connections they make for controlling critical bodily functions are the chief hallmarks of brain and spinal cord injuries and of neurodegenerative afflictions such as Parkinson's disease and ALS (amyotrophic lateral sclerosis), also known as Lou Gehrig's disease.

Today's new findings show that:

  • Neurons derived from human embryonic stem cells implanted in monkeys displaying symptoms of Parkinson's disease appear to have matured into healthy, dopamine-producing neurons without causing any adverse effects (Dustin Wakeman, PhD, abstract 314.11).
  • Life-threatening heart problems caused by spinal cord injury were partially remedied in rats treated with stem cells derived from the fetal brainstem. The findings suggest new avenues of research for repairing cardiovascular damage in human patients with spinal cord injuries (Armin Blesch, PhD, abstract 637.10).
  • Experiments in mice indicate it may be possible to activate dormant stem cells in the adult prompting the production of new neurons that might help repair damage caused by injury (Nathaniel Hartman, PhD, abstract 823.07).

Other recent findings discussed show that:

  • Scientists believe they have isolated a protein that can signal the adult brain to produce more neurons, raising the possibility that boosting production of the protein could help patients recover neurons lost to degenerative diseases like Parkinson's and ALS, or to trauma, such as spinal cord injury (Anthony Conway, abstract 823.04).

"As the fields of developmental and regenerative neuroscience mature, important progress is being made to begin to translate the promise of stem cell therapy into meaningful treatments for a range of well-defined neurological problems," said press conference moderator Jeffrey Macklis, MD, of Harvard University and the Harvard Stem Cell Institute, an expert on development and regeneration of the mammalian central nervous system. "Solid, rigorous, and well-defined pre-clinical work in animals can set the stage toward human clinical trials and effective future therapies."


Story Source:

The above story is based on materials provided by Society for Neuroscience (SfN). Note: Materials may be edited for content and length.


Cite This Page:

Society for Neuroscience (SfN). "Realizing the potential of stem cell therapy: Studies report progress in developing treatments for diseases and injuries." ScienceDaily. ScienceDaily, 15 October 2012. <www.sciencedaily.com/releases/2012/10/121015171031.htm>.
Society for Neuroscience (SfN). (2012, October 15). Realizing the potential of stem cell therapy: Studies report progress in developing treatments for diseases and injuries. ScienceDaily. Retrieved November 24, 2014 from www.sciencedaily.com/releases/2012/10/121015171031.htm
Society for Neuroscience (SfN). "Realizing the potential of stem cell therapy: Studies report progress in developing treatments for diseases and injuries." ScienceDaily. www.sciencedaily.com/releases/2012/10/121015171031.htm (accessed November 24, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, November 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

AFP (Nov. 23, 2014) The arable district of Kenema in Sierra Leone -- at the centre of the Ebola outbreak in May -- has been under quarantine for three months as the cocoa harvest comes in. Duration: 01:32 Video provided by AFP
Powered by NewsLook.com
Don't Fall For Flu Shot Myths

Don't Fall For Flu Shot Myths

Newsy (Nov. 23, 2014) Misconceptions abound when it comes to your annual flu shot. Medical experts say most people older than 6 months should get the shot. Video provided by Newsy
Powered by NewsLook.com
WFP: Ebola Risks Heightened Among Women Throughout Africa

WFP: Ebola Risks Heightened Among Women Throughout Africa

AFP (Nov. 21, 2014) Having children has always been a frightening prospect in Sierra Leone, the world's most dangerous place to give birth, but Ebola has presented an alarming new threat for expectant mothers. Duration: 00:37 Video provided by AFP
Powered by NewsLook.com
Could Your Genes Be The Reason You're Single?

Could Your Genes Be The Reason You're Single?

Newsy (Nov. 21, 2014) Researchers in Beijing discovered a gene called 5-HTA1, and carriers are reportedly 20 percent more likely to be single. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins