Featured Research

from universities, journals, and other organizations

In vitro fertilization linked to increase risk for birth defects, research suggests

Date:
October 20, 2012
Source:
American Academy of Pediatrics
Summary:
In vitro fertilization may significantly increase the risk of birth defects, particularly those of the eye, heart, reproductive organs and urinary systems, according to new research.

In vitro fertilization (IVF) may significantly increase the risk of birth defects, particularly those of the eye, heart, reproductive organs and urinary systems, according to new research presented on Oct. 20, at the American Academy of Pediatrics (AAP) National Conference and Exhibition in New Orleans.

Related Articles


According to the study, despite increasing use of IVF in the United States, associations between birth defects and IVF are poorly understood. Management of birth defects comprises a large part of pediatric surgical care and demands significant health care resources.

According to the Centers for Disease Control, California has the highest rate of IVF usage in the United States. In the abstract, "Congenital Malformations Associated with Assisted Reproductive Technology: A California Statewide Analysis," researchers examined infants born in California from 2006-2007 after IVF and other treatments such as fertility-enhancing drugs or artificial insemination. Researchers examined maternal age, race, the number of times the mother had given birth, infant gender, year of birth and presence of major birth defects.

"Our findings included a significant association between the use of assisted reproductive technology, such as certain types of in vitro fertilization, and an increased risk of birth defects," said study author Lorraine Kelley-Quon, MD, a general surgery resident at Ronald Reagan UCLA Medical Center, who conducted the research at Mattel Children's Hospital UCLA.

Overall, 3,463 infants with major birth defects were identified among 4,795 infants born after IVF and 46,025 naturally conceived infants with similar maternal demographics. Birth defects were significantly increased for infants born after IVF -- 9 percent versus 6.6 percent for naturally conceived infants, even after controlling for maternal factors. Specifically, malformations of the eye (0.3 percent versus 0.2 percent), heart (5 percent versus 3 percent), and genitourinary system (1.5 percent versus 1 percent) were greater in IVF infants. Overall, an IVF infant's odds of birth defects were 1.25 times greater than that of a naturally conceived infant with similar maternal characteristics. Risk of birth defects after other fertility treatments such as artificial insemination or ovulation induction alone were not significant.

"For parents considering in vitro fertilization or other forms of assisted reproductive technology, it is important that they understand and discuss with their doctor the potential risks of the procedure before making a decision," said Kelley-Quon.


Story Source:

The above story is based on materials provided by American Academy of Pediatrics. Note: Materials may be edited for content and length.


Cite This Page:

American Academy of Pediatrics. "In vitro fertilization linked to increase risk for birth defects, research suggests." ScienceDaily. ScienceDaily, 20 October 2012. <www.sciencedaily.com/releases/2012/10/121020162613.htm>.
American Academy of Pediatrics. (2012, October 20). In vitro fertilization linked to increase risk for birth defects, research suggests. ScienceDaily. Retrieved March 31, 2015 from www.sciencedaily.com/releases/2012/10/121020162613.htm
American Academy of Pediatrics. "In vitro fertilization linked to increase risk for birth defects, research suggests." ScienceDaily. www.sciencedaily.com/releases/2012/10/121020162613.htm (accessed March 31, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Tuesday, March 31, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Soda, Salt and Sugar: The Next Generation of Taxes

Soda, Salt and Sugar: The Next Generation of Taxes

Washington Post (Mar. 30, 2015) — Denisa Livingston, a health advocate for the Dinι Community Advocacy Alliance, and the Post&apos;s Abby Phillip discuss efforts around the country to make unhealthy food choices hurt your wallet as much as your waistline. Video provided by Washington Post
Powered by NewsLook.com
UnitedHealth Buys Catamaran

UnitedHealth Buys Catamaran

Reuters - Business Video Online (Mar. 30, 2015) — The $12.8 billion merger will combine the U.S.&apos; third and fourth largest pharmacy benefit managers. Analysts say smaller PBMs could also merge. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
S. Leone in New Anti-Ebola Lockdown

S. Leone in New Anti-Ebola Lockdown

AFP (Mar. 28, 2015) — Sierra Leone imposed a three-day nationwide lockdown Friday for the second time in six months in a bid to prevent a resurgence of the deadly Ebola virus. Duration: 01:17 Video provided by AFP
Powered by NewsLook.com
These Popular Antibiotics Can Cause Permanent Nerve Damage

These Popular Antibiotics Can Cause Permanent Nerve Damage

Newsy (Mar. 27, 2015) — A popular class of antibiotic can leave patients in severe pain and even result in permanent nerve damage. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins