Featured Research

from universities, journals, and other organizations

Metals versus microbes: The biocidal effect of metalloacid-coated surfaces

Date:
November 14, 2012
Source:
BioMed Central Limited
Summary:
A new study reports of a phenomenon that could help control the spread of hospital-acquired infections: a surface-coating of metalloacids kills off microbial strains, even in multidrug-resistant microorganisms.

A new study published in BioMed Central's open access journal Antimicrobial Resistance and Infection Control reports of a phenomenon that could help control the spread of hospital-acquired infections: a surface-coating of metalloacids kills off microbial strains, even in multidrug-resistant microorganisms.

Related Articles


Hospital infections are a major public health concern, causing an estimated 99,000 deaths a year in the USA alone. Cleaning and disinfecting surfaces greatly helps reduce these infections. In addition, previous studies have indicated that metalloacids could limit the ability of microorganisms to survive by producing oxonium ions (H3O+), which creates an acidic pH.

In this novel study, the authors from the Centre Hospitalier Universitaire de Tours and the Centre Hospitalier Universitaire de Besanηon, France, set out to test the biocidal ability of molybdenum trioxide metalloacid-coated surfaces. To do this, they contaminated metalloacid-coated and non-coated surfaces by exposing them to microbial suspensions of eleven different microorganisms responsible for hospital infections.

The microorganisms tested were two Staphylococcus aureus strains, Clostridium difficile, three extended-spectrum beta-lactamase-producing Enterobacteriaceae strains, vancomycin-resistant vanA Enterococcus faecium, Psuedomonas aeruginosa, multidrug-resistant Acinetobacter baumanii, and two fungal strains of Candida albicans and Aspergillus fumigatus.

The authors found that the metalloacid-coated surfaces exhibited significant antimicrobial activity in all non-spore-forming organisms tested within 2-6 hours of initial contact. The coated surfaces greatly limited the survival of microorganisms, whereas microorganism numbers remained substantial on non-coated surfaces. Interestingly, spore-forming organisms were completely unaffected by the coated surfaces.

The biocidal reaction is thought to be caused by the diffusion H3O+ ions through microbial cell membranes, resulting in altered enzyme transport systems and inhibited metabolic activity.

Lead author Nathalie van der Mee-Marquet thinks that the findings of this study could greatly aid hospitals in controlling infection. She said, "In contrast to disinfectants and antibiotics, microbial resistance to metalloacids may not emerge, and they should be safe for human use. A molybdenum trioxide coating may be an effective and permanent means of minimizing microbial contamination between hospital cleaning procedures, particularly against multidrug-resistant organisms."

van der Mee-Marquet suggests that further studies should evaluate the benefits of the coating on medical devices and gauge whether it can be used as a complementary measure in hospitals for preventing the spread of nosocomial infections.


Story Source:

The above story is based on materials provided by BioMed Central Limited. Note: Materials may be edited for content and length.


Journal Reference:

  1. Nathalie Tιtault, Houssein Gbaguidi-Haore, Xavier Bertrand, Roland Quentin, Nathalie van der Mee-Marquet. Biocidal activity of metalloacid-coated surfaces against multidrug-resistant microorganisms. Antimicrobial Resistance and Infection Control, 2012; 1 (1): 35 DOI: 10.1186/2047-2994-1-35

Cite This Page:

BioMed Central Limited. "Metals versus microbes: The biocidal effect of metalloacid-coated surfaces." ScienceDaily. ScienceDaily, 14 November 2012. <www.sciencedaily.com/releases/2012/11/121113214639.htm>.
BioMed Central Limited. (2012, November 14). Metals versus microbes: The biocidal effect of metalloacid-coated surfaces. ScienceDaily. Retrieved December 20, 2014 from www.sciencedaily.com/releases/2012/11/121113214639.htm
BioMed Central Limited. "Metals versus microbes: The biocidal effect of metalloacid-coated surfaces." ScienceDaily. www.sciencedaily.com/releases/2012/11/121113214639.htm (accessed December 20, 2014).

Share This


More From ScienceDaily



More Plants & Animals News

Saturday, December 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) — In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
Monarch Butterflies Descend Upon Mexican Forest During Annual Migration

Monarch Butterflies Descend Upon Mexican Forest During Annual Migration

Reuters - Light News Video Online (Dec. 19, 2014) — Millions of monarch butterflies begin to descend onto Mexico as part of their annual migration south. Rough Cut (no reporter narration) Video provided by Reuters
Powered by NewsLook.com
Birds Might Be Better Meteorologists Than Us

Birds Might Be Better Meteorologists Than Us

Newsy (Dec. 19, 2014) — A new study suggests a certain type of bird was able to sense a tornado outbreak that moved through the U.S. a day before it hit. Video provided by Newsy
Powered by NewsLook.com
Navy Unveils Robot Fish

Navy Unveils Robot Fish

Reuters - Light News Video Online (Dec. 18, 2014) — The U.S. Navy unveils an underwater device that mimics the movement of a fish. Tara Cleary reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins