Featured Research

from universities, journals, and other organizations

Breath test could possibly diagnose colorectal cancer

Date:
December 5, 2012
Source:
Wiley
Summary:
A new study has demonstrated for the first time that a simple breath analysis could be used for colorectal cancer screening.

A new study published in the British Journal of Surgery (BJS) has demonstrated for the first time that a simple breath analysis could be used for colorectal cancer screening.

Related Articles


The study is part of the "Improving Outcomes in Gastrointestinal Cancer" supplement.

Cancer tissue has different metabolism compared to normal healthy cells and produces some substances which can be detected in the breath of these patients. Analysis of the volatile organic compounds (VOCs) linked to cancer is a new frontier in cancer screening.

Led by Donato F. Altomare, MD, of the Department of Emergency and Organ Transplantation at the University Aldo Moro of Bari, researchers collected exhaled breath from 37 patients with colorectal cancer and 41 healthy controls which was processed offline to evaluate the VOC profile. VOCs of interest had been identified and selected, and VOC patterns able to discriminate patients from controls set up.

A probabilistic neural network (PNN) was used to identify the pattern of VOCs that better discriminated between the two groups.

Results showed that patients with colorectal cancer have a different selective VOC pattern compared with healthy controls, based on analysis of 15 of 58 specific compounds in exhaled breath samples.

The PNN in this study was able to discriminate patients with colorectal cancer with an accuracy of over 75%, with the model correctly assigning 19 patients.

"The technique of breath sampling is very easy and non-invasive, although the method is still in the early phase of development," Altomare notes. "Our study's findings provide further support for the value of breath testing as a screening tool."


Story Source:

The above story is based on materials provided by Wiley. Note: Materials may be edited for content and length.


Journal Reference:

  1. D. F. Altomare, M. Di Lena, F. Porcelli, L. Trizio, E. Travaglio, M. Tutino, S. Dragonieri, V. Memeo, G. De Gennaro. Exhaled volatile organic compounds identify patients with colorectal cancer. British Journal of Surgery, 2012; DOI: 10.1002/bjs.8942

Cite This Page:

Wiley. "Breath test could possibly diagnose colorectal cancer." ScienceDaily. ScienceDaily, 5 December 2012. <www.sciencedaily.com/releases/2012/12/121205084323.htm>.
Wiley. (2012, December 5). Breath test could possibly diagnose colorectal cancer. ScienceDaily. Retrieved November 22, 2014 from www.sciencedaily.com/releases/2012/12/121205084323.htm
Wiley. "Breath test could possibly diagnose colorectal cancer." ScienceDaily. www.sciencedaily.com/releases/2012/12/121205084323.htm (accessed November 22, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, November 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

WFP: Ebola Risks Heightened Among Women Throughout Africa

WFP: Ebola Risks Heightened Among Women Throughout Africa

AFP (Nov. 21, 2014) Having children has always been a frightening prospect in Sierra Leone, the world's most dangerous place to give birth, but Ebola has presented an alarming new threat for expectant mothers. Duration: 00:37 Video provided by AFP
Powered by NewsLook.com
Could Your Genes Be The Reason You're Single?

Could Your Genes Be The Reason You're Single?

Newsy (Nov. 21, 2014) Researchers in Beijing discovered a gene called 5-HTA1, and carriers are reportedly 20 percent more likely to be single. Video provided by Newsy
Powered by NewsLook.com
Raw: Paralyzed Marine Walks With Robotic Braces

Raw: Paralyzed Marine Walks With Robotic Braces

AP (Nov. 21, 2014) Marine Corps officials say a special operations officer left paralyzed by a sniper's bullet in Afghanistan walked using robotic leg braces in a ceremony to award him a Bronze Star. (Nov. 21) Video provided by AP
Powered by NewsLook.com
Milestone Birthdays Can Bring Existential Crisis, Study Says

Milestone Birthdays Can Bring Existential Crisis, Study Says

Newsy (Nov. 21, 2014) Researchers find that as people approach new decades in their lives they make bigger life decisions. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins