Featured Research

from universities, journals, and other organizations

Scientists scan the human heart to create digital anatomical library

Date:
April 18, 2013
Source:
Journal of Visualized Experiments
Summary:
Medical researchers have demonstrated the anatomical reconstruction of an active human heart. The research uses contrast-computed tomography (CT) to allow in-depth 3-D computer modeling of hearts that can be used for prolonged archiving.

On April 18th JoVE (Journal of Visualized Experiments) will publish a new video article by Dr. Paul A Iaizzo demonstrating the anatomical reconstruction of an active human heart. The research uses contrast-computed tomography (CT) to allow in-depth 3-D computer modeling of hearts that can be used for prolonged archiving.

Computational technology, when combined with advanced imaging techniques like CT, gives researchers extensive insight to the structure and function of human organs. While often these techniques may be applied to modeling structural elements like a vertebrate's skeletal system, applying these imaging capabilities to cardiac tissue can create maps of an individual heart's venous system and musculature. In JoVE's new video article, surgeons and biomedical engineers from the University of Minnesota use these new technologies to create a digital library of human heart specimens.

Dr. Iaizzo's laboratory is able to collect human heart specimens from organ donors that were not deemed viable for transplant because the donor had been expired for too long, had a congenital heart defect, or the donor organ did not match a patient's immediate need. In these cases, Dr. Iaizzo and his colleagues around the world gain access to these organs for medical research and indexing. "We can look at a lot of the variations in heart anatomy [and] because everybody's heart is unique we can really understand variations and how the heart changes with disease."

By using contrast dyes and other reagents, Dr. Iaizzo can preserve and prepare the donated hearts to be in a diastolic state, the part of a heartbeat where the heart is filled with blood from the ventricles before expelling it into the aortas. This brings a deeper insight into physiological attributes of the heart, including fluid capacity and pressure on the heart chambers. Once the preserved hearts are scanned, computer models are generated, which allow approximations and correlations to be established between various heart shapes and disorders. Dr. Iaizzo expects this to assist in the design of cardiac devices.

"You don't have an appreciation for these specimens, and that you can still add contrast agents to them, without the video component," Dr. Iaizzo says of his decision to publish his methods in a video article, "The JoVE video shows how you can critically develop these [3-D models]. If someone is developing devices that can go into a cardiac venous or arterial system, then you can really look at these before and after treatments and see how the therapy actually worked."


Story Source:

The above story is based on materials provided by Journal of Visualized Experiments. Note: Materials may be edited for content and length.


Journal Reference:

  1. Julianne Spencer, Emily Fitch, Paul A. Iaizzo. Anatomical Reconstructions of the Human Cardiac Venous System using Contrast-computed Tomography of Perfusion-fixed Specimens. Journal of Visualized Experiments, 2013; (74) DOI: 10.3791/50258

Cite This Page:

Journal of Visualized Experiments. "Scientists scan the human heart to create digital anatomical library." ScienceDaily. ScienceDaily, 18 April 2013. <www.sciencedaily.com/releases/2013/04/130418104206.htm>.
Journal of Visualized Experiments. (2013, April 18). Scientists scan the human heart to create digital anatomical library. ScienceDaily. Retrieved July 30, 2014 from www.sciencedaily.com/releases/2013/04/130418104206.htm
Journal of Visualized Experiments. "Scientists scan the human heart to create digital anatomical library." ScienceDaily. www.sciencedaily.com/releases/2013/04/130418104206.htm (accessed July 30, 2014).

Share This




More Health & Medicine News

Wednesday, July 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
Concern Grows Over Worsening Ebola Crisis

Concern Grows Over Worsening Ebola Crisis

AFP (July 30, 2014) Pan-African airline ASKY has suspended all flights to and from the capitals of Liberia and Sierra Leone amid the worsening Ebola health crisis, which has so far caused 672 deaths in Guinea, Liberia and Sierra Leone. Duration: 00:43 Video provided by AFP
Powered by NewsLook.com
At Least 20 Chikungunya Cases in New Jersey

At Least 20 Chikungunya Cases in New Jersey

AP (July 30, 2014) At least 20 New Jersey residents have tested positive for chikungunya, a mosquito-borne virus that has spread through the Caribbean. (July 30) Video provided by AP
Powered by NewsLook.com
Generics Eat Into Pfizer's Sales

Generics Eat Into Pfizer's Sales

Reuters - Business Video Online (July 29, 2014) Pfizer, the world's largest drug maker, cut full-year revenue forecasts because generics could cut into sales of its anti-arthritis drug, Celebrex. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins