Featured Research

from universities, journals, and other organizations

Lab experiments question effectiveness of green coffee bean weight-loss supplements

Date:
June 12, 2013
Source:
American Chemical Society
Summary:
A major ingredient in those green coffee bean dietary supplements -- often touted as "miracle" weight-loss products -- doesn't prevent weight gain in obese laboratory mice fed a high-fat diet when given at higher doses. A new study also linked the ingredient to an unhealthy build-up of fat in the liver.

A major ingredient in those green coffee bean dietary supplements — often touted as “miracle” weight-loss products — doesn’t prevent weight gain in obese laboratory mice fed a high-fat diet when given at higher doses.
Credit: contrastwerkstatt / Fotolia

A major ingredient in those green coffee bean dietary supplements -- often touted as "miracle" weight-loss products -- doesn't prevent weight gain in obese laboratory mice fed a high-fat diet when given at higher doses. That's the conclusion of a first-of-its-kind study published in ACS' Journal of Agricultural and Food Chemistry. It also linked the ingredient to an unhealthy build-up of fat in the liver.

Vance Matthews, Kevin Croft and their team note that coffee is rich in healthful, natural, plant-based polyphenol substances. They cite evidence from past studies that coffee drinkers have a lower risk of obesity, high blood pressure, type 2 diabetes and other disorders collectively termed the "metabolic syndrome." Chlorogenic acid (CGA), one coffee polyphenol, is the main ingredient in scores of dietary supplements promoted as weight-loss products. Much research has been done on mixtures of coffee polyphenols. Until now, however, scientists have not checked the effects of higher doses of CGA alone on obesity and other symptoms of the metabolic syndrome. Matthews' team decided to do that, using special laboratory mice that are stand-ins for humans in such tests.

They report that mice on a high-fat diet and mice on a high-fat diet plus CGA gained the same amount of weight. The CGA mice, however, were more likely to develop disorders that often lead to type 2 diabetes. They also accumulated fat inside the cells in their livers. "This study suggests that higher doses of CGA supplementation in a high-fat diet does not protect against features of the metabolic syndrome in diet-induced obese mice," they say.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Aidilla Mubarak, Jonathan M. Hodgson, Michael J. Considine, Kevin D. Croft, Vance B. Matthews. Supplementation of a High-Fat Diet with Chlorogenic Acid Is Associated with Insulin Resistance and Hepatic Lipid Accumulation in Mice. Journal of Agricultural and Food Chemistry, 2013; 61 (18): 4371 DOI: 10.1021/jf400920x

Cite This Page:

American Chemical Society. "Lab experiments question effectiveness of green coffee bean weight-loss supplements." ScienceDaily. ScienceDaily, 12 June 2013. <www.sciencedaily.com/releases/2013/06/130612133149.htm>.
American Chemical Society. (2013, June 12). Lab experiments question effectiveness of green coffee bean weight-loss supplements. ScienceDaily. Retrieved October 20, 2014 from www.sciencedaily.com/releases/2013/06/130612133149.htm
American Chemical Society. "Lab experiments question effectiveness of green coffee bean weight-loss supplements." ScienceDaily. www.sciencedaily.com/releases/2013/06/130612133149.htm (accessed October 20, 2014).

Share This



More Health & Medicine News

Monday, October 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Microneedle Patch Promises Painless Pricks

Microneedle Patch Promises Painless Pricks

Reuters - Innovations Video Online (Oct. 18, 2014) Researchers at The National University of Singapore have invented a new microneedle patch that could offer a faster and less painful delivery of drugs such as insulin and painkillers. Video provided by Reuters
Powered by NewsLook.com
Raw: Nurse Nina Pham Arrives in Maryland

Raw: Nurse Nina Pham Arrives in Maryland

AP (Oct. 17, 2014) The first nurse to be diagnosed with Ebola at a Dallas hospital walked down the stairs of an executive jet into an ambulance at an airport in Frederick, Maryland, on Thursday. Pham will be treated at the National Institutes of Health. (Oct. 16) Video provided by AP
Powered by NewsLook.com
Raw: Cruise Ship Returns to US Over Ebola Fears

Raw: Cruise Ship Returns to US Over Ebola Fears

AP (Oct. 17, 2014) A Caribbean cruise ship carrying a Dallas health care worker who is being monitored for signs of the Ebola virus is heading back to Texas, US, after being refused permission to dock in Cozumel, Mexico. (Oct. 17) Video provided by AP
Powered by NewsLook.com
Spanish Govt: Four Suspected Ebola Cases in Spain Test Negative

Spanish Govt: Four Suspected Ebola Cases in Spain Test Negative

AFP (Oct. 17, 2014) All four suspected Ebola cases admitted to hospitals in Spain on Thursday have tested negative for the deadly virus in a first round of tests, the government said Friday. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins