Featured Research

from universities, journals, and other organizations

Scientists discover new mechanism regulating the immune response

Date:
June 28, 2013
Source:
Suomen Akatemia (Academy of Finland)
Summary:
Scientists in Finland have discovered a new mechanism regulating the immune response that can leave a person susceptible to autoimmune diseases.

Scientists at an Academy of Finland Centre of Excellence have discovered a new mechanism regulating the immune response that can leave a person susceptible to autoimmune diseases.

Related Articles


A fresh study by Turku Centre for Biotechnology and Aalto University in Finland is the first to report a new mechanism that regulates specification of lymphocytes, the white blood cells pivotal to immune response. By combining state-of-the art techniques, next-generation deep sequencing and computational data mining, the researchers discovered new epigenetic factors regulating lymphocyte function.

Regulatory regions of the genes studied displayed variations (single nucleotide polymorphisms or SNPs) that have been associated with predisposition to autoimmune diseases such as type1 diabetes, rheumatoid arthritis and inflammatory bowel disease. These discoveries provide new insight into and basis for the study of emergent mechanisms of immune-mediated diseases.

Immune-mediated diseases such as type 1 diabetes, rheumatoid arthritis, asthma and allergies result from abnormal immune response. T lymphocytes that orchestrate the immune response can differentiate into functionally distinct lineages to combat infection and disease. The correct response to cytokines and a controlled balance of T lymphocyte populations are critical for the immune system and for the avoidance of autoimmune disorders.


Story Source:

The above story is based on materials provided by Suomen Akatemia (Academy of Finland). Note: Materials may be edited for content and length.


Journal Reference:

  1. R. David Hawkins, Antti Larjo, Subhash K. Tripathi, Ulrich Wagner, Ying Luu, Tapio Lönnberg, Sunil K. Raghav, Leonard K. Lee, Riikka Lund, Bing Ren, Harri Lähdesmäki, Riitta Lahesmaa. Global Chromatin State Analysis Reveals Lineage-Specific Enhancers during the Initiation of Human T helper 1 and T helper 2 Cell Polarization. Immunity, 2013; 38 (6): 1271 DOI: 10.1016/j.immuni.2013.05.011

Cite This Page:

Suomen Akatemia (Academy of Finland). "Scientists discover new mechanism regulating the immune response." ScienceDaily. ScienceDaily, 28 June 2013. <www.sciencedaily.com/releases/2013/06/130628092117.htm>.
Suomen Akatemia (Academy of Finland). (2013, June 28). Scientists discover new mechanism regulating the immune response. ScienceDaily. Retrieved February 28, 2015 from www.sciencedaily.com/releases/2013/06/130628092117.htm
Suomen Akatemia (Academy of Finland). "Scientists discover new mechanism regulating the immune response." ScienceDaily. www.sciencedaily.com/releases/2013/06/130628092117.htm (accessed February 28, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, February 28, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Could a $34 Smartphone Device Improve HIV Diagnosis in Africa?

Could a $34 Smartphone Device Improve HIV Diagnosis in Africa?

Reuters - Innovations Video Online (Feb. 27, 2015) — A dongle that plugs into a Smartphone mimics a lab-based blood test for HIV and syphilis and can detect the diseases in 15 minutes, say researchers. Tara Cleary reports. Video provided by Reuters
Powered by NewsLook.com
Doctor Says Head Transplants Possible Within Two Years

Doctor Says Head Transplants Possible Within Two Years

Buzz60 (Feb. 27, 2015) — An Italian doctor is saying he could stick someone&apos;s head onto someone else&apos;s body. Patrick Jones (@Patrick_E_Jones) reports. Video provided by Buzz60
Powered by NewsLook.com
How Your Dentist Could Help Screen You For Diabetes

How Your Dentist Could Help Screen You For Diabetes

Newsy (Feb. 27, 2015) — A new study from researchers at New York University suggests dentists could soon use blood samples taken from patients&apos; mouths to test for diabetes. Video provided by Newsy
Powered by NewsLook.com
The Best Tips to Makeover Your Health

The Best Tips to Makeover Your Health

Buzz60 (Feb. 27, 2015) — If you&apos;re looking to boost your health this season, there are a few quick and easy steps to prompt you for success. Krystin Goodwin (@Krystingoodwin) has the best tips to give your health a makeover this spring! Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins