Featured Research

from universities, journals, and other organizations

Listening to blood cells: Simple test could use sound waves for diagnosing blood-related diseases

Date:
July 2, 2013
Source:
Cell Press
Summary:
New research reveals that when red blood cells are hit with laser light, they produce high frequency sound waves that contain a great deal of information. Similar to the way one can hear the voices of different people and identify who they are, investigators could analyze the sound waves produced by red blood cells and recognize their shape and size. The information may aid in the development of simple tests for blood-related diseases.

New research reveals that when red blood cells are hit with laser light, they produce high frequency sound waves that contain a great deal of information. Similar to the way one can hear the voices of different people and identify who they are, investigators reporting in the July 2 issue of Biophysical Journal, published by Cell Press, could analyze the sound waves produced by red blood cells and recognize their shape and size. The information may aid in the development of simple tests for blood-related diseases.
Credit: Strohm et al., Biophysical Journal

New research reveals that when red blood cells are hit with laser light, they produce high frequency sound waves that contain a great deal of information. Similar to the way one can hear the voices of different people and identify who they are, investigators reporting in the July 2 issue of Biophysical Journal, published by Cell Press, could analyze the sound waves produced by red blood cells and recognize their shape and size. The information may aid in the development of simple tests for blood-related diseases.

"We plan to make specialized devices that will allow the detection of individual red blood cells and analyze the photoacoustic signals they produce to rapidly diagnose red blood cell pathologies," says senior author Dr. Michael Kolios, of Ryerson University, Toronto.

Deviations from the regular biconcave shape of a red blood cell are a significant indicator of blood-related diseases, whether they result from genetic abnormalities, from infectious agents, or simply from a chemical imbalance. For example, malaria patients' red blood cells are irregularly swollen, while those of patients with sickle cell anemia take on a rigid, sickle shape.

Using a special photoacoustic microscope that detects sound, the investigators were able to differentiate healthy red blood cells from irregularly shaped red blood cells with high confidence, using a sample size of just 21 cells. Because each measurement takes only fractions of a second, the method could eventually be incorporated into an automated device for rapid characterization of red blood cells from a single drop of blood obtained in the clinic.

"We are currently developing a microfluidic device, which integrates the laser and probes and flows single cells through the target area. This would enable measuring thousands of cells in a very short period of time with minimal user involvement," says first author Eric Strohm, who is a graduate student in Dr. Kolios' laboratory. The investigators are applying the method to other types of cells as well, including white blood cells, and they are also using it to detect changes in photoacoustic signals that occur when blood cells clump together to form dangerous blood clots.


Story Source:

The above story is based on materials provided by Cell Press. Note: Materials may be edited for content and length.


Journal Reference:

  1. EricM. Strohm, Elizabeth S.L. Berndl, MichaelC. Kolios. Probing Red Blood Cell Morphology Using High-Frequency Photoacoustics. Biophysical Journal, 2013; 105 (1): 59 DOI: 10.1016/j.bpj.2013.05.037

Cite This Page:

Cell Press. "Listening to blood cells: Simple test could use sound waves for diagnosing blood-related diseases." ScienceDaily. ScienceDaily, 2 July 2013. <www.sciencedaily.com/releases/2013/07/130702123348.htm>.
Cell Press. (2013, July 2). Listening to blood cells: Simple test could use sound waves for diagnosing blood-related diseases. ScienceDaily. Retrieved July 28, 2014 from www.sciencedaily.com/releases/2013/07/130702123348.htm
Cell Press. "Listening to blood cells: Simple test could use sound waves for diagnosing blood-related diseases." ScienceDaily. www.sciencedaily.com/releases/2013/07/130702123348.htm (accessed July 28, 2014).

Share This




More Health & Medicine News

Monday, July 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

$15B Deal on Vets' Health Care Reached

$15B Deal on Vets' Health Care Reached

AP (July 28, 2014) A bipartisan deal to improve veterans health care would authorize at least $15 billion in emergency spending to fix a veterans program scandalized by long patient wait times and falsified records. (July 28) Video provided by AP
Powered by NewsLook.com
Traditional African Dishes Teach Healthy Eating

Traditional African Dishes Teach Healthy Eating

AP (July 28, 2014) Classes are being offered nationwide to encourage African Americans to learn about cooking fresh foods based on traditional African cuisine. The program is trying to combat obesity, heart disease and other ailments often linked to diet. (July 28) Video provided by AP
Powered by NewsLook.com
West Africa Gripped by Deadly Ebola Outbreak

West Africa Gripped by Deadly Ebola Outbreak

AFP (July 28, 2014) The worst-ever outbreak of the deadly Ebola epidemic grips west Africa, killing hundreds. Duration: 00:48 Video provided by AFP
Powered by NewsLook.com
Trees Could Save More Than 850 Lives Each Year

Trees Could Save More Than 850 Lives Each Year

Newsy (July 27, 2014) A national study conducted by the USDA Forest Service found that trees collectively save more than 850 lives on an annual basis. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins