Featured Research

from universities, journals, and other organizations

Cardiovascular risk in type 2 diabetics with dangerously low blood sugar levels

Date:
July 30, 2013
Source:
BMJ-British Medical Journal
Summary:
Type 2 diabetics who have severe hypoglycaemia are at higher risk of cardiovascular disease, a new article suggests.

Type 2 diabetics who have severe hypoglycaemia are at higher risk of cardiovascular disease, a new article suggests.

Severe hypoglycaemia is a condition where there is an abnormally low content of sugar in the blood. It is often classed as a medical emergency.

Severe hypoglycaemia is a potential risk factor for cardiovascular disease in patients with type 2 diabetes and recent clinical trials have failed to demonstrate a beneficial effect of intensive glucose control on overall CVD events.

Although observational studies have reported a positive association between severe hypoglycaemia and CVD risk, the association remains controversial. So researchers from Japan, the USA and the Netherlands carried out the first systematic review to assess this association.

They analysed the results of six studies involving a study population of 903,510 patients. Information on patients' characteristics was taken, including: age, gender, duration of diabetes, CVD history, insulin use, BMI and smoking status.

In total, 0.6 -- 5.8% of participants experienced severe hypoglycaemia from one to five years follow-up. Overall, this added just 1.56% to the total risk of developing cardiovascular disease in the whole population, but the link was consistent with all studies showing a positive correlation.

Given this risk, the researchers say avoiding severe hypoglycaemia may be important to prevent CVD and "less stringent glycaemic targets may be considered for type 2 diabetic patients at high risk of hypoglycaemia."

The positive association has been previously explained by having one or more other serious illnesses, but the researchers say this is unlikely to explain this. They suggest that the prevalence of serious illnesses would need to be "unrealistically high" among patients who experienced severe hypoglycaemia and the association between serious illnesses and cardiovascular disease would need to be "extremely strong."

In conclusion, the researchers say that their results suggest "that severe hypoglycaemia is associated with a 2-fold increased risk of CVD." They say that choices of glucose lowering agents with a low propensity to induce hypoglycaemia, patient education, and self-monitoring of blood glucose can be useful in preventing hypoglycaemia which in turn, "may be important to prevent cardiovascular disease in type 2 diabetes patients."


Story Source:

The above story is based on materials provided by BMJ-British Medical Journal. Note: Materials may be edited for content and length.


Journal Reference:

  1. A. Goto, O. A. Arah, M. Goto, Y. Terauchi, M. Noda. Severe hypoglycaemia and cardiovascular disease: systematic review and meta-analysis with bias analysis. BMJ, 2013; 347 (jul29 3): f4533 DOI: 10.1136/bmj.f4533

Cite This Page:

BMJ-British Medical Journal. "Cardiovascular risk in type 2 diabetics with dangerously low blood sugar levels." ScienceDaily. ScienceDaily, 30 July 2013. <www.sciencedaily.com/releases/2013/07/130730193526.htm>.
BMJ-British Medical Journal. (2013, July 30). Cardiovascular risk in type 2 diabetics with dangerously low blood sugar levels. ScienceDaily. Retrieved July 25, 2014 from www.sciencedaily.com/releases/2013/07/130730193526.htm
BMJ-British Medical Journal. "Cardiovascular risk in type 2 diabetics with dangerously low blood sugar levels." ScienceDaily. www.sciencedaily.com/releases/2013/07/130730193526.htm (accessed July 25, 2014).

Share This




More Health & Medicine News

Friday, July 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

AFP (July 24, 2014) A so-called drugs rehab 'clinic' is closed down in Pakistan after police find scores of ‘patients’ chained up alleging serial abuse. Duration 03:05 Video provided by AFP
Powered by NewsLook.com
Too Few Teens Receiving HPV Vaccination, CDC Says

Too Few Teens Receiving HPV Vaccination, CDC Says

Newsy (July 24, 2014) The Centers for Disease Control and Prevention is blaming doctors for the low number of children being vaccinated for HPV. Video provided by Newsy
Powered by NewsLook.com
New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Newsy (July 24, 2014) Sheik Umar Khan has treated many of the people infected in the Ebola outbreak, and now he's become one of them. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins