Featured Research

from universities, journals, and other organizations

Middle-aged men, women not equal in heart attack risk

Date:
August 16, 2013
Source:
Norwegian University of Science and Technology
Summary:
High cholesterol levels are much more risky for middle-aged men than middle-aged women when it comes to having a first heart attack, a new study of more than 40,000 Norwegian men and women has shown.

High cholesterol levels are much more risky for middle-aged men than middle-aged women when it comes to having a first heart attack, a new study of more than 40,000 Norwegian men and women has shown.

The study, just published in the September issue of Epidemiology, shows that being a middle-aged male and having high cholesterol levels results in a negative synergistic effect that the researchers did not observe in women. However, current clinical guidelines for treating high cholesterol levels do not differentiate between men and women.

"Our results suggest that in middle age, high cholesterol levels are much more detrimental for men than women, so that prevention efforts in this age group will have a greater potential to reduce the occurrence of a first heart attack in men," said Erik Madssen from the Norwegian University of Science and Technology's (NTNU) Department of Circulation and Medical Imaging, who was first author of the paper with Lars Erik Laugsand, also from NTNU.

The researchers used data from the Nord-Trøndelag Health Study, a county-wide survey carried out in 1995-1997 in Nord Trøndelag, Norway, that included blood sample collection from 65,000 people. Because the researchers hypothezised that female sex hormones could possibly protect women with respect to the prevalence of first heart attacks, they restricted their analysis to participants who were younger than 60 years old at the time of the survey.

In the end, the researchers had information from 23,525 women and 20,725 men who fit this category. During the nearly 12 years of follow-up on the participants who were younger than 60 years when the survey was conducted, there were 157 new cases of heart attacks in women and 553 in men.

They also conducted a secondary analysis of participants who were 60 years old or older at the time of the survey, which gave them another 20,138 individuals for the analysis. However, there was no evidence of a negative synergistic effect in male participants in this age group.

"Our findings suggest that middle-aged men with an unfortunate cholesterol profile have a significant additional risk of myocardial infarction than what previously has been thought," Madssen and Laugsand said. "Thus, these men should be treated more aggressively than what often is the case today, so that more infarctions can be prevented and lives can be saved."


Story Source:

The above story is based on materials provided by Norwegian University of Science and Technology. Note: Materials may be edited for content and length.


Journal Reference:

  1. Erik Madssen, Lars Erik Laugsand, Rune Wiseth, Bjørn Mørkedal, Carl Platou, Lars Vatten, Imre Janszky. Risk of Acute Myocardial Infarction. Epidemiology, 2013; 24 (5): 637 DOI: 10.1097/EDE.0b013e31829d2632

Cite This Page:

Norwegian University of Science and Technology. "Middle-aged men, women not equal in heart attack risk." ScienceDaily. ScienceDaily, 16 August 2013. <www.sciencedaily.com/releases/2013/08/130816094830.htm>.
Norwegian University of Science and Technology. (2013, August 16). Middle-aged men, women not equal in heart attack risk. ScienceDaily. Retrieved July 31, 2014 from www.sciencedaily.com/releases/2013/08/130816094830.htm
Norwegian University of Science and Technology. "Middle-aged men, women not equal in heart attack risk." ScienceDaily. www.sciencedaily.com/releases/2013/08/130816094830.htm (accessed July 31, 2014).

Share This




More Health & Medicine News

Thursday, July 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

House Republicans Vote to Sue Obama Over Healthcare Law

House Republicans Vote to Sue Obama Over Healthcare Law

Reuters - US Online Video (July 31, 2014) — The Republican-led House of Representatives votes to sue President Obama, accusing him of overstepping his executive authority in making changes to the Affordable Care Act. Mana Rabiee reports. Video provided by Reuters
Powered by NewsLook.com
Despite Health Questions, E-Cigs Are Beneficial: Study

Despite Health Questions, E-Cigs Are Beneficial: Study

Newsy (July 31, 2014) — Citing 81 previous studies, new research out of London suggests the benefits of smoking e-cigarettes instead of regular ones outweighs the risks. Video provided by Newsy
Powered by NewsLook.com
Dangerous Bacteria Kills One in Florida

Dangerous Bacteria Kills One in Florida

AP (July 31, 2014) — Sarasota County, Florida health officials have issued a warning against eating raw oysters and exposing open wounds to coastal and inland waters after a dangerous bacteria killed one person and made another sick. (July 31) Video provided by AP
Powered by NewsLook.com
Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) — Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



    Save/Print:
    Share:  

    Free Subscriptions


    Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

    Get Social & Mobile


    Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

    Have Feedback?


    Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
    Mobile iPhone Android Web
    Follow Facebook Twitter Google+
    Subscribe RSS Feeds Email Newsletters
    Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins