Featured Research

from universities, journals, and other organizations

Study identifies better blood glucose monitor for burn care

Date:
August 29, 2013
Source:
University of California - Davis Health System
Summary:
Glucose monitoring systems with an autocorrect feature that can detect red blood cells, vitamin C and other common interferents in burn patients' blood are better for monitoring care, a pilot study has found.

Glucose monitoring systems with an autocorrect feature that can detect red blood cells (hematocrit), vitamin C and other common interferents in burn patients' blood are better for monitoring care, a pilot study conducted by UC Davis researchers at the School of Medicine and College of Engineering has found. The study was published in the Journal of Burn Care Research.

Burn patients are at risk for high blood glucose levels, or hyperglycemia, due to the body's stress response. Intensive insulin therapy, which is commonly used to keep glucose under tight control, significantly reduces mortality and morbidity. But not all glucose monitoring systems are created equal, according to Nam Tran, assistant adjunct professor of pathology and laboratory medicine at UC Davis and lead author of the study.

"Many glucose monitoring systems, including those used throughout the five University of California health systems, may not adequately correct for interferents in the blood of burn patients," Tran said. "As a result, an inaccurate reading increases the potential for an insulin overdose. Our study showed that using a device that autocorrects for interferents can produce more accurate blood glucose measurements, which can improve insulin dosing and glucose control."

A multidisciplinary team of faculty and student researchers from the Department of Pathology and Laboratory Medicine, Department of Biomedical Engineering and the Department of Surgery conducted the study by assessing two different commercially available glucose monitoring systems in UC Davis' Firefighters Burn Institute Regional Burn Center.

Based on the researchers' findings, UC Davis patients at risk of hematocrit and vitamin C interferences, especially burn patients receiving high dose vitamin C therapy, will now be tested for glucose levels with the hospital's clinical chemistry laboratory analyzer. Tran is working with UC Davis clinical laboratory staff to install a flag notification in the electronic health record system to notify physicians about utilizing the hospital's laboratory analyzer for these high-risk patients.

Traditional hospital lab testing uses plasma (samples devoid of red blood cells), so it remains the most accurate method for measuring blood glucose levels. However, the newer autocorrecting devices use less blood, essentially one drop, and produce results in just five seconds, as opposed to approximately 10 to 20 minutes for lab testing.

"In a critical burn patient, glucose levels can change even within that small time frame," Tran said. "A glucose monitoring system that can autocorrect is a necessary requirement to improve the quality of patient care."

Future studies will evaluate the performance of the autocorrection features of newer glucose meters and assess whether autocorrection provides the most accurate glucose monitoring for all patient populations.

Tina L. Palmieri, professor of surgery and director of the Firefighters Burn Institute Regional Burn Center at UC Davis, is enthusiastic about the findings.

"Hyperglycemia is an important issue for burn patients because it decreases the body's ability to respond to infection and can cause other metabolic perturbations," Palmieri said. "Our published research has shown that administering insulin and controlling hyperglycemia decreases infection rates and improves outcomes in patients with severe burn injuries. However, controlling hyperglycemia can be problematic, as there are issues with monitor accuracy, calculation of the proper insulin dose and practitioner administration of insulin. This study addresses all three of these areas and may very well improve morbidity and mortality in burn patients."

Anthony G. Passerini, a UC Davis associate professor of biomedical engineering, launched the study with Tran. Passerini is the faculty instructor of the senior design course which pairs teams of undergraduate students with clinicians to identify needs and to design devices for improving health-care delivery.

"By bringing these technologies to the bedside, there is a real opportunity to improve patient care, by saving time and reducing human error," Passerini said.

Lydia P. Howell, professor and chair of pathology and laboratory medicine, believes this type of translational research has the potential to improve lives and transform health care.

"We strive to ensure that our patients have the most accurate and up-to-date testing methods available to them, and we are constantly working to improve the quality of care. I am especially pleased with the involvement of the undergraduate students in this study, as their contributions were significant and the experience they gained is excellent training for emerging leaders among the next generation of health-care providers."


Story Source:

The above story is based on materials provided by University of California - Davis Health System. Note: Materials may be edited for content and length.


Journal Reference:

  1. Nam K. Tran, Zachary R. Godwin, Jennifer C. Bockhold, Anthony G. Passerini, Julian Cheng, Morgan Ingemason. Clinical Impact of Sample Interference on Intensive Insulin Therapy in Severely Burned Patients. Journal of Burn Care & Research, 2013; 1 DOI: 10.1097/BCR.0b013e31829b3700

Cite This Page:

University of California - Davis Health System. "Study identifies better blood glucose monitor for burn care." ScienceDaily. ScienceDaily, 29 August 2013. <www.sciencedaily.com/releases/2013/08/130829145235.htm>.
University of California - Davis Health System. (2013, August 29). Study identifies better blood glucose monitor for burn care. ScienceDaily. Retrieved July 22, 2014 from www.sciencedaily.com/releases/2013/08/130829145235.htm
University of California - Davis Health System. "Study identifies better blood glucose monitor for burn care." ScienceDaily. www.sciencedaily.com/releases/2013/08/130829145235.htm (accessed July 22, 2014).

Share This




More Health & Medicine News

Tuesday, July 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com
$23.6 Billion Awarded To Widow In Smoking Lawsuit

$23.6 Billion Awarded To Widow In Smoking Lawsuit

Newsy (July 20, 2014) Cynthia Robinson claims R.J. Reynolds Tobacco Company hid the health and addiction risks of its products, leading to the death of her husband in 1996. Video provided by Newsy
Powered by NewsLook.com
Tooth Plaque Provides Insight Into Diets Of Ancient People

Tooth Plaque Provides Insight Into Diets Of Ancient People

Newsy (July 19, 2014) Research on plaque from ancient teeth shows that our prehistoric ancestor's had a detailed understanding of plants long before developing agriculture. Video provided by Newsy
Powered by NewsLook.com
Contaminated Water Kills 3 Babies in South African Town

Contaminated Water Kills 3 Babies in South African Town

AFP (July 18, 2014) Contaminated water in South Africa's northwestern town of Bloemhof kills three babies and hospitalises over 500 people. The incident highlights growing fears over water safety in South Africa. Duration: 02:22 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins