Featured Research

from universities, journals, and other organizations

Chemotherapy helps elderly patients with small cell lung cancer

Date:
September 4, 2013
Source:
International Association for the Study of Lung Cancer
Summary:
Researchers conclude that chemotherapy is associated with a greater than six-month improvement in median survival among elderly patients with small-cell lung cancer, even in patients over the age of 80 years.

Although numerous randomized clinical trials have demonstrated a benefit of chemotherapy for patients with small-cell lung cancer (SCLC), these trials have predominantly compared different chemotherapy regimens rather than comparing chemotherapy to best supportive care. Some of them included chest radiation or prophylactic cranial irradiation. Moreover, many trials excluded elderly patients.

Related Articles


A recent retrospective study looked at the benefit of chemotherapy on survival of elderly patients with SCLC in the community. This is the first large-scale analysis of chemotherapy use among patients with SCLC in the community setting.

In the October issue of the International Association for the Study of Lung Cancer's journal, the Journal of Thoracic Oncology (JTO), researchers conclude that chemotherapy is associated with a greater than 6-month improvement in median survival among elderly patients with SCLC, even in patients over the age of 80 years.

The researchers looked at data from 10,428 patients aged 65 years and older who were diagnosed with SCLC between 1992 and 2001. In this study, 67.1 percent received chemotherapy, most of whom (41.6 percent) received etoposide with carboplatin or cisplatin with or without other agents.

The researchers found that one third of elderly patients with SCLC never receive chemotherapy, and one sixth are never referred to a medical oncologist, suggesting that chemotherapy is underused.

They conclude that, "despite methodological limitations, their study provides strong evidence that chemotherapy improves survival in elderly patients with SCLC."

The lead author is Dr. Laura Caprario. Dr. Gary Strauss is a co-author and IASLC member.


Story Source:

The above story is based on materials provided by International Association for the Study of Lung Cancer. Note: Materials may be edited for content and length.


Cite This Page:

International Association for the Study of Lung Cancer. "Chemotherapy helps elderly patients with small cell lung cancer." ScienceDaily. ScienceDaily, 4 September 2013. <www.sciencedaily.com/releases/2013/09/130904161649.htm>.
International Association for the Study of Lung Cancer. (2013, September 4). Chemotherapy helps elderly patients with small cell lung cancer. ScienceDaily. Retrieved October 24, 2014 from www.sciencedaily.com/releases/2013/09/130904161649.htm
International Association for the Study of Lung Cancer. "Chemotherapy helps elderly patients with small cell lung cancer." ScienceDaily. www.sciencedaily.com/releases/2013/09/130904161649.htm (accessed October 24, 2014).

Share This



More Health & Medicine News

Friday, October 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com
WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com
Doctor in NYC Quarantined With Ebola

Doctor in NYC Quarantined With Ebola

AP (Oct. 24, 2014) An emergency room doctor who recently returned to the city after treating Ebola patients in West Africa has tested positive for the virus. He's quarantined in a hospital. (Oct. 24) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins