Featured Research

from universities, journals, and other organizations

Chemotherapy helps elderly patients with small cell lung cancer

Date:
September 4, 2013
Source:
International Association for the Study of Lung Cancer
Summary:
Researchers conclude that chemotherapy is associated with a greater than six-month improvement in median survival among elderly patients with small-cell lung cancer, even in patients over the age of 80 years.

Although numerous randomized clinical trials have demonstrated a benefit of chemotherapy for patients with small-cell lung cancer (SCLC), these trials have predominantly compared different chemotherapy regimens rather than comparing chemotherapy to best supportive care. Some of them included chest radiation or prophylactic cranial irradiation. Moreover, many trials excluded elderly patients.

A recent retrospective study looked at the benefit of chemotherapy on survival of elderly patients with SCLC in the community. This is the first large-scale analysis of chemotherapy use among patients with SCLC in the community setting.

In the October issue of the International Association for the Study of Lung Cancer's journal, the Journal of Thoracic Oncology (JTO), researchers conclude that chemotherapy is associated with a greater than 6-month improvement in median survival among elderly patients with SCLC, even in patients over the age of 80 years.

The researchers looked at data from 10,428 patients aged 65 years and older who were diagnosed with SCLC between 1992 and 2001. In this study, 67.1 percent received chemotherapy, most of whom (41.6 percent) received etoposide with carboplatin or cisplatin with or without other agents.

The researchers found that one third of elderly patients with SCLC never receive chemotherapy, and one sixth are never referred to a medical oncologist, suggesting that chemotherapy is underused.

They conclude that, "despite methodological limitations, their study provides strong evidence that chemotherapy improves survival in elderly patients with SCLC."

The lead author is Dr. Laura Caprario. Dr. Gary Strauss is a co-author and IASLC member.


Story Source:

The above story is based on materials provided by International Association for the Study of Lung Cancer. Note: Materials may be edited for content and length.


Cite This Page:

International Association for the Study of Lung Cancer. "Chemotherapy helps elderly patients with small cell lung cancer." ScienceDaily. ScienceDaily, 4 September 2013. <www.sciencedaily.com/releases/2013/09/130904161649.htm>.
International Association for the Study of Lung Cancer. (2013, September 4). Chemotherapy helps elderly patients with small cell lung cancer. ScienceDaily. Retrieved October 21, 2014 from www.sciencedaily.com/releases/2013/09/130904161649.htm
International Association for the Study of Lung Cancer. "Chemotherapy helps elderly patients with small cell lung cancer." ScienceDaily. www.sciencedaily.com/releases/2013/09/130904161649.htm (accessed October 21, 2014).

Share This



More Health & Medicine News

Tuesday, October 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

How Nigeria Beat Its Ebola Outbreak

How Nigeria Beat Its Ebola Outbreak

Newsy (Oct. 20, 2014) The World Health Organization has declared Nigeria free of Ebola. Health experts credit a bit of luck and the government's initial response. Video provided by Newsy
Powered by NewsLook.com
Another Study Suggests Viagra Is Good For The Heart

Another Study Suggests Viagra Is Good For The Heart

Newsy (Oct. 20, 2014) An ingredient in erectile-dysfunction medications such as Viagra could improve heart function. Perhaps not surprising, given Viagra's history. Video provided by Newsy
Powered by NewsLook.com
Ebola Worries End for Dozens on U.S. Watch Lists

Ebola Worries End for Dozens on U.S. Watch Lists

Reuters - US Online Video (Oct. 20, 2014) Forty-three people who had contact with Thomas Eric Duncan, the first person diagnosed with Ebola in the U.S., were cleared overnight of twice-daily monitoring after 21 days of showing no symptoms. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
CDC Calls for New Ebola Safety Guidelines

CDC Calls for New Ebola Safety Guidelines

AP (Oct. 20, 2014) Centers for Disease Control and Prevention Director Dr. Tom Frieden laid out new guidelines for health care workers when dealing with the deadly Ebola virus including new precautions when taking off personal protective equipment. (Oct. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins