Featured Research

from universities, journals, and other organizations

What works for women doesn't work for men

Date:
September 30, 2013
Source:
Wake Forest Baptist Medical Center
Summary:
Flushed face, sweating, a sudden rush of heat. The hot flash, the bane of menopausal women, also can affect men who are undergoing hormone therapy for prostate cancer.

Flushed face, sweating, a sudden rush of heat. The hot flash, the bane of menopausal women, also can affect men who are undergoing hormone therapy for prostate cancer.

Related Articles


But unlike in women, neither soy protein nor a common antidepressant provides relief for men, according to researchers at Wake Forest Baptist Medical Center.

Hot flashes occur in approximately 80 percent of men who are undergoing hormone manipulation as treatment for prostate cancer. Hormone therapy reduces the levels of male hormones, called androgens, to prevent them from reaching prostate cancer cells and stimulating their growth.

"Changing hormone levels cause hot flashes in both women and men, so we hoped that using soy supplements and/or an antidepressant would help reduce them in men as it does in many women," said Mara Vitolins, Dr. P.H., professor of public health sciences at Wake Forest Baptist and lead author of the study, which is published in the Sept. 30 online issue of the Journal of Clinical Oncology.

Participants in this Phase III, double-blind, multicenter study completed a seven day pre-screening phase and 12 weeks of intervention. One hundred and twenty men, ages 46 to 91, who were androgen-deprived were randomly assigned to one of four daily regimens: placebo pill and milk powder; venlafaxine, an antidepressant commonly prescribed to treat hot flashes in women, and milk powder protein; soy protein powder and placebo pill; or venlafaxine and milk powder.

Hot flash symptom severity and frequency and quality of life were assessed by the researchers.

The researchers found that neither venlafaxine nor soy protein alone or in combination reduced hot flashes in men.

"Utilizing interventions that appear effective in decreasing hot flashes in women to treat men who have hot flashes has proven to be relatively ineffective," Vitolins said. These findings highlight the need for continuing efforts to identify treatments for hot flashes that are specifically developed for men, Vitolins said.


Story Source:

The above story is based on materials provided by Wake Forest Baptist Medical Center. Note: Materials may be edited for content and length.


Journal Reference:

  1. M. Z. Vitolins, L. Griffin, W. V. Tomlinson, J. Vuky, P. T. Adams, D. Moose, B. Frizzell, G. J. Lesser, M. Naughton, J. E. Radford, E. G. Shaw. Randomized Trial to Assess the Impact of Venlafaxine and Soy Protein on Hot Flashes and Quality of Life in Men With Prostate Cancer. Journal of Clinical Oncology, 2013; DOI: 10.1200/JCO.2012.48.1432

Cite This Page:

Wake Forest Baptist Medical Center. "What works for women doesn't work for men." ScienceDaily. ScienceDaily, 30 September 2013. <www.sciencedaily.com/releases/2013/09/130930161523.htm>.
Wake Forest Baptist Medical Center. (2013, September 30). What works for women doesn't work for men. ScienceDaily. Retrieved March 6, 2015 from www.sciencedaily.com/releases/2013/09/130930161523.htm
Wake Forest Baptist Medical Center. "What works for women doesn't work for men." ScienceDaily. www.sciencedaily.com/releases/2013/09/130930161523.htm (accessed March 6, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, March 6, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Bupa Eyes India Healthcare Opportunities

Bupa Eyes India Healthcare Opportunities

Reuters - Business Video Online (Mar. 5, 2015) Bupa is hoping to expand in India&apos;s fast-growing health insurance market, once a rule change on foreign investment is implemented. The British private healthcare group&apos;s CEO tells Grace Pascoe why it&apos;s so keen on the new opportunity. Video provided by Reuters
Powered by NewsLook.com
Liberia Releases Last Ebola Patient, But Threat Remains

Liberia Releases Last Ebola Patient, But Threat Remains

Newsy (Mar. 5, 2015) Liberia&apos;s last Ebola patient has been released, and the country hasn&apos;t recorded a new case in a week. However, fears of another outbreak still exist. Video provided by Newsy
Powered by NewsLook.com
Doctor in Your Pocket Is Getting Smarter

Doctor in Your Pocket Is Getting Smarter

Reuters - Business Video Online (Mar. 5, 2015) Mobile apps are turning smartphones into a personal doctors, with users able to measure heart rate, blood pressure and even blood sugar. But will it change our behaviour? Ivor Bennett reports from the Mobile World Congress in Barcelona. Video provided by Reuters
Powered by NewsLook.com
AbbVie Inks $21B Deal To Buy Cancer Drugmaker Pharmacyclics

AbbVie Inks $21B Deal To Buy Cancer Drugmaker Pharmacyclics

Newsy (Mar. 5, 2015) AbbVie announced Wednesday it will buy cancer drugmaker Pharmacyclics in a $21 billion deal. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins