Featured Research

from universities, journals, and other organizations

Improving the performance of titanium implants

Date:
October 3, 2013
Source:
National Institute for Materials Science
Summary:
Researchers in Japan and China tested a novel urease fabrication process for coating titanium implants with bioactive CaP/gelatin composites. The research suggests that titanium implants coated with CaP and gelatin have great potential in clinical joint replacement or dental implants.

Researchers in Japan and China tested a novel urease fabrication process for coating titanium implants with bioactive CaP/gelatin composites. Published in Science and Technology of Advanced Materials, the research suggests that titanium implants coated with CaP and gelatin have great potential in clinical joint replacement or dental implants.

Related Articles


Titanium (Ti) and its alloys are the most popular materials used in orthopedic implants because of their good mechanical and chemical properties, biocompatibility, corrosion resistance and low allergenicity. One drawback, however, is that they cannot bond directly to living bone, but need to be coated with bioactive materials to improve their integration.

Calcium phosphate (CaP) and collagen are the main constituents of natural bone, and therefore gelatin – a denatured form of collagen – has excellent biodegradability and biocompatibility properties. Many organic-inorganic composites combine the advantages of each component, hence a composite of CaP and gelatin may be an effective coating for Ti implants.

In a study published in the journal Science and Technology of Advanced Materials, researchers in Japan and China tested a novel urease fabrication process for coating titanium implants with bioactive CaP/gelatin composites.

In the study, Wei-Qi Yan and colleagues implanted tiny 2 mm by 10 mm CaP/gel/Ti and CaP/Ti rods into the thigh bone of rabbits, while pure Ti rods served as controls. Four and eight weeks following the operation, the authors observed much more new bone on the surface of the composite CaP/gel/Ti rods than in the other two groups. What's more, the CaP/gel/Ti rods bonded to the surrounding bone directly, with no intervening soft tissue layer.

The authors concluded that the CaP/gel/Ti implants fabricated using their urease process not only enhanced the proliferation of stem cells and differentiation of bone cells, but also the bone bonding ability of the implants. This research suggests that titanium implants coated with CaP and gelatin have great potential in clinical joint replacement or dental implants.


Story Source:

The above story is based on materials provided by National Institute for Materials Science. Note: Materials may be edited for content and length.


Journal Reference:

  1. Zhong-Ming Huang, Yi-Ying Qi, Shao-Hua Du, Gang Feng, Hidero Unuma, Wei-Qi Yan. Promotion of osteogenic differentiation of stem cells and increase of bone-bonding abilityin vivousing urease-treated titanium coated with calcium phosphate and gelatin. Science and Technology of Advanced Materials, 2013; 14 (5): 055001 DOI: 10.1088/1468-6996/14/5/055001

Cite This Page:

National Institute for Materials Science. "Improving the performance of titanium implants." ScienceDaily. ScienceDaily, 3 October 2013. <www.sciencedaily.com/releases/2013/10/131003142214.htm>.
National Institute for Materials Science. (2013, October 3). Improving the performance of titanium implants. ScienceDaily. Retrieved October 24, 2014 from www.sciencedaily.com/releases/2013/10/131003142214.htm
National Institute for Materials Science. "Improving the performance of titanium implants." ScienceDaily. www.sciencedaily.com/releases/2013/10/131003142214.htm (accessed October 24, 2014).

Share This



More Health & Medicine News

Friday, October 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com
WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com
Doctor in NYC Quarantined With Ebola

Doctor in NYC Quarantined With Ebola

AP (Oct. 24, 2014) An emergency room doctor who recently returned to the city after treating Ebola patients in West Africa has tested positive for the virus. He's quarantined in a hospital. (Oct. 24) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins