Featured Research

from universities, journals, and other organizations

No viral cause for breast cancer and brain tumors

Date:
October 8, 2013
Source:
University of Gothenburg
Summary:
A major study has now disproved theories of a viral cause for breast cancer and the brain tumour, glioblastoma. The study, which was based on over seven billion DNA sequences, found no genetic traces of viruses in these forms of cancer. It has been scientifically proven that about 15 per cent of all cancer cases are the result of viral infection, but many researchers believe that even more cancers could be caused by viruses.

A major study conducted at the Sahlgrenska Academy has now disproved theories of a viral cause for breast cancer and the brain tumour, glioblastoma. The study, which was based on over seven billion DNA sequences and which is published in Nature Communications, found no genetic traces of viruses in these forms of cancer.

Related Articles


It has been scientifically proven that about 15 per cent of all cancer cases are the result of viral infection, but many researchers believe that even more cancers could be caused by viruses. Among other theories, it is suggested that the Epstein-Barr virus could be a possible cause of breast cancer and that the cytomegalovirus might cause the malignant brain tumour glioblastoma.

Extremely comprehensive study "There is some controversy in that we have not found any viruses in these forms of cancer, but if there were any viral involvement in breast cancer and glioblastoma, it is likely that we would have found some trace of it. We have based our research on American material, which is extremely comprehensive," says Erik Larsson, who is a researcher at the Sahlgrenska Academy at the University of Gothenburg.

700 billion DNA sequences The study was published in the scientific journal Nature Communications. The study involved the researchers using powerful computers to conduct in-depth analysis of 700 billion DNA sequences from more than 4,000 tumours.

"We conducted an unbiased search for viruses in 19 different types of cancer. The analysis has neatly confirmed the links that are already known, which effectively confirms that we are using the right method," says Erik Larsson.

Chart of viral presence The result of the study is a massive chart of viral presence in cancer. Among other things, the study was able to confirm that liver cancer is often caused by the hepatitis virus, and that the human papilloma virus causes cervical cancer. The study also shows that viral infection also causes major adaptations in the tumour cell, and that virus-positive tumours from widely different organs can therefore display considerable similarities.


Story Source:

The above story is based on materials provided by University of Gothenburg. Note: Materials may be edited for content and length.


Journal Reference:

  1. Ka-Wei Tang, Babak Alaei-Mahabadi, Tore Samuelsson, Magnus Lindh, Erik Larsson. The landscape of viral expression and host gene fusion and adaptation in human cancer. Nature Communications, 2013; 4 DOI: 10.1038/ncomms3513

Cite This Page:

University of Gothenburg. "No viral cause for breast cancer and brain tumors." ScienceDaily. ScienceDaily, 8 October 2013. <www.sciencedaily.com/releases/2013/10/131008102354.htm>.
University of Gothenburg. (2013, October 8). No viral cause for breast cancer and brain tumors. ScienceDaily. Retrieved December 18, 2014 from www.sciencedaily.com/releases/2013/10/131008102354.htm
University of Gothenburg. "No viral cause for breast cancer and brain tumors." ScienceDaily. www.sciencedaily.com/releases/2013/10/131008102354.htm (accessed December 18, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, December 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com
When You Lose Weight, This Is Where The Fat Goes

When You Lose Weight, This Is Where The Fat Goes

Newsy (Dec. 17, 2014) Can fat disappear into thin air? New research finds that during weight loss, over 80 percent of a person's fat molecules escape through the lungs. Video provided by Newsy
Powered by NewsLook.com
Why Your Boss Should Let You Sleep In

Why Your Boss Should Let You Sleep In

Newsy (Dec. 17, 2014) According to research out of the University of Pennsylvania, waking up for work is the biggest factor that causes Americans to lose sleep. Video provided by Newsy
Powered by NewsLook.com
Flu Outbreak Closing Schools in Ohio

Flu Outbreak Closing Schools in Ohio

AP (Dec. 17, 2014) A wave of flu illnesses has forced some Ohio schools to shut down over the past week. State officials confirmed one pediatric flu-related death, a 15-year-old girl in southern Ohio. (Dec. 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins