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Fast, painless alternative to liver biopsie proves accurate, reliable

Date:
October 31, 2013
Source:
Henry Ford Health System
Summary:
A non-invasive alternative to liver biopsy, now the standard method of diagnosing cirrhosis in hepatitis patients, proved very reliable in a national multi-center study.

A non-invasive alternative to liver biopsy, now the standard method of diagnosing cirrhosis in hepatitis patients, proved very reliable in a national multi-center study including Henry Ford Hospital.

The results of the study are good news for chronic hepatitis B and C sufferers who now often undergo repeated and potentially painful liver biopsies as part of their disease management.

The focus of the research was the French-made FibroScan, which was being used in more than 70 countries worldwide when it received approval by the U.S. Food and Drug Administration in April.

The study is being presented at the annual meeting of the American Association for the Study of Liver Diseases being held in Washington, DC, Nov. 1-5.

In liver biopsy, a sample of tissue is most often collected using a needle inserted through the skin and underlying tissue and into the liver. It is widely regarded as safe, but because it's invasive, carries risks ranging from pain and bleeding, to rare instances of death.

FibroScan replaces liver biopsies with a quick and painless procedure similar to the familiar ultrasound tests long used to diagnose and track pregnancy, as well as internal disease.

It's based on a technology called transient elastography, which measures liver "stiffness" to assess the degree of fibrosis -- scarring -- and guide ongoing treatment. The scan is performed as an outpatient procedure, taking only about 15 minutes, and providing immediate results on the degree of liver fibrosis.

To confirm the accuracy of FibroScan -- already established by research studies in Europe and Asia -- the new U.S. research focused on 814 patients with chronic type B and C viral hepatitis. Each was examined using FibroScan followed by liver biopsy, and the results were compared according to several criteria.

"What we found," said Stuart C. Gordon, M.D., director of the Hepatology section at Henry Ford, who participated in the study, "confirms that FibroScan very accurately assesses for the presence of cirrhosis in patients with both types of chronic viral hepatitis. The study also noted that the device "exhibits excellent reproducibility," which makes it a "reasonable alternative" to liver biopsy.


Story Source:

The above story is based on materials provided by Henry Ford Health System. Note: Materials may be edited for content and length.


Cite This Page:

Henry Ford Health System. "Fast, painless alternative to liver biopsie proves accurate, reliable." ScienceDaily. ScienceDaily, 31 October 2013. <www.sciencedaily.com/releases/2013/10/131031124719.htm>.
Henry Ford Health System. (2013, October 31). Fast, painless alternative to liver biopsie proves accurate, reliable. ScienceDaily. Retrieved April 18, 2014 from www.sciencedaily.com/releases/2013/10/131031124719.htm
Henry Ford Health System. "Fast, painless alternative to liver biopsie proves accurate, reliable." ScienceDaily. www.sciencedaily.com/releases/2013/10/131031124719.htm (accessed April 18, 2014).

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