Featured Research

from universities, journals, and other organizations

Beta-blockers before surgery linked to lower risk of heart-related events

Date:
November 18, 2013
Source:
The JAMA Network Journals
Summary:
Giving beta-blocker medication to patients with heart disease undergoing noncardiac surgery appears to be associated with a lower risk of death and major adverse cardiovascular events 30 days after surgery in patients with heart failure or a recent myocardial infarction (MI, heart attack), according to a study.

Giving beta-blocker medication to patients with heart disease undergoing noncardiac surgery appears to be associated with a lower risk of death and major adverse cardiovascular events (MACE) 30 days after surgery in patients with heart failure (HF) or a recent myocardial infarction (MI, heart attack), according to a study published by JAMA Internal Medicine, a JAMA Network publication.

The effect of beta-blockers on the cardiac risk of noncardiac surgery has been controversial, with clinical guidelines encouraging their use amidst criticism that the evidence supporting the practice is weak, the authors write in the study background. These are beta-blockers given by physicians to patients at the time of surgery, not the beta-blockers patients are prescribed to take as a maintenance medication to treat chronic heart disease.

Charlotte Andersson, M.D., Ph.D., of the University Hospital of Copenhagen, Denmark, and colleagues identified patients in nationwide Danish registries who had ischemic heart disease (prior heart attack, angina) with or without HF and with or without a history of MI who underwent noncardiac surgery between October 2004 and December 2009. Researchers measured the association between beta-blocker use and MACE and all-cause mortality.

Of the 28,263 patients with heart disease who had surgery, 7,990 (28.3 percent) had HF and 20,273 (71.1 percent) did not. Beta (β)-blockers were used in 4,262 (53.3 percent) patients with HF and in 7,419 (36.6 percent) patients without HF.

The study findings suggest that among patients with HF, using beta-blockers was associated with a lower risk of MACE and mortality, but among patients without HF there was no association between beta-blocker use and MACE or mortality. Among patients without HF, beta-blocker use was associated with a lower risk of MACE and mortality among those who had a recent MI within the last two years.

"In conclusion, use of β-blockers among patients with ischemic heart disease and HF or recent MI undergoing noncardiac surgery is associated with a substantially decreased risk of major adverse cardiovascular events and all-cause mortality within 30 days after surgery," the authors conclude.


Story Source:

The above story is based on materials provided by The JAMA Network Journals. Note: Materials may be edited for content and length.


Journal Reference:

  1. Charlotte Andersson, Charlotte Mérie, Mads Jørgensen, Gunnar H. Gislason, Christian Torp-Pedersen, Charlotte Overgaard, Lars Køber, Per Føge Jensen, Mark A. Hlatky. Association of β-Blocker Therapy With Risks of Adverse Cardiovascular Events and Deaths in Patients With Ischemic Heart Disease Undergoing Noncardiac Surgery. JAMA Internal Medicine, 2013; DOI: 10.1001/jamainternmed.2013.11349

Cite This Page:

The JAMA Network Journals. "Beta-blockers before surgery linked to lower risk of heart-related events." ScienceDaily. ScienceDaily, 18 November 2013. <www.sciencedaily.com/releases/2013/11/131118162813.htm>.
The JAMA Network Journals. (2013, November 18). Beta-blockers before surgery linked to lower risk of heart-related events. ScienceDaily. Retrieved April 21, 2014 from www.sciencedaily.com/releases/2013/11/131118162813.htm
The JAMA Network Journals. "Beta-blockers before surgery linked to lower risk of heart-related events." ScienceDaily. www.sciencedaily.com/releases/2013/11/131118162813.htm (accessed April 21, 2014).

Share This



More Health & Medicine News

Monday, April 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Nine-Month-Old Baby Can't Open His Mouth

Nine-Month-Old Baby Can't Open His Mouth

Newsy (Apr. 19, 2014) — Nine-month-old Wyatt Scott was born with a rare disorder called congenital trismus, which prevents him from opening his mouth. Video provided by Newsy
Powered by NewsLook.com
'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) — In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) — A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com
Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) — The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins