Featured Research

from universities, journals, and other organizations

Blood vessel tangles in brain best left alone, study suggests

Date:
November 20, 2013
Source:
University of Edinburgh
Summary:
Patients with a condition that causes blood vessels in the brain to form an abnormal tangle could be helped by the findings of new research.

Patients with a condition that causes blood vessels in the brain to form an abnormal tangle could be helped by the findings of new research.

Related Articles


An international patient trial suggests that the safest way of managing arteriovenous malformations (AVM) of the brain is to treat the patient's symptoms only, and not the AVM.

People with an AVM -- causing disrupted blood flow in the brain -- are three times more likely to suffer stroke from the AVM bursting or die within three years if the tangled vessels are treated, researchers found.

An AVM occurs when blood passes directly from arteries to veins -- normally arteries carry blood from the heart to the brain, while veins take blood back in the opposite direction.

More than 200 patients with a brain AVM were followed for 33 months in a trial, which was led in the UK by the University of Edinburgh.

The risks linked to treatment of AVMs were much higher than those associated with leaving them alone, the trial found.

The findings build on previous research showing that annually, only one in every hundred patients with a brain AVM suffer a stroke, and the other 99 per cent do not.

Doctors say that if a brain AVM ruptures, the initial effects are often mild.

Common symptoms of the condition include headaches and epilepsy.

Professor Rustam Al-Shahi Salman, of the University of Edinburgh's Division of Clinical Neurosciences, said: "We have found clear evidence of harm to patients in the short term from treatments to obliterate AVMs that have never bled in the past. Observation of trial participants must continue for at least another five years to find out if this difference persists."


Story Source:

The above story is based on materials provided by University of Edinburgh. Note: Materials may be edited for content and length.


Journal Reference:

  1. J P Mohr, Michael K Parides, Christian Stapf, Ellen Moquete, Claudia S Moy, Jessica R Overbey, Rustam Al-Shahi Salman, Eric Vicaut, William L Young, Emmanuel Houdart, Charlotte Cordonnier, Marco A Stefani, Andreas Hartmann, Rόdiger von Kummer, Alessandra Biondi, Joachim Berkefeld, Catharina J M Klijn, Kirsty Harkness, Richard Libman, Xavier Barreau, Alan J Moskowitz. Medical management with or without interventional therapy for unruptured brain arteriovenous malformations (ARUBA): a multicentre, non-blinded, randomised trial. The Lancet, 2013; DOI: 10.1016/S0140-6736(13)62302-8

Cite This Page:

University of Edinburgh. "Blood vessel tangles in brain best left alone, study suggests." ScienceDaily. ScienceDaily, 20 November 2013. <www.sciencedaily.com/releases/2013/11/131120103615.htm>.
University of Edinburgh. (2013, November 20). Blood vessel tangles in brain best left alone, study suggests. ScienceDaily. Retrieved October 31, 2014 from www.sciencedaily.com/releases/2013/11/131120103615.htm
University of Edinburgh. "Blood vessel tangles in brain best left alone, study suggests." ScienceDaily. www.sciencedaily.com/releases/2013/11/131120103615.htm (accessed October 31, 2014).

Share This



More Health & Medicine News

Friday, October 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Melafind: Spotting Melanoma Without a Biopsy

Melafind: Spotting Melanoma Without a Biopsy

Ivanhoe (Oct. 31, 2014) — The MelaFind device is a pain-free way to check suspicious moles for melanoma, without the need for a biopsy. Video provided by Ivanhoe
Powered by NewsLook.com
Battling Multiple Myeloma

Battling Multiple Myeloma

Ivanhoe (Oct. 31, 2014) — The answer isn’t always found in new drugs – repurposing an ‘old’ drug that could mean better multiple myeloma treatment, and hope. Video provided by Ivanhoe
Powered by NewsLook.com
Chronic Inflammation and Prostate Cancer

Chronic Inflammation and Prostate Cancer

Ivanhoe (Oct. 31, 2014) — New information that is linking chronic inflammation in the prostate and prostate cancer, which may help doctors and patients prevent cancer in the future. Video provided by Ivanhoe
Powered by NewsLook.com
Sickle Cell: Stopping Kids’ Silent Strokes

Sickle Cell: Stopping Kids’ Silent Strokes

Ivanhoe (Oct. 31, 2014) — Blood transfusions are proving crucial to young sickle cell patients by helping prevent strokes, even when there is no outward sign of brain injury. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins