Featured Research

from universities, journals, and other organizations

New materials with potential biomedical applications

Date:
November 21, 2013
Source:
Suomen Akatemia (Academy of Finland)
Summary:
Bisphosphonates are a group of compounds that have become well-known and are extensively used as drugs for treating bone-related diseases, such as osteoporosis. New uses for bisphosphonates have been discovered, and their ability to form physical gels in pure water was reported for the first time in a recent study.

Bisphosphonates are a group of compounds that have become well-known and are extensively used as drugs for treating bone-related diseases, such as osteoporosis. New uses for bisphosphonates were discovered, as their ability to form physical gels in pure water was reported for the first time in a recent study performed in collaboration with the Finnish Universities of Jyväskylä and Eastern Finland.

Related Articles


The gelation tendencies of four bisphosphonates were studied in detail under the baton of Academy Research Fellow Elina Sievänen and her group at Department of Chemistry of University of Jyväskylä. Moreover, the structures of the formed gels were investigated in detail by a wide selection of methods. Docent Manu Lahtinen from Department of Chemistry of University of Jyväskylä contributed significantly in the structural analysis part of the study. The examined bisphosphonates were designed and prepared under the supervision of Professor Jouko Vepsäläinen at the School of Pharmacy of the University of Eastern Finland (Kuopio Campus). The study is part of the doctoral thesis of postgraduate student Aino Alanne from the School of Pharmacy of the University of Eastern Finland.

The current study increases our understanding of the factors affecting on processes leading to gelation and may provide new materials for innovative applications in biomedicine. This kind of materials could, for example, serve as substitutes to restore, maintain, and/or improve the function of bone tissue. Moreover, they might act as scaffolds to mimic the extracellular matrix and provide support for cell adhesion, migration, and proliferation.

The study was published in the prestigious international Journal of Materials Chemistry B: Materials for biology and medicine, and the article was featured in the cover art of issue 45 (2013).

Supramolecular gels are responsive and reversible

Physical, also known as supramolecular, gels form when low molecular mass compounds interact with one another by forming a network, which finally adsorbs the solvent into its structure. Supramolecular gels differ from the traditional chemical (polymeric) gels as being reversible. They can be subjected to a stimulus, e.g. heating, to which they respond by changing forms. After the exposure ceases, the gel is re-formed.

Supramolecular gels have several applications in materials chemistry and optoelectronics. Furthermore, biomaterials based on supramolecular gels may find use in biomedicine, drug delivery, and regenerative medicine.


Story Source:

The above story is based on materials provided by Suomen Akatemia (Academy of Finland). Note: Materials may be edited for content and length.


Journal Reference:

  1. Alanne, A.-L., Lahtinen, M., Löfman, M., Turhanen, P., Kolehmainen, E., Vepsäläinen, J., Sievänen, E. First bisphosphonate hydrogelators: potential composers of biocompatible gels. Journal of Materials Chemistry B., November 2013

Cite This Page:

Suomen Akatemia (Academy of Finland). "New materials with potential biomedical applications." ScienceDaily. ScienceDaily, 21 November 2013. <www.sciencedaily.com/releases/2013/11/131121111802.htm>.
Suomen Akatemia (Academy of Finland). (2013, November 21). New materials with potential biomedical applications. ScienceDaily. Retrieved January 30, 2015 from www.sciencedaily.com/releases/2013/11/131121111802.htm
Suomen Akatemia (Academy of Finland). "New materials with potential biomedical applications." ScienceDaily. www.sciencedaily.com/releases/2013/11/131121111802.htm (accessed January 30, 2015).

Share This


More From ScienceDaily



More Matter & Energy News

Friday, January 30, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Tesla 'Insane Mode' Gives Unsuspecting Passengers the Ride of Their Life

Tesla 'Insane Mode' Gives Unsuspecting Passengers the Ride of Their Life

RightThisMinute (Jan. 29, 2015) — If your car has an "Insane Mode" then you know it&apos;s fast. Well, these unsuspecting passengers were in for one insane ride when they hit the button. Tesla cars are awesome. Video provided by RightThisMinute
Powered by NewsLook.com
Now Bill Gates Is 'Concerned' About Artificial Intelligence

Now Bill Gates Is 'Concerned' About Artificial Intelligence

Newsy (Jan. 29, 2015) — Bill Gates joins the list of tech moguls scared of super-intelligent machines. He says more people should be concerned, but why? Video provided by Newsy
Powered by NewsLook.com
Senate Passes Bill for Keystone XL Pipeline

Senate Passes Bill for Keystone XL Pipeline

AP (Jan. 29, 2015) — The Republican-controlled Senate has passed a bipartisan bill approving construction of the Keystone XL oil pipeline. (Jan. 29) Video provided by AP
Powered by NewsLook.com
Two Stunt Pilots Perform Incredibly Close Flyby

Two Stunt Pilots Perform Incredibly Close Flyby

Rumble (Jan. 29, 2015) — Two pilots from &apos;Escuadrilla Argentina de Acrobacia Aérea&apos; perform an incredibly low altitude flyby stunt during a recent show exhibition in Argentina. Check it out! Video provided by Rumble
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Space & Time

Matter & Energy

Computers & Math

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins