Featured Research

from universities, journals, and other organizations

Bronchial thermoplasty shows long-term effectiveness for asthma

Date:
December 2, 2013
Source:
National Jewish Health
Summary:
The beneficial effects of bronchial thermoplasty, a non-pharmacologic treatment for asthma, last at least five years, according to researchers. The therapy, in which heat is applied to a patient's airways during a bronchoscopy procedure, was approved by the FDA in 2010. The researchers report that reductions in severe asthma exacerbations, emergency department visits, medication use and missed workdays continued out to five years after the procedure was performed.

The beneficial effects of bronchial thermoplasty, a non-pharmacologic treatment for asthma, last at least five years, according to researchers at National Jewish Health and other institutions. The therapy, in which heat is applied to a patient's airways during a bronchoscopy procedure, was approved by the U.S. Food and Drug Administration in April 2010. Among other criteria, the researchers report in the December issue of the Journal of Allergy and Clinical Immunology that reductions in severe asthma exacerbations, emergency department visits, medication use and missed workdays continued out to five years after the procedure was performed.

"These data add to the growing body of evidence that bronchial thermoplasty has a long-term benefit and is an important option for patients whose moderate to severe asthma is not controlled by medications," said Michael Wechsler, MD, lead author of the study and professor of medicine at National Jewish Health.

During bronchial thermoplasty a physician uses a specialized bronchoscope to apply radio frequency energy to heat the airways. The treatment is done in three separate procedures approximately three weeks apart, and reduces smooth muscle surrounding the airways, which can constrict and reduce airflow in asthma.

Earlier research showed that most patients who underwent bronchial thermoplasty in the AIR2 trial experienced benefits for at least two years. The current study extends that to five years.

In the year before bronchial thermoplasty, 52 percent of patients suffered severe exacerbations of their asthma. That dropped to 31 percent in the first year following the treatment and averaged 29 percent over the five years following the procedure.

After bronchial thermoplasty 78 percent fewer patients made visits to the emergency department, dropping from about 30 percent of patients to less than 7 percent.

Missed workdays dropped 66 percent in the five years after bronchial thermoplasty. Average use of corticosteroid medications also dropped 17 percent.

Stable rates of respiratory adverse events and respiratory-related hospitalizations as well as unchanged CT scans in years two through five indicated that there were no significant safety concerns with the procedure.


Story Source:

The above story is based on materials provided by National Jewish Health. Note: Materials may be edited for content and length.


Journal Reference:

  1. Michael E. Wechsler, Michel Laviolette, Adalberto S. Rubin, Jussara Fiterman, Jose R. Lapa e Silva, Pallav L. Shah, Elie Fiss, Ronald Olivenstein, Neil C. Thomson, Robert M. Niven, Ian D. Pavord, Michael Simoff, Jeff B. Hales, Charlene McEvoy, Dirk-Jan Slebos, Mark Holmes, Martin J. Phillips, Serpil C. Erzurum, Nicola A. Hanania, Kaharu Sumino, Monica Kraft, Gerard Cox, Daniel H. Sterman, Kyle Hogarth, Joel N. Kline, Adel H. Mansur, Brian E. Louie, William M. Leeds, Richard G. Barbers, John H.M. Austin, Narinder S. Shargill, John Quiring, Brian Armstrong, Mario Castro. Bronchial thermoplasty: Long-term safety and effectiveness in patients with severe persistent asthma. Journal of Allergy and Clinical Immunology, 2013; 132 (6): 1295 DOI: 10.1016/j.jaci.2013.08.009

Cite This Page:

National Jewish Health. "Bronchial thermoplasty shows long-term effectiveness for asthma." ScienceDaily. ScienceDaily, 2 December 2013. <www.sciencedaily.com/releases/2013/12/131202142737.htm>.
National Jewish Health. (2013, December 2). Bronchial thermoplasty shows long-term effectiveness for asthma. ScienceDaily. Retrieved September 23, 2014 from www.sciencedaily.com/releases/2013/12/131202142737.htm
National Jewish Health. "Bronchial thermoplasty shows long-term effectiveness for asthma." ScienceDaily. www.sciencedaily.com/releases/2013/12/131202142737.htm (accessed September 23, 2014).

Share This



More Health & Medicine News

Tuesday, September 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Liberia Pleads for Help to Fight Ebola

Liberia Pleads for Help to Fight Ebola

AP (Sep. 22, 2014) Liberia's finance minister is urging the international community to quickly follow through on pledges of cash to battle Ebola. Bodies are piling up in the capital Monrovia as the nation awaits more help. (Sept. 22) Video provided by AP
Powered by NewsLook.com
Ebola Doctor Says Border Controls Critical

Ebola Doctor Says Border Controls Critical

AP (Sep. 22, 2014) A Florida doctor who helped fight the expanding Ebola outbreak in West Africa says the disease can be stopped, but only if nations quickly step up their response and make border control a priority. (Sept. 22) Video provided by AP
Powered by NewsLook.com
Global Ebola Aid Increasing But Critics Say It's Late

Global Ebola Aid Increasing But Critics Say It's Late

Newsy (Sep. 21, 2014) More than 100 tons of medical supplies were sent to West Africa on Saturday, but aid workers say the global response is still sluggish. Video provided by Newsy
Powered by NewsLook.com
Sierra Leone in Lockdown to Control Ebola

Sierra Leone in Lockdown to Control Ebola

AP (Sep. 21, 2014) Sierra Leone residents remained in lockdown on Saturday as part of a massive effort to confine millions of people to their homes in a bid to stem the biggest Ebola outbreak in history. (Sept. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins