Featured Research

from universities, journals, and other organizations

Laser ablation surgery shows better cognitive results for people with epilepsy

Date:
December 8, 2013
Source:
American Epilepsy Society (AES)
Summary:
MRI-Guided Stereotactic Laser Ablation (SLA) of the hippocampus to control seizures in people with temporal lobe epilepsy (TLE) may result in seizure control that approaches that from anterior temporal lobectory or selective amygdalohippocampectomy and better cognitive outcomes than any of the standard open resections, according to a study. If the SLA continues to prove safe and shows adequate efficacy for seizure control, the technique has the potential to drastically change brain surgery.

MRI-Guided Stereotactic Laser Ablation (SLA) of the hippocampus to control seizures in people with temporal lobe epilepsy (TLE) may result in seizure control that approaches that from anterior temporal lobectory or selective amygdalohippocampectomy and better cognitive outcomes than any of the standard open resections, according to a study presented at the American Epilepsy Society’s 67th Annual Meeting in Washington DC. If the SLA continues to prove safe and shows adequate efficacy for seizure control, the technique has the potential to drastically change brain surgery.

Stereotactic laser ablation is a brain surgery technique that preserves more brain regions and interconnections. Traditional surgery, such as amygdalohippocampectomy, typically requires a fairly large resection that cuts through other temporal lobe regions and white matter pathways. This resection approach results in cognitive morbidity involving potential deficits in material-specific memory and visual confrontational naming.

Using pre- and post-surgical neuropsychological data at 6-months following surgery, the research compared the cognitive outcomes for 10 people with TLE who had standard surgical treatment with the cognitive outcomes of 7 patients who underwent SLA for TLE. The study found that the cognitive declines were less following laser ablation than standard approaches. In addition to the cognitive benefits, the SLA technique is minimally invasive and is therefore more cosmetically appealing and involves less discomfort. It also decreases the length of hospital stay.

The study found that there was no decline in episodic memory following laser ablation, although such decline was often seen in patients undergoing standard open resections. In addition, patients undergoing SLA were more likely to exhibit improved memory functioning than standard resection patients, which the study attributes to greater preservation of additional brain regions and connections.

“Given the presumed importance of the hippocampus in episodic memory, we were surprised by the absence of any decline in the SLA group. This suggests that our understanding of the function of this brain structure may be incomplete, and that being able to perform such a precise resection may help us learn more about brain regions in a manner that was never before possible in humans. Overall, from a clinical standpoint, if we continue to see better outcomes in patients undergoing SLA, this technique could have a huge impact in brain surgery,” said Daniel Drane, Ph.D., Emory University School of Medicine.


Story Source:

The above story is based on materials provided by American Epilepsy Society (AES). Note: Materials may be edited for content and length.


Cite This Page:

American Epilepsy Society (AES). "Laser ablation surgery shows better cognitive results for people with epilepsy." ScienceDaily. ScienceDaily, 8 December 2013. <www.sciencedaily.com/releases/2013/12/131208090251.htm>.
American Epilepsy Society (AES). (2013, December 8). Laser ablation surgery shows better cognitive results for people with epilepsy. ScienceDaily. Retrieved August 20, 2014 from www.sciencedaily.com/releases/2013/12/131208090251.htm
American Epilepsy Society (AES). "Laser ablation surgery shows better cognitive results for people with epilepsy." ScienceDaily. www.sciencedaily.com/releases/2013/12/131208090251.htm (accessed August 20, 2014).

Share This




More Mind & Brain News

Wednesday, August 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Do More Wedding Guests Make A Happier Marriage?

Do More Wedding Guests Make A Happier Marriage?

Newsy (Aug. 20, 2014) — A new study found couples who had at least 150 guests at their weddings were more likely to report being happy in their marriages. Video provided by Newsy
Powered by NewsLook.com
Charter Schools Alter Post-Katrina Landscape

Charter Schools Alter Post-Katrina Landscape

AP (Aug. 20, 2014) — Nine years after Hurricane Katrina, charter schools are the new reality of public education in New Orleans. The state of Louisiana took over most of the city's public schools after the killer storm in 2005. (Aug. 20) Video provided by AP
Powered by NewsLook.com
Researcher Testing on-Field Concussion Scanners

Researcher Testing on-Field Concussion Scanners

AP (Aug. 19, 2014) — Four Texas high school football programs are trying out an experimental system designed to diagnose concussions on the field. The technology is in response to growing concern over head trauma in America's most watched sport. (Aug. 19) Video provided by AP
Powered by NewsLook.com
Kids' Drawings At Age 4 Linked To Intelligence At Age 14

Kids' Drawings At Age 4 Linked To Intelligence At Age 14

Newsy (Aug. 19, 2014) — A study by King's College London says there's a link between how well kids draw at age 4 and how intelligent they are later in life. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins