Featured Research

from universities, journals, and other organizations

Standardized protocol, surgery improve mortality outcomes for stroke victims

Date:
January 27, 2014
Source:
Mayo Clinic
Summary:
For patients who have experienced a large stroke that cuts off blood supply to a large part of the brain, the use of standardized medical management protocol and surgery to decompress swelling can improve life expectancy, researchers found in a recent study.

For patients who have experienced a large stroke that cuts off blood supply to a large part of the brain, the use of standardized medical management protocol and surgery to decompress swelling can improve life expectancy, Mayo Clinic researchers found in a recent study.

The medical protocol provided each patient with consistent procedures for airway management, ventilator settings, blood pressure control, fluid and electrolyte management, gastrointestinal and nutritional management, hematologic monitoring and management, intracranial pressure monitoring, sedation, use of medication, anticonvulsants, prevention against deep-vein thrombosis and rehabilitation.

Surgery involved removing a large portion of the skull over the area of the stroke to provide extra room for the brain swelling. This reduced pressure in the head and risk of death. For surviving patients, the piece of skull was replaced via a second surgery after the brain swelling had resolved.

"We discovered who -- out of this patient group -- was most at risk for mortality. We also determined that by using a standardized medical protocol -- in other words, treating every patient in the exact same way and preparing for each issue we may encounter -- we were able to reduce patient mortality by about 50 percent," says Douglas Chyatte, M.D., a study author and neurosurgeon at Mayo Clinic Health System. "In addition, when we examined surgery, there was a positive trend in reducing mortality in this group of patients.

Stroke is the fourth leading cause of death in the United States, according to the Centers for Disease Control and Prevention. As many as 80 percent of patients with large supratentorial hemispheric infarction strokes die, but research by Mayo Clinic and other medical experts has uncovered ways to significantly reduce deaths in these patients. The findings are published in the American Heart Association Stroke Journal.

The researchers screened nearly 5,000 stroke patients to determine eligibility for the study. About 70 patients were eligible based on their diagnosis of a large supratentorial hemispheric infarction stroke, and 40 enrolled in the study. All enrolled patients were treated using the standardized medical treatment protocol, and patients with more severe conditions received further medical treatment or further medical treatment plus surgery.


Story Source:

The above story is based on materials provided by Mayo Clinic. Note: Materials may be edited for content and length.


Journal Reference:

  1. J. I. Frank, L. P. Schumm, K. Wroblewski, D. Chyatte, A. J. Rosengart, C. Kordeck, R. A. Thisted, G. Bernardini, J. Andrefsky, D. Krieger, M. Elkind, W. Coplin, C. Graffagnino, J. Biller, D. Wang, S. Cruz-Flores, D. Brock, A. Demchuk, P. Verro, J. Frank, D. Woo, J. Suarez, C. Pettigrew, M. LaMonte. Hemicraniectomy and Durotomy Upon Deterioration From Infarction-Related Swelling Trial: Randomized Pilot Clinical Trial. Stroke, 2014; DOI: 10.1161/%u200BSTROKEAHA.113.003200

Cite This Page:

Mayo Clinic. "Standardized protocol, surgery improve mortality outcomes for stroke victims." ScienceDaily. ScienceDaily, 27 January 2014. <www.sciencedaily.com/releases/2014/01/140127122152.htm>.
Mayo Clinic. (2014, January 27). Standardized protocol, surgery improve mortality outcomes for stroke victims. ScienceDaily. Retrieved September 3, 2014 from www.sciencedaily.com/releases/2014/01/140127122152.htm
Mayo Clinic. "Standardized protocol, surgery improve mortality outcomes for stroke victims." ScienceDaily. www.sciencedaily.com/releases/2014/01/140127122152.htm (accessed September 3, 2014).

Share This



More Health & Medicine News

Wednesday, September 3, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Snack Attack: Study Says Action Movies Make You Snack More

Snack Attack: Study Says Action Movies Make You Snack More

Newsy (Sep. 2, 2014) You're more likely to gain weight while watching action flicks than you are watching other types of programming, says a new study published in JAMA. Video provided by Newsy
Powered by NewsLook.com
U.N. Says Ebola Travel Restrictions Will Cause Food Shortage

U.N. Says Ebola Travel Restrictions Will Cause Food Shortage

Newsy (Sep. 2, 2014) The U.N. says the problem is two-fold — quarantine zones and travel restrictions are limiting the movement of both people and food. Video provided by Newsy
Powered by NewsLook.com
Doctors Fear They're Losing Battle Against Ebola

Doctors Fear They're Losing Battle Against Ebola

AP (Sep. 2, 2014) As a third American missionary is confirmed to have contracted Ebola in Liberia, doctors on the ground in West Africa fear they're losing the battle against the outbreak. (Sept. 2) Video provided by AP
Powered by NewsLook.com
Tech Giants Bet on 3D Headsets for Gaming, Healthcare

Tech Giants Bet on 3D Headsets for Gaming, Healthcare

AFP (Sep. 2, 2014) When Facebook acquired the virtual reality hardware developer Oculus VR in March for $2 billion, CEO Mark Zuckerberg hailed the firm's technology as "a new communication platform." Duration: 02:24 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins