Featured Research

from universities, journals, and other organizations

Heart transplant success improving, patients living longer

Date:
January 30, 2014
Source:
Society of Thoracic Surgeons
Summary:
Heart transplantation continues to be the “gold standard” treatment for end-stage heart failure, and a large number of patients now live 20 years or more after surgery.

Heart transplantation continues to be the "gold standard" treatment for end-stage heart failure, and a large number of patients now live 20 years or more after surgery, according to a study in the February 2014 issue of The Annals of Thoracic Surgery.

Hector Rodriguez Cetina Biefer, MD and Markus J. Wilhelm, MD, from the University Hospital Zurich in Switzerland, led a research team that examined long-term outcomes in 133 patients from their institution who underwent heart transplantation from 1985 to 1991.

Among those patients, 74 (55.6%) survived at least 20 years post-transplantation. The average age at transplant for the 20-year survivors was 43.6 years.

Major causes of death in non-survivors were graft rejection (21%), malignancy (21%), cardiac allograft vasculopathy (an accelerated form of coronary artery disease; 14.5%), and infections (14.5%).

"A remarkable number of patients survived 20 years or more following heart transplantation, confirming the procedure as the 'gold standard' for end-stage heart failure, at least for the time being," said Dr. Wilhelm. "With continued improvements in immunosuppressive management in the coming years, we expect to see transplant patients living longer, healthier lives. It is still uncertain if mechanical circulatory support devices will be able to compete with heart transplantation in the future."

Heart Transplantation Changed the Course of Cardiac Care In an invited commentary in the same issue of The Annals, James Kirklin, MD, from the University of Alabama in Birmingham, discussed the success of heart transplantation as a treatment for end-stage heart disease and the changes the procedure brought to cardiac care.

"This study underscores the excellent long-term survival that can be achieved, even among patients who received a transplant in the early 1990s," said Dr. Kirklin. "The fact that over half of patients were alive 20 years later should provide hope and the expectation that a new heart for most patients really is a 'new lease on life.' If patients take care of themselves, they can expect to have many years of good quality of life."

He added that heart transplantation set the stage for other complex cardiac surgery endeavors. "Despite the limited number of patients who have received a transplant for end-stage heart disease, this procedure and the multifaceted discipline it introduced have had far-reaching effects on the field of cardiac surgery," said Dr. Kirklin.


Story Source:

The above story is based on materials provided by Society of Thoracic Surgeons. Note: Materials may be edited for content and length.


Journal Reference:

  1. Hector Rodriguez Cetina Biefer, Simon H. Sόndermann, Maximilian Y. Emmert, Frank Enseleit, Burkhardt Seifert, Frank Ruschitzka, Stephan Jacobs, Mario L. Lachat, Volkmar Falk, Markus J. Wilhelm. Surviving 20 Years After Heart Transplantation: A Success Story. The Annals of Thoracic Surgery, 2014; 97 (2): 499 DOI: 10.1016/j.athoracsur.2013.08.040

Cite This Page:

Society of Thoracic Surgeons. "Heart transplant success improving, patients living longer." ScienceDaily. ScienceDaily, 30 January 2014. <www.sciencedaily.com/releases/2014/01/140130040653.htm>.
Society of Thoracic Surgeons. (2014, January 30). Heart transplant success improving, patients living longer. ScienceDaily. Retrieved July 24, 2014 from www.sciencedaily.com/releases/2014/01/140130040653.htm
Society of Thoracic Surgeons. "Heart transplant success improving, patients living longer." ScienceDaily. www.sciencedaily.com/releases/2014/01/140130040653.htm (accessed July 24, 2014).

Share This




More Health & Medicine News

Thursday, July 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Idaho Boy Helps Brother With Disabilities Complete Triathlon

Idaho Boy Helps Brother With Disabilities Complete Triathlon

Newsy (July 23, 2014) — An 8-year-old boy helped his younger brother, who has a rare genetic condition that's confined him to a wheelchair, finish a triathlon. Video provided by Newsy
Powered by NewsLook.com
Thousands Who Can't Afford Medical Care Flock to Free US Clinic

Thousands Who Can't Afford Medical Care Flock to Free US Clinic

AFP (July 23, 2014) — America may be the world’s richest country, but in terms of healthcare, the World Health Organisation ranks it 37th. Thousands turned out for a free clinic run by "Remote Area Medical" with a visit from the Governor of Virginia. Duration: 2:40 Video provided by AFP
Powered by NewsLook.com
Stone Fruit Listeria Scare Causes Sweeping Recall

Stone Fruit Listeria Scare Causes Sweeping Recall

Newsy (July 22, 2014) — The Wawona Packing Company has issued a voluntary recall on the stone fruit it distributes due to a possible Listeria outbreak. Video provided by Newsy
Powered by NewsLook.com
Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Newsy (July 22, 2014) — The 83 new genetic markers could open dozens of new avenues for schizophrenia treatment research. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins