Featured Research

from universities, journals, and other organizations

Prediction modeling may lead to more personalized heart care for patients

Date:
January 30, 2014
Source:
Society of Thoracic Surgeons
Summary:
Detailed prediction models that project long-term patient mortality following PCI and CABG surgery can be useful for the heart team when determining the best treatment strategy for individual patients.

Detailed prediction models that project long-term patient mortality following percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) surgery can be useful for the heart team when determining the best treatment strategy for individual patients, according to a study in the February 2014 issue of The Annals of Thoracic Surgery.

"One problem with cardiovascular care today is that PCI and CABG are viewed as competitive procedures," said Joseph F. Sabik III, MD. "Our study attempts to show that these procedures should instead be seen as complementary. Depending on patient comorbidities and extent of coronary artery disease, some patients have better survival after CABG, while other patients experience better outcomes following PCI."

Dr. Sabik and researchers from the Cleveland Clinic in Ohio used patient data from two registries to develop survival models for CABG and PCI. CABG is a surgical procedure in which arteries or veins from elsewhere in the body are grafted to the coronary arteries, bypassing the narrowed or blocked area to improve blood supply. PCI involves non-surgical procedures, such as balloon angioplasty or stent placement, to open narrowed coronary arteries.

From 1995 to 2007, 13,114 patients at the Cleveland Clinic underwent CABG surgery, 6,964 underwent PCI with bare-metal stents (BMS), and 3,104 underwent PCI with drug-eluting stents (DES). Survival models were developed independently for each therapy, and all factors appearing in any of the three models were then programmed into a decision-support tool, which enabled researchers to examine long-term survival rates for each procedure.

Analysis showed that patients with more extensive coronary artery disease and those who had more comorbidities experienced better outcomes after undergoing CABG surgery, while patients who had acute myocardial infarction (heart attack) or had more limited coronary artery disease had better long-term outcomes after PCI.

"Our study suggests that patients should be more engaged in their own health care decisions," said Dr. Sabik. "When meeting with their surgeon or physician, patients should ask how the treatment strategy was determined -- Did they consult with a heart team, and did they consider both PCI and surgery?"

The heart team involves a team-based approach to cardiac care connecting the patient to many practitioners, including primary cardiologists, interventional cardiologists, cardiac surgeons, imaging specialists, and nurses, among others.

Importance of Comprehensive Approach to Patient Care In an invited commentary in the same issue of The Annals, A. Pieter Kappetein, MD, PhD and Ruben Osnabrugge, MD, from Erasmus MC in Rotterdam, The Netherlands, commented on the need for a risk-benefit analysis to be used in conjunction with a heart team approach for patient care. "Treatment models help physicians make recommendations, but a heart team approach to individualize treatment is needed to ensure that every patient receives the optimal therapy," said Dr. Kappetein.

"This study provides an example of how treatment models can be used to predict long-term outcomes after PCI and CABG in patients with aortic stenosis," said Dr. Kappetein. "Hopefully future models also will be able to predict outcomes in addition to just mortality."


Story Source:

The above story is based on materials provided by Society of Thoracic Surgeons. Note: Materials may be edited for content and length.


Journal Reference:

  1. Sajjad Raza, Joseph F. Sabik, Stephen G. Ellis, Penny L. Houghtaling, Kerry C. Rodgers, Aleck Stockins, Bruce W. Lytle, Eugene H. Blackstone. Survival Prediction Models for Coronary Intervention: Strategic Decision Support. The Annals of Thoracic Surgery, 2014; 97 (2): 522 DOI: 10.1016/j.athoracsur.2013.06.099

Cite This Page:

Society of Thoracic Surgeons. "Prediction modeling may lead to more personalized heart care for patients." ScienceDaily. ScienceDaily, 30 January 2014. <www.sciencedaily.com/releases/2014/01/140130040655.htm>.
Society of Thoracic Surgeons. (2014, January 30). Prediction modeling may lead to more personalized heart care for patients. ScienceDaily. Retrieved July 31, 2014 from www.sciencedaily.com/releases/2014/01/140130040655.htm
Society of Thoracic Surgeons. "Prediction modeling may lead to more personalized heart care for patients." ScienceDaily. www.sciencedaily.com/releases/2014/01/140130040655.htm (accessed July 31, 2014).

Share This




More Health & Medicine News

Thursday, July 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
Concern Grows Over Worsening Ebola Crisis

Concern Grows Over Worsening Ebola Crisis

AFP (July 30, 2014) Pan-African airline ASKY has suspended all flights to and from the capitals of Liberia and Sierra Leone amid the worsening Ebola health crisis, which has so far caused 672 deaths in Guinea, Liberia and Sierra Leone. Duration: 00:43 Video provided by AFP
Powered by NewsLook.com
At Least 20 Chikungunya Cases in New Jersey

At Least 20 Chikungunya Cases in New Jersey

AP (July 30, 2014) At least 20 New Jersey residents have tested positive for chikungunya, a mosquito-borne virus that has spread through the Caribbean. (July 30) Video provided by AP
Powered by NewsLook.com
Xtreme Eating: Your Daily Caloric Intake All On One Plate

Xtreme Eating: Your Daily Caloric Intake All On One Plate

Newsy (July 30, 2014) The Center for Science in the Public Interest released its 2014 list of single meals with whopping calorie counts. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

    Technology News



      Save/Print:
      Share:

      Free Subscriptions


      Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

      Get Social & Mobile


      Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

      Have Feedback?


      Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
      Mobile: iPhone Android Web
      Follow: Facebook Twitter Google+
      Subscribe: RSS Feeds Email Newsletters
      Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins