Featured Research

from universities, journals, and other organizations

Vitamin D provides relief for those with chronic hives, study shows

Date:
February 17, 2014
Source:
University of Nebraska Medical Center (UNMC)
Summary:
Vitamin D as an add-on therapy could provide some relief for chronic hives, a condition with no cure and few treatment options, new research indicates. An allergic skin condition, chronic hives create red, itchy welts on the skin and sometimes swelling. They can occur daily and last longer than six weeks, even years. The two-year study looked at the role of over-the-counter vitamin D3 as a supplemental treatment for chronic hives. Over 12 weeks, 38 study participants daily took a triple-drug combination of allergy medications (one prescription and two over-the-counter drugs) and vitamin D3. Researchers found after just one week, the severity of patients' symptoms decreased by 33 percent. For patients that took a stronger dose of vitamin D3, a further 40 percent decrease in severity of their hives was noted.

A study by researchers at the University of Nebraska Medical Center shows vitamin D as an add-on therapy could provide some relief for chronic hives, a condition with no cure and few treatment options. An allergic skin condition, chronic hives create red, itchy welts on the skin and sometimes swelling. They can occur daily and last longer than six weeks, even years.

Jill Poole, M.D., associate professor in the UNMC Department of Internal Medicine, was principal investigator of a study in the Feb. 7 edition of the Annals of Allergy, Asthma and Immunology. The two-year study looked at the role of over-the-counter vitamin D3 as a supplemental treatment for chronic hives.

Over 12 weeks, 38 study participants daily took a triple-drug combination of allergy medications (one prescription and two over-the-counter drugs) and one vitamin D3, an over-the-counter supplement. Half of the patient's took 600 IUs of vitamin D3 and the other half took 4000 IUs.

Researchers found after just one week, the severity of patients' symptoms decreased by 33 percent for both groups. But at the end of three months, the group taking 4000 IUs of vitamin D3 had a further 40 percent decrease in severity of their hives. The low vitamin D3 treatment group had no further improvement after the first week.

"We consider the results in patients a significant improvement," Dr. Poole said. "This higher dosing of readily available vitamin D3 shows promise without adverse effects. Vitamin D3 could be considered a safe and potentially beneficial therapy.

"It was not a cure, but it showed benefit when added to anti-allergy medications. Patients taking the higher dose had less severe hives -- they didn't have as many hives and had a decrease in the number of days a week they had hives.

In the study, patients had suffered from five to 20 years with severe hives. Some had been on therapy and others none.

The cause of hives is not generally known, but allergy and autoimmune reactions sometimes play a role. Treatment options for chronic hives are limited.

"Standard therapy is to control symptoms with antihistamines and other allergy medications," Dr. Poole said. "Some are costly and can pose substantial side effects."

She said the study didn't include patients with kidney disease or those with calcium disorders.


Story Source:

The above story is based on materials provided by University of Nebraska Medical Center (UNMC). Note: Materials may be edited for content and length.


Journal Reference:

  1. Andy Rorie, Whitney S. Goldner, Elizabeth Lyden, Jill A. Poole. Beneficial role for supplemental vitamin D3 treatment in chronic urticaria: a randomized study. Annals of Allergy, Asthma & Immunology, 2014; DOI: 10.1016/j.anai.2014.01.010

Cite This Page:

University of Nebraska Medical Center (UNMC). "Vitamin D provides relief for those with chronic hives, study shows." ScienceDaily. ScienceDaily, 17 February 2014. <www.sciencedaily.com/releases/2014/02/140217084804.htm>.
University of Nebraska Medical Center (UNMC). (2014, February 17). Vitamin D provides relief for those with chronic hives, study shows. ScienceDaily. Retrieved July 25, 2014 from www.sciencedaily.com/releases/2014/02/140217084804.htm
University of Nebraska Medical Center (UNMC). "Vitamin D provides relief for those with chronic hives, study shows." ScienceDaily. www.sciencedaily.com/releases/2014/02/140217084804.htm (accessed July 25, 2014).

Share This




More Health & Medicine News

Friday, July 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

AFP (July 24, 2014) A so-called drugs rehab 'clinic' is closed down in Pakistan after police find scores of ‘patients’ chained up alleging serial abuse. Duration 03:05 Video provided by AFP
Powered by NewsLook.com
Too Few Teens Receiving HPV Vaccination, CDC Says

Too Few Teens Receiving HPV Vaccination, CDC Says

Newsy (July 24, 2014) The Centers for Disease Control and Prevention is blaming doctors for the low number of children being vaccinated for HPV. Video provided by Newsy
Powered by NewsLook.com
New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Newsy (July 24, 2014) Sheik Umar Khan has treated many of the people infected in the Ebola outbreak, and now he's become one of them. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

    Health News

      Environment News

        Technology News



          Save/Print:
          Share:

          Free Subscriptions


          Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

          Get Social & Mobile


          Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

          Have Feedback?


          Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
          Mobile: iPhone Android Web
          Follow: Facebook Twitter Google+
          Subscribe: RSS Feeds Email Newsletters
          Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins