Featured Research

from universities, journals, and other organizations

Vitamin D provides relief for those with chronic hives, study shows

Date:
February 17, 2014
Source:
University of Nebraska Medical Center (UNMC)
Summary:
Vitamin D as an add-on therapy could provide some relief for chronic hives, a condition with no cure and few treatment options, new research indicates. An allergic skin condition, chronic hives create red, itchy welts on the skin and sometimes swelling. They can occur daily and last longer than six weeks, even years. The two-year study looked at the role of over-the-counter vitamin D3 as a supplemental treatment for chronic hives. Over 12 weeks, 38 study participants daily took a triple-drug combination of allergy medications (one prescription and two over-the-counter drugs) and vitamin D3. Researchers found after just one week, the severity of patients' symptoms decreased by 33 percent. For patients that took a stronger dose of vitamin D3, a further 40 percent decrease in severity of their hives was noted.

A study by researchers at the University of Nebraska Medical Center shows vitamin D as an add-on therapy could provide some relief for chronic hives, a condition with no cure and few treatment options. An allergic skin condition, chronic hives create red, itchy welts on the skin and sometimes swelling. They can occur daily and last longer than six weeks, even years.

Jill Poole, M.D., associate professor in the UNMC Department of Internal Medicine, was principal investigator of a study in the Feb. 7 edition of the Annals of Allergy, Asthma and Immunology. The two-year study looked at the role of over-the-counter vitamin D3 as a supplemental treatment for chronic hives.

Over 12 weeks, 38 study participants daily took a triple-drug combination of allergy medications (one prescription and two over-the-counter drugs) and one vitamin D3, an over-the-counter supplement. Half of the patient's took 600 IUs of vitamin D3 and the other half took 4000 IUs.

Researchers found after just one week, the severity of patients' symptoms decreased by 33 percent for both groups. But at the end of three months, the group taking 4000 IUs of vitamin D3 had a further 40 percent decrease in severity of their hives. The low vitamin D3 treatment group had no further improvement after the first week.

"We consider the results in patients a significant improvement," Dr. Poole said. "This higher dosing of readily available vitamin D3 shows promise without adverse effects. Vitamin D3 could be considered a safe and potentially beneficial therapy.

"It was not a cure, but it showed benefit when added to anti-allergy medications. Patients taking the higher dose had less severe hives -- they didn't have as many hives and had a decrease in the number of days a week they had hives.

In the study, patients had suffered from five to 20 years with severe hives. Some had been on therapy and others none.

The cause of hives is not generally known, but allergy and autoimmune reactions sometimes play a role. Treatment options for chronic hives are limited.

"Standard therapy is to control symptoms with antihistamines and other allergy medications," Dr. Poole said. "Some are costly and can pose substantial side effects."

She said the study didn't include patients with kidney disease or those with calcium disorders.


Story Source:

The above story is based on materials provided by University of Nebraska Medical Center (UNMC). Note: Materials may be edited for content and length.


Journal Reference:

  1. Andy Rorie, Whitney S. Goldner, Elizabeth Lyden, Jill A. Poole. Beneficial role for supplemental vitamin D3 treatment in chronic urticaria: a randomized study. Annals of Allergy, Asthma & Immunology, 2014; DOI: 10.1016/j.anai.2014.01.010

Cite This Page:

University of Nebraska Medical Center (UNMC). "Vitamin D provides relief for those with chronic hives, study shows." ScienceDaily. ScienceDaily, 17 February 2014. <www.sciencedaily.com/releases/2014/02/140217084804.htm>.
University of Nebraska Medical Center (UNMC). (2014, February 17). Vitamin D provides relief for those with chronic hives, study shows. ScienceDaily. Retrieved September 22, 2014 from www.sciencedaily.com/releases/2014/02/140217084804.htm
University of Nebraska Medical Center (UNMC). "Vitamin D provides relief for those with chronic hives, study shows." ScienceDaily. www.sciencedaily.com/releases/2014/02/140217084804.htm (accessed September 22, 2014).

Share This



More Health & Medicine News

Monday, September 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Liberia Pleads for Help to Fight Ebola

Liberia Pleads for Help to Fight Ebola

AP (Sep. 22, 2014) Liberia's finance minister is urging the international community to quickly follow through on pledges of cash to battle Ebola. Bodies are piling up in the capital Monrovia as the nation awaits more help. (Sept. 22) Video provided by AP
Powered by NewsLook.com
Global Ebola Aid Increasing But Critics Say It's Late

Global Ebola Aid Increasing But Critics Say It's Late

Newsy (Sep. 21, 2014) More than 100 tons of medical supplies were sent to West Africa on Saturday, but aid workers say the global response is still sluggish. Video provided by Newsy
Powered by NewsLook.com
Sierra Leone in Lockdown to Control Ebola

Sierra Leone in Lockdown to Control Ebola

AP (Sep. 21, 2014) Sierra Leone residents remained in lockdown on Saturday as part of a massive effort to confine millions of people to their homes in a bid to stem the biggest Ebola outbreak in history. (Sept. 20) Video provided by AP
Powered by NewsLook.com
Sierra Leone's Nationwide Ebola Curfew Underway

Sierra Leone's Nationwide Ebola Curfew Underway

Newsy (Sep. 20, 2014) Sierra Leone is locked down as aid workers and volunteers look for new cases of Ebola. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins