Featured Research

from universities, journals, and other organizations

Blood pressure medications given right after stroke not beneficial

Date:
February 19, 2014
Source:
Loyola University Health System
Summary:
Giving stroke patients medications to lower their blood pressure right after a stroke does not reduce death or major disability, a study has found. At least 25 percent of the population has high blood pressure, which greatly increases the risk of stroke. Lowering blood pressure has been shown to reduce the risk of stroke. The study investigated whether there also would be a benefit to lowering blood pressure immediately after a stroke. The study included more than 4,000 stroke patients in 26 hospitals, randomly assigned to receive or discontinue blood pressure medications. At 14 days or upon hospital discharge, there were no statistically significant differences between the groups in mortality or disability.

A major study has found that giving stroke patients medications to lower their blood pressure during the first 48 hours after a stroke does not reduce the likelihood of death or major disability. The study is published in the Journal of the American Medical Association.

At least 25 percent of the population has high blood pressure, which greatly increases the risk of stroke. Lowering blood pressure has been shown to reduce the risk of stroke. The study investigated whether there also would be a benefit to lowering blood pressure immediately after a stroke.

The study included more than 4,000 stroke patients in 26 hospitals across China, who were randomly assigned to receive blood pressure medications or to discontinue blood pressure medications. At 14 days or hospital discharge, there were no statistically significant differences between the groups in mortality or disability.

Blood pressure often is elevated following a stroke. “But in most cases, treatment is unnecessary because the blood pressure declines naturally over time, and lowering blood pressure may be contraindicated,” said stroke specialist Jose Biller, MD, chair of the Department of Neurology of Loyola University Medical Center. “It is important not to overtreat and cause low blood pressure, because the most important objective is to maintain adequate blood flow to the brain.”


Story Source:

The above story is based on materials provided by Loyola University Health System. Note: Materials may be edited for content and length.


Journal Reference:

  1. Jiang He, Yonghong Zhang, Tan Xu, Qi Zhao, Dali Wang, Chung-Shiuan Chen, Weijun Tong, Changjie Liu, Tian Xu, Zhong Ju, Yanbo Peng, Hao Peng, Qunwei Li, Deqin Geng, Jintao Zhang, Dong Li, Fengshan Zhang, Libing Guo, Yingxian Sun, Xuemei Wang, Yong Cui, Yongqiu Li, Dihui Ma, Guang Yang, Yanjun Gao, Xiaodong Yuan, Lydia A. Bazzano, Jing Chen. Effects of Immediate Blood Pressure Reduction on Death and Major Disability in Patients With Acute Ischemic Stroke. JAMA, 2014; 311 (5): 479 DOI: 10.1001/jama.2013.282543

Cite This Page:

Loyola University Health System. "Blood pressure medications given right after stroke not beneficial." ScienceDaily. ScienceDaily, 19 February 2014. <www.sciencedaily.com/releases/2014/02/140219142404.htm>.
Loyola University Health System. (2014, February 19). Blood pressure medications given right after stroke not beneficial. ScienceDaily. Retrieved August 22, 2014 from www.sciencedaily.com/releases/2014/02/140219142404.htm
Loyola University Health System. "Blood pressure medications given right after stroke not beneficial." ScienceDaily. www.sciencedaily.com/releases/2014/02/140219142404.htm (accessed August 22, 2014).

Share This




More Health & Medicine News

Friday, August 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Newsy (Aug. 21, 2014) An experimental drug used to treat Marburg virus in rhesus monkeys could give new insight into a similar treatment for Ebola. Video provided by Newsy
Powered by NewsLook.com
Two US Ebola Patients Leave Hospital Free of the Disease

Two US Ebola Patients Leave Hospital Free of the Disease

AFP (Aug. 21, 2014) Two American missionaries who were sickened with Ebola while working in Liberia and were treated with an experimental drug are doing better and have left the hospital, doctors say on August 21, 2014. Duration: 01:05 Video provided by AFP
Powered by NewsLook.com
Cadavers, a Teen, and a Medical School Dream

Cadavers, a Teen, and a Medical School Dream

AP (Aug. 21, 2014) Contains graphic content. He's only 17. But Johntrell Bowles has wanted to be a doctor from a young age, despite the odds against him. He was recently the youngest participant in a cadaver program at the Indiana University NW medical school. (Aug. 21) Video provided by AP
Powered by NewsLook.com
American Ebola Patients Released: What Cured Them?

American Ebola Patients Released: What Cured Them?

Newsy (Aug. 21, 2014) It's unclear whether the American Ebola patients' recoveries can be attributed to an experimental drug or early detection and good medical care. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins